muscimol has been researched along with Cardiac Failure in 5 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Muscimol was also less effective in decreasing RSND, BP, and HR in HF rats than in control rats." | 1.31 | Reduced endogenous GABA-mediated inhibition in the PVN on renal nerve discharge in rats with heart failure. ( Li, YF; Patel, KP; Zhang, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, RJ | 1 |
| Zeng, QH | 1 |
| Wang, WZ | 1 |
| Wang, W | 1 |
| Ramchandra, R | 1 |
| Hood, SG | 1 |
| Frithiof, R | 1 |
| McKinley, MJ | 1 |
| May, CN | 1 |
| Carillo, BA | 1 |
| Oliveira-Sales, EB | 1 |
| Andersen, M | 1 |
| Tufik, S | 1 |
| Hipolide, D | 1 |
| Santos, AA | 1 |
| Tucci, PJ | 1 |
| Bergamaschi, CT | 1 |
| Campos, RR | 1 |
| Potapenko, ES | 1 |
| Biancardi, VC | 1 |
| Zhou, Y | 1 |
| Stern, JE | 1 |
| Zhang, K | 1 |
| Li, YF | 1 |
| Patel, KP | 1 |
5 other studies available for muscimol and Cardiac Failure
| Article | Year |
|---|---|
GABA(A) and GABA(B) receptor-mediated inhibition of sympathetic outflow in the paraventricular nucleus is blunted in chronic heart failure.
Topics: Adrenergic Fibers; Animals; Baclofen; Bicuculline; Blood Pressure; Chronic Disease; GABA Agonists; G | 2009 |
The role of the paraventricular nucleus of the hypothalamus in the regulation of cardiac and renal sympathetic nerve activity in conscious normal and heart failure sheep.
Topics: Animals; Bicuculline; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glycine; Glycin | 2013 |
Changes in GABAergic inputs in the paraventricular nucleus maintain sympathetic vasomotor tone in chronic heart failure.
Topics: Animals; Autoradiography; Blood Pressure; Disease Models, Animal; Dizocilpine Maleate; Echocardiogra | 2012 |
Astrocytes modulate a postsynaptic NMDA-GABAA-receptor crosstalk in hypothalamic neurosecretory neurons.
Topics: Animals; Astrocytes; Calcium Signaling; Electrophysiological Phenomena; Excitatory Amino Acid Transp | 2013 |
Reduced endogenous GABA-mediated inhibition in the PVN on renal nerve discharge in rats with heart failure.
Topics: Animals; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hear | 2002 |