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muscimol and Body Weight

muscimol has been researched along with Body Weight in 17 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice."7.74Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008)
" In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice."3.74Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008)
"The sensitivity of prenatal protein malnourished rats to the amnestic properties of the direct GABAA receptor agonist muscimol and the selective benzodiazepine (BZ) receptor agonist, CL218,872, was studied in the male offspring of rats provided with a protein deficient diet (6% casein) for 5 weeks prior to mating and throughout pregnancy."3.72Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition. ( Bonnie, KE; Duran, P; Galler, JR; Hudson, JL; Shultz, PL; Tonkiss, J, 2003)
"Long-term, periodic, transmeningeal muscimol delivery with the SPD is essentially a safe procedure."1.38Long-term behavioral, electrophysiological, and neurochemical monitoring of the safety of an experimental antiepileptic implant, the muscimol-delivering Subdural Pharmacotherapy Device in monkeys. ( Baptiste, SL; Carlson, C; Devinsky, O; French, JA; Kuzniecky, RI; Ludvig, N; Medveczky, G; Stefanov, DG; Tang, HM; Vaynberg, JK; Vazquez-DeRose, J, 2012)
"Treatment with melatonin (5 mg/kg and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared with control (sleep-deprived)."1.35Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. ( Kumar, A; Singh, A, 2009)
"Sleep-wake states were studied following withdrawal in 36 adult male wistar alcohol-dependent rats, after chronic administration of ethanol (10 g/kg/24 h) for 13 days."1.30Effects of muscimol or homotaurine on sleep-wake states in alcohol-dependent rats during withdrawal. ( Bajenaru, O; Dall'Ava-Santucci, J; Dinh-Xuan, AT; Emmanouilidis, E; Manicom, R; Poenaru, S; Rouhani, S; Tran, G, 1998)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's5 (29.41)18.2507
2000's8 (47.06)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hao, S1
Yang, H1
Wang, X1
He, Y1
Xu, H2
Wu, X1
Pan, L1
Liu, Y1
Lou, H1
Ma, H1
Xi, W1
Zhou, Y1
Duan, S1
Wang, H1
Singh, A2
Kumar, A2
Turenius, CI1
Htut, MM1
Prodon, DA1
Ebersole, PL1
Ngo, PT1
Lara, RN1
Wilczynski, JL1
Stanley, BG1
Chen, F1
Cham, JL1
Badoer, E1
Ludvig, N1
Tang, HM1
Baptiste, SL1
Medveczky, G1
Vaynberg, JK1
Vazquez-DeRose, J1
Stefanov, DG1
Devinsky, O1
French, JA1
Carlson, C1
Kuzniecky, RI1
Nuñez, JL1
Alt, JJ1
McCarthy, MM1
Tonkiss, J1
Shultz, PL1
Bonnie, KE1
Hudson, JL1
Duran, P1
Galler, JR1
Simjee, SU1
Pleuvry, BJ1
Coulthard, P1
Coppola, JD1
Horwitz, BA1
Hamilton, J1
Blevins, JE1
McDonald, RB1
Cooper, BR1
Howard, JL1
White, HL1
Soroko, F1
Ingold, K1
Maxwell, RA1
Overton, JM1
Redding, MW1
Yancey, SL1
Stremel, RW1
Rouhani, S2
Dall'Ava-Santucci, J1
Bajenaru, O1
Emmanouilidis, E2
Tran, G2
Manicom, R1
Dinh-Xuan, AT1
Poenaru, S2
Blaine, K1
Gasser, K1
Conway, S1
Bailey, CD1
Brien, JF1
Reynolds, JN1
Yang, RH1
Jin, HK1
Wyss, JM1
Chen, YF1
Oparil, S1
Payan, C1
Castresana, A1
Soulairac, A1

