muscimol has been researched along with Brain Vascular Disorders in 3 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "If muscimol was combined with MK-801 at lower doses of each drug, the combination was neuroprotective (potency ratio of 4." | 1.29 | Combination chemotherapy extends the therapeutic window to 60 minutes after stroke. ( Lonzo, L; Lyden, P; Nunez, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lyden, P | 1 |
| Lonzo, L | 1 |
| Nunez, S | 1 |
| Schallert, T | 1 |
| Jones, TA | 1 |
| Lindner, MD | 1 |
| Hashimoto, T | 1 |
| Kimori, M | 1 |
| Nakamura, Y | 1 |
| Kuriyama, K | 1 |
1 review available for muscimol and Brain Vascular Disorders
| Article | Year |
|---|---|
Multilevel transneuronal degeneration after brain damage. Behavioral events and effects of anticonvulsant gamma-aminobutyric acid-related drugs.
Topics: Animals; Atrophy; Behavior, Animal; Cerebrovascular Disorders; Corpus Striatum; Diazepam; gamma-Amin | 1990 |
2 other studies available for muscimol and Brain Vascular Disorders
| Article | Year |
|---|---|
Combination chemotherapy extends the therapeutic window to 60 minutes after stroke.
Topics: Animals; Brain; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Therapy, Combination; Excitator | 1995 |
Effect of NC-1100 [1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride] on gamma-aminobutyric acid (GABA) metabolism in rat brain: analysis using stroke-prone spontaneously hypertensive rat.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Brain; Cerebrovascular Disorders; gamma-Aminobut | 1989 |