muscimol has been researched along with Autism Spectrum Disorder in 2 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prenatal exposure to valproic acid (VPA) enhances the risk for later development of autism spectrum disorders (ASD)." | 3.85 | Increased GABAA receptor binding in amygdala after prenatal administration of valproic acid to rats. ( Bertelsen, F; Drasbek, KR; Folloni, D; Landau, AM; Møller, A; Scheel-Krüger, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vacher, CM | 1 |
| Lacaille, H | 1 |
| O'Reilly, JJ | 1 |
| Salzbank, J | 1 |
| Bakalar, D | 1 |
| Sebaoui, S | 1 |
| Liere, P | 1 |
| Clarkson-Paredes, C | 1 |
| Sasaki, T | 1 |
| Sathyanesan, A | 1 |
| Kratimenos, P | 1 |
| Ellegood, J | 1 |
| Lerch, JP | 1 |
| Imamura, Y | 1 |
| Popratiloff, A | 1 |
| Hashimoto-Torii, K | 1 |
| Gallo, V | 1 |
| Schumacher, M | 1 |
| Penn, AA | 1 |
| Bertelsen, F | 1 |
| Møller, A | 1 |
| Folloni, D | 1 |
| Drasbek, KR | 1 |
| Scheel-Krüger, J | 1 |
| Landau, AM | 1 |
2 other studies available for muscimol and Autism Spectrum Disorder
| Article | Year |
|---|---|
Placental endocrine function shapes cerebellar development and social behavior.
Topics: Aldehyde Reductase; Animals; Autism Spectrum Disorder; Cerebellum; Endocrine Glands; Female; GABA Ag | 2021 |
Increased GABAA receptor binding in amygdala after prenatal administration of valproic acid to rats.
Topics: Amygdala; Animals; Autism Spectrum Disorder; Autoradiography; Azides; Benzodiazepines; Carbon Radioi | 2017 |