Page last updated: 2024-10-31

muscimol and Brain Disorders

muscimol has been researched along with Brain Disorders in 5 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Research Excerpts

ExcerptRelevanceReference
"This increased seizure susceptibility may be due to a functional immaturity of a substantia nigra, GABA-sensitive output system."2.37Epileptogenesis and the immature brain. ( Moshé, SL, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Ozdas, MS1
Shah, AS1
Johnson, PM1
Patel, N1
Marks, M1
Yasar, TB1
Stalder, U1
Bigler, L1
von der Behrens, W1
Sirsi, SR1
Yanik, MF1
Zimmerman, JM1
Rabinak, CA1
McLachlan, IG1
Maren, S1
Crossman, AR1
Sambrook, MA1
Jackson, A1
Moshé, SL1
Hikosaka, O1
Tanaka, M1
Sakamoto, M1
Iwamura, Y1

Reviews

1 review available for muscimol and Brain Disorders

ArticleYear
Epileptogenesis and the immature brain.
    Epilepsia, 1987, Volume: 28 Suppl 1

    Topics: Age Factors; Animals; Anticonvulsants; Brain; Brain Diseases; Cerebral Cortex; Epilepsy; Humans; Kin

1987

Other Studies

4 other studies available for muscimol and Brain Disorders

ArticleYear
Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers.
    Nature communications, 2020, 10-01, Volume: 11, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain Diseases; Dose-Response Relationship, Radiation; Drug Carriers;

2020
The central nucleus of the amygdala is essential for acquiring and expressing conditional fear after overtraining.
    Learning & memory (Cold Spring Harbor, N.Y.), 2007, Volume: 14, Issue:9

    Topics: Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Brain Diseases; Conditioning, Classical;

2007
Experimental hemichorea/hemiballismus in the monkey. Studies on the intracerebral site of action in a drug-induced dyskinesia.
    Brain : a journal of neurology, 1984, Volume: 107 ( Pt 2)

    Topics: Animals; Bicuculline; Brain Diseases; Brain Mapping; Chorea; Dyskinesia, Drug-Induced; Female; Globu

1984
Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey.
    Brain research, 1985, Jan-28, Volume: 325, Issue:1-2

    Topics: Animals; Brain Diseases; Brain Mapping; Female; gamma-Aminobutyric Acid; Hand; Macaca; Motor Skills;

1985