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muscimol and Basal Ganglia Diseases

muscimol has been researched along with Basal Ganglia Diseases in 5 studies

Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.

Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"The tremor was accompanied by coherent oscillations in the local field potential (LFP)."1.48Loss of Balance between Striatal Feedforward Inhibition and Corticostriatal Excitation Leads to Tremor. ( Bar-Gad, I; Oran, Y, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oran, Y1
Bar-Gad, I1
Takakusaki, K1
Habaguchi, T1
Ohtinata-Sugimoto, J1
Saitoh, K1
Sakamoto, T1
Johnson, AE1
Liminga, U1
Lidén, A1
Lindefors, N1
Gunne, LM1
Wiesel, FA1
Oakley, NR1
Hayes, AG1
Sheehan, MJ1
Schwarz, M1
Löscher, W1
Turski, L1
Sontag, KH1

Other Studies

5 other studies available for muscimol and Basal Ganglia Diseases

ArticleYear
Loss of Balance between Striatal Feedforward Inhibition and Corticostriatal Excitation Leads to Tremor.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018, 02-14, Volume: 38, Issue:7

    Topics: Adamantane; Animals; Basal Ganglia Diseases; Cerebral Cortex; Corpus Striatum; Evoked Potentials; Fe

2018
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
    Neuroscience, 2003, Volume: 119, Issue:1

    Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-A

2003
Chronic treatment with a classical neuroleptic alters excitatory amino acid and GABAergic neurotransmission in specific regions of the rat brain.
    Neuroscience, 1994, Volume: 63, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Autoradiogr

1994
Effect of typical and atypical neuroleptics on the behavioural consequences of activation by muscimol of mesolimbic and nigro-striatal dopaminergic pathways in the rat.
    Psychopharmacology, 1991, Volume: 105, Issue:2

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Brain Chemistry; Corpus Str

1991
Disturbed GABAergic transmission in mutant Han-Wistar rats: further evidence for basal ganglia dysfunction.
    Brain research, 1985, Nov-18, Volume: 347, Issue:2

    Topics: Animals; Basal Ganglia Diseases; Bicuculline; Brain Chemistry; Electromyography; Female; gamma-Amino

1985