Other Studies

17 other studies available for muscimol and Body Weight

ArticleYear
The Lateral Hypothalamic and BNST GABAergic Projections to the Anterior Ventrolateral Periaqueductal Gray Regulate Feeding.
    Cell reports, 2019, 07-16, Volume: 28, Issue:3

    Topics: Animals; Antipsychotic Agents; Body Weight; Central Amygdaloid Nucleus; Clozapine; Feeding Behavior;

2019
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:9

    Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumaze

2008
GABA(A) receptors in the lateral hypothalamus as mediators of satiety and body weight regulation.
    Brain research, 2009, Mar-25, Volume: 1262

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Feeding Behavior; GABA Agonists; GABA Antago

2009
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
    Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:4

    Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Fem

2009
High-fat feeding alters the cardiovascular role of the hypothalamic paraventricular nucleus.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:3

    Topics: Adipose Tissue; Animals; Bicuculline; Blood Glucose; Blood Pressure; Body Weight; Cardiovascular Sys

2010
Long-term behavioral, electrophysiological, and neurochemical monitoring of the safety of an experimental antiepileptic implant, the muscimol-delivering Subdural Pharmacotherapy Device in monkeys.
    Journal of neurosurgery, 2012, Volume: 117, Issue:1

    Topics: Animals; Anticonvulsants; Behavior, Animal; Body Weight; Cerebrospinal Fluid Proteins; Chromatograph

2012
A novel model for prenatal brain damage. II. Long-term deficits in hippocampal cell number and hippocampal-dependent behavior following neonatal GABAA receptor activation.
    Experimental neurology, 2003, Volume: 181, Issue:2

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain Damage, Chronic; Cell Count; Chronic

2003
Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition.
    Nutritional neuroscience, 2003, Volume: 6, Issue:6

    Topics: Animals; Body Weight; Female; GABA Agonists; GABA-A Receptor Agonists; Learning Disabilities; Motor

2003
Modulation of the gait deficit in arthritic rats by infusions of muscimol and bicuculline.
    Pain, 2004, Volume: 109, Issue:3

    Topics: Animals; Arthralgia; Arthritis, Experimental; Body Weight; Disease Models, Animal; Dose-Response Rel

2004
Reduced feeding response to muscimol and neuropeptide Y in senescent F344 rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:6

    Topics: Adrenergic alpha-Agonists; Aging; Animals; Appetite Stimulants; Body Weight; Drug Interactions; Eati

2005
Anorexic effects of ethanolamine-O-sulfate and muscimol in the rat: evidence that GABA inhibits ingestive behavior.
    Life sciences, 1980, Jun-09, Volume: 26, Issue:23

    Topics: 4-Aminobutyrate Transaminase; Animals; Appetite Depressants; Body Weight; Brain Chemistry; Dextroamp

1980
Hypothalamic GABAergic influences on treadmill exercise responses in rats.
    Brain research bulletin, 1994, Volume: 33, Issue:5

    Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; GABA Antagonists; gamma-Aminobutyric Acid; H

1994
Effects of muscimol or homotaurine on sleep-wake states in alcohol-dependent rats during withdrawal.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:4

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Body Weight; Central Nervous System D

1998
Influence of fetal alcohol exposure on the GABAergic regulation of growth hormone release in postnatal rats.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:10

    Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Body Weight; Central Nervous System Depressants

1999
Chronic prenatal ethanol exposure increases GABA(A) receptor subunit protein expression in the adult guinea pig cerebral cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jun-15, Volume: 21, Issue:12

    Topics: Administration, Oral; Animals; Body Weight; Cerebral Cortex; Dizocilpine Maleate; Drug Administratio

2001
Pressor effect of blocking atrial natriuretic peptide in nucleus tractus solitarii.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Heart Rate;

1992
Effects of alcohol dependence on shock-induced fighting: action of muscimol and homotaurine.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Aggression; Alcoholism; Animals; Body Weight; Electroshock; Ethanol; gamma-Aminobutyric Acid; Male;

1992