muscimol has been researched along with Anxiety in 63 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 7.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| "In the present study, we have investigated the effects and the interaction of the GABAergic and histaminergic systems in the basolateral amygdala (BLA) of rats using the plus-maze test of anxiety-like behaviors." | 7.74 | GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors. ( Hajizadeh Moghaddam, A; Heidary-Davishani, A; Roohbakhsh, A; Rostami, P; Zarrindast, MR, 2008) |
| " On the contrary, caffeine produced higher anxiety in animals previously treated with the GABA(A) receptor antagonist, bicuculline or either of the various neurosteroid biosynthesis enzyme inhibitors viz." | 7.73 | Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats. ( Chopde, CT; Hirani, K; Jain, NS, 2005) |
| "The contribution of GABAergic mechanisms to rat emotional behavior in two animal models of anxiety (open field test of neophobia and aversively conditioned freezing reaction), was confirmed by pharmacological analysis, using anxiolytic (midazolam) and anxiogenic (picrotoxin) compounds." | 7.72 | Rat behavior in two models of anxiety and brain [3H]muscimol binding: pharmacological, correlation, and multifactor analysis. ( Bidziński, A; Członkowska, AI; Lehner, M; Maciejak, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J; Turzyńska, D; Wisłowska, A; Zienowicz, M, 2003) |
| "Differential effects of brain region inactivation on anxiety-like behaviour were shown by measures in the EPM and ET; muscimol infused into the PrL-reduced anxiety-like behaviour, yet had no significant effect when infused into the OFC, compared with control treated rats." | 3.96 | Differential effects of GABA ( Baracz, SJ; Cornish, JL; Everett, NA; Green, TA; Robinson, KJ, 2020) |
| "In an attempt to establish a relationship between food intake and fear/anxiety-related behaviours, the goal of this study was to investigate the effect of bilateral injections of GABAA (Muscimol, MUS, doses 25 and 50ng/side) and GABAB (Baclofen, BAC, doses 32 and 64ng/side) receptor agonists in the nucleus accumbens shell (AcbSh) on the level of fear/anxiety-like and feeding behaviours in 24h food-deprived rats." | 3.78 | Effects of GABA ligands injected into the nucleus accumbens shell on fear/anxiety-like and feeding behaviours in food-deprived rats. ( Borges, AC; Faria, MS; Ganzer, L; Januário, AC; Kochenborger, L; Lopes, AP; Marino-Neto, J; Paschoalini, MA, 2012) |
| " We here examined autoradiographic binding of [(3)H]muscimol to measure the total population of GABA(A) receptors and [(3)H]flunitrazepam to assess density of benzodiazepine sites in the medial prefrontal cortex, bed nucleus of the stria terminalis, amygdala, hippocampus, and periaqueductal gray of female rats sacrificed on day 7 postpartum, day 10 of pregnancy, or as diestrous virgins." | 3.77 | Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats. ( Lonstein, JS; Miller, SM, 2011) |
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 3.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| "This study investigated the effect of GABAA (muscimol, MUSC) and GABAB (baclofen, BACL) agonist receptors microinjected into medial accumbens shell on feeding and the level of fear in free-feeding rats submitted to the elevated plus-maze (EPM), an animal model of anxiety." | 3.74 | GABAA and GABAB agonist microinjections into medial accumbens shell increase feeding and induce anxiolysis in an animal model of anxiety. ( da Cunha, IC; de Lima, TC; Faria, MS; Ferraz, A; Lopes, AP; Neto, JM; Paschoalini, MA; Steffens, SM; Vargas, JC, 2007) |
| "In the present study, we have investigated the effects and the interaction of the GABAergic and histaminergic systems in the basolateral amygdala (BLA) of rats using the plus-maze test of anxiety-like behaviors." | 3.74 | GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors. ( Hajizadeh Moghaddam, A; Heidary-Davishani, A; Roohbakhsh, A; Rostami, P; Zarrindast, MR, 2008) |
| " On the contrary, caffeine produced higher anxiety in animals previously treated with the GABA(A) receptor antagonist, bicuculline or either of the various neurosteroid biosynthesis enzyme inhibitors viz." | 3.73 | Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats. ( Chopde, CT; Hirani, K; Jain, NS, 2005) |
| "The contribution of GABAergic mechanisms to rat emotional behavior in two animal models of anxiety (open field test of neophobia and aversively conditioned freezing reaction), was confirmed by pharmacological analysis, using anxiolytic (midazolam) and anxiogenic (picrotoxin) compounds." | 3.72 | Rat behavior in two models of anxiety and brain [3H]muscimol binding: pharmacological, correlation, and multifactor analysis. ( Bidziński, A; Członkowska, AI; Lehner, M; Maciejak, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J; Turzyńska, D; Wisłowska, A; Zienowicz, M, 2003) |
| "Thus, mechanical hyperalgesia and allodynia, and the pattern of c-Fos staining in the amygdala subnuclei were evaluated in rats with chronic constriction of the sciatic nerve, as well as sham-operated and naïve rats." | 1.48 | The critical role of amygdala subnuclei in nociceptive and depressive-like behaviors in peripheral neuropathy. ( Antunes, GF; Assis, DV; Gouveia, F; Kuroki, M; Martinez, RCR; Oliveira, CC; Pagano, RL; Santos, LCT; Seno, MDJ, 2018) |
| "Muscimol pretreatment did not change D-AP5-induced anxiolytic-like behaviors but potentiated avoidance memory impairment." | 1.43 | The role of CA3 GABAA receptors on anxiolytic-like behaviors and avoidance memory deficit induced by NMDA receptor antagonists. ( Farahizadeh, M; Nasehi, M; Zarrabian, S; Zarrindast, MR, 2016) |
| "However, RVM inactivation blocