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muscimol and Cataleptic Attacks

muscimol has been researched along with Cataleptic Attacks in 2 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Research Excerpts

ExcerptRelevanceReference
"Carbachol (10(-3) M)-induced cataplexy in narcoleptic canines was blocked by equimolar perfusion with the muscarinic antagonists atropine, gallamine, and 4-DAMP but not pirenzepine."1.30Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines. ( Dement, WC; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M, 1998)
"Both rapid eye movement sleep and cataplexy in the narcoleptic canine have been shown to increase after both systemic and local administration of cholinergic agonists in the pontine reticular formation."1.29Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors. ( Dement, WC; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reid, MS2
Tafti, M2
Nishino, S2
Siegel, JM2
Dement, WC2
Mignot, E2

Other Studies

2 other studies available for muscimol and Cataleptic Attacks

ArticleYear
Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors.
    Sleep, 1994, Volume: 17, Issue:5

    Topics: Animals; Cataplexy; Dogs; Electroencephalography; Female; Male; Microdialysis; Muscimol; Narcolepsy;

1994
Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines.
    Experimental neurology, 1998, Volume: 151, Issue:1

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropi

1998