muscimol has been researched along with Benign Psychomotor Epilepsy, Childhood in 10 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizure-induced release of the neuromodulator adenosine is a potent endogenous anticonvulsant mechanism, which limits the extension of seizures and mediates seizure arrest." | 7.78 | Adenosine release during seizures attenuates GABAA receptor-mediated depolarization. ( Akerman, CJ; Ilie, A; Raimondo, JV, 2012) |
| "Seizure-induced release of the neuromodulator adenosine is a potent endogenous anticonvulsant mechanism, which limits the extension of seizures and mediates seizure arrest." | 3.78 | Adenosine release during seizures attenuates GABAA receptor-mediated depolarization. ( Akerman, CJ; Ilie, A; Raimondo, JV, 2012) |
| " Two animal models of TLE--amygdala kindling and pilocarpine-induced status epilepticus (Pilo-SE)--were tested." | 3.75 | Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics. ( Leung, LS; Long, JJ; Luo, T; McMurran, TJ; Shen, B; Stewart, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, X | 1 |
| Yao, Y | 1 |
| Li, X | 1 |
| Dong, J | 1 |
| Zhang, A | 1 |
| Long, JJ | 1 |
| Shen, B | 1 |
| Luo, T | 1 |
| Stewart, L | 1 |
| McMurran, TJ | 1 |
| Leung, LS | 2 |
| Langlois, M | 1 |
| Polack, PO | 1 |
| Bernard, H | 1 |
| David, O | 1 |
| Charpier, S | 1 |
| Depaulis, A | 1 |
| Deransart, C | 1 |
| Sloan, DM | 1 |
| Zhang, D | 1 |
| Bertram, EH | 2 |
| Ilie, A | 1 |
| Raimondo, JV | 1 |
| Akerman, CJ | 1 |
| Stewart, LS | 1 |
| Vorobyov, V | 1 |
| Schibaev, N | 1 |
| Kovalev, G | 1 |
| Alzheimer, C | 1 |
| Ma, J | 1 |
| Brudzynski, SM | 1 |
| Leung, LW | 1 |
| Zhang, X | 1 |
| Le Gal La Salle, G | 1 |
| Ridoux, V | 1 |
| Yu, PH | 1 |
| Ju, G | 1 |
| Lothman, EW | 1 |
| Kapur, J | 1 |
| Stringer, JL | 1 |
10 other studies available for muscimol and Benign Psychomotor Epilepsy, Childhood
| Article | Year |
|---|---|
Alteration of GABAergic signaling is associated with anxiety-like behavior in temporal lobe epilepsy mice.
Topics: Animals; Anxiety; Blotting, Western; Disease Models, Animal; Epilepsy, Temporal Lobe; GABAergic Neur | 2019 |
Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics.
Topics: Anesthetics, General; Animals; Brain; Consciousness Disorders; Convulsants; Disease Models, Animal; | 2009 |
Involvement of the thalamic parafascicular nucleus in mesial temporal lobe epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biophysical Phenomena; Disease Models, Anim | 2010 |
Increased GABAergic inhibition in the midline thalamus affects signaling and seizure spread in the hippocampus-prefrontal cortex pathway.
Topics: Animals; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; G | 2011 |
Adenosine release during seizures attenuates GABAA receptor-mediated depolarization.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; CA3 Region, Hippocampal; Chlorides; Epilepsy, Te | 2012 |
Hippocampal melatonin receptors modulate seizure threshold.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy | 2005 |
Effects of neurotransmitter agonists on electrocortical activity in the rat kainate model of temporal lobe epilepsy and the modulatory action of basic fibroblast growth factor.
Topics: Animals; Baclofen; Clonidine; Electroencephalography; Epilepsy, Temporal Lobe; Fibroblast Growth Fac | 2005 |
Involvement of the nucleus accumbens-ventral pallidal pathway in postictal behavior induced by a hippocampal afterdischarge in rats.
Topics: Animals; Behavior, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electric Stimulat | 1996 |
Prevention of kainic acid-induced limbic seizures and Fos expression by the GABA-A receptor agonist muscimol.
Topics: Animals; Behavior, Animal; Brain Chemistry; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; | 1997 |
Recurrent spontaneous hippocampal seizures in the rat as a chronic sequela to limbic status epilepticus.
Topics: Action Potentials; Animals; Chronic Disease; Disease Models, Animal; Electric Stimulation; Electroen | 1990 |