Page last updated: 2024-10-31

muscimol and Central Nervous System Disease

muscimol has been researched along with Central Nervous System Disease in 3 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frølund, B1
Ebert, B1
Kristiansen, U1
Liljefors, T1
Krogsgaard-Larsen, P1
Ohkuma, S1
Chen, SH1
Katsura, M1
Chen, DZ1
Kuriyama, K1
Hikida, M1
Masukawa, Y1
Nishiki, K1
Inomata, N1

Reviews

1 review available for muscimol and Central Nervous System Disease

ArticleYear
GABA(A) receptor ligands and their therapeutic potentials.
    Current topics in medicinal chemistry, 2002, Volume: 2, Issue:8

    Topics: Animals; Central Nervous System Diseases; GABA Agents; GABA Agonists; GABA Antagonists; Humans; Ison

2002

Other Studies

2 other studies available for muscimol and Central Nervous System Disease

ArticleYear
Muscimol prevents neuronal injury induced by NMDA.
    Japanese journal of pharmacology, 1994, Volume: 64, Issue:2

    Topics: Animals; Cells, Cultured; Central Nervous System Diseases; Cerebral Cortex; L-Lactate Dehydrogenase;

1994
Low neurotoxicity of LJC 10,627, a novel 1 beta-methyl carbapenem antibiotic: inhibition of gamma-aminobutyric acidA, benzodiazepine, and glycine receptor binding in relation to lack of central nervous system toxicity in rats.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2

    Topics: Animals; Behavior, Animal; Binding, Competitive; Central Nervous System Diseases; Diazepam; GABA-A R

1993