muscimol has been researched along with Bradyarrhythmia in 12 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin injections (5-HT, 2 microg/rat) in awake male Holtzman rats." | 3.73 | The bradycardic and hypotensive responses to serotonin are reduced by activation of GABAA receptors in the nucleus tractus solitarius of awake rats. ( Callera, JC; Colombari, E; De Luca, LA; Menani, JV, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, Y | 1 |
| Wu, YS | 1 |
| Chen, DS | 1 |
| Wang, MM | 1 |
| Wang, WZ | 1 |
| Yuan, WJ | 1 |
| Koba, S | 1 |
| Inoue, R | 1 |
| Watanabe, T | 1 |
| Burhans, LB | 1 |
| Schreurs, BG | 1 |
| Göktalay, G | 1 |
| Levendusky, MC | 1 |
| Millington, WR | 1 |
| Callera, JC | 3 |
| Colombari, E | 1 |
| De Luca, LA | 1 |
| Menani, JV | 1 |
| Williford, DJ | 1 |
| Hamilton, BL | 1 |
| Souza, JD | 1 |
| Williams, TP | 1 |
| DiMicco, JA | 1 |
| Gillis, RA | 1 |
| Hockman, CH | 1 |
| Weerasuriya, A | 1 |
| Bieger, D | 1 |
| Bonagamba, LG | 2 |
| Nosjean, A | 2 |
| Laguzzi, R | 2 |
| Machado, BH | 2 |
| Bousquet, P | 1 |
| Feldman, J | 1 |
| Bloch, R | 1 |
| Schwartz, J | 1 |
| Nosaka, S | 1 |
| Nakase, N | 1 |
| Murata, K | 1 |
| Bauer, RM | 1 |
| Vela, MB | 1 |
| Simon, T | 1 |
| Waldrop, TG | 1 |
12 other studies available for muscimol and Bradyarrhythmia
| Article | Year |
|---|---|
Microinjection of salusin-beta into the nucleus tractus solitarii inhibits cardiovascular function by suppressing presympathetic neurons in rostral ventrolateral medulla in rats.
Topics: Animals; Baroreflex; Bradycardia; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonist | 2015 |
Role played by periaqueductal gray neurons in parasympathetically mediated fear bradycardia in conscious rats.
Topics: Animals; Bradycardia; Consciousness; Fear; Freezing Reaction, Cataleptic; GABA-A Receptor Agonists; | 2016 |
Inactivation of the central nucleus of the amygdala blocks classical conditioning but not conditioning-specific reflex modification of rabbit heart rate.
Topics: Amygdala; Animals; Autonomic Nervous System; Bradycardia; Conditioning, Classical; Heart Rate; Male; | 2013 |
Muscimol injection into the lateral hypothalamus inhibits the hypotension and bradycardia caused by somato-visceral nociception.
Topics: Animals; Bradycardia; Cardiovascular Physiological Phenomena; GABA Agonists; Homocysteine; Hypotensi | 2004 |
The bradycardic and hypotensive responses to serotonin are reduced by activation of GABAA receptors in the nucleus tractus solitarius of awake rats.
Topics: Animals; Baclofen; Blood Pressure; Bradycardia; GABA Agonists; Heart Rate; Hypotension; Male; Muscim | 2005 |
Central nervous system mechanisms involving GABA influence arterial pressure and heart rate in the cat.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Bradycardia; Cats; Central Nervous System; Clonid | 1980 |
GABA receptor-mediated inhibition of reflex deglutition in the cat.
Topics: Animals; Bradycardia; Cats; Deglutition; Deglutition Disorders; Diazepam; Female; GABA Antagonists; | 1996 |
Activation of GABAA but not GABAB receptors in the NTSblocked bradycardia of chemoreflex in awake rats.
Topics: Animals; Baclofen; Bradycardia; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; GABA Ag | 1999 |
Activation of GABA receptors in the NTS of awake rats reduces the gain of baroreflex bradycardia.
Topics: Animals; Antihypertensive Agents; Baclofen; Baroreflex; Blood Pressure; Bradycardia; Cardiotonic Age | 2000 |
[Ventrobulbular hypotensive action of muscimol].
Topics: Animals; Bradycardia; Brain Stem; Cats; Female; Hypotension; Male; Muscimol; Oxazoles | 1978 |
Somatosensory and hypothalamic inhibitions of baroreflex vagal bradycardia in rats.
Topics: Animals; Bicuculline; Bradycardia; Electric Stimulation; Hypothalamus; Male; Muscimol; Neural Inhibi | 1989 |
A GABAergic mechanism in the posterior hypothalamus modulates baroreflex bradycardia.
Topics: Animals; Bradycardia; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamu | 1988 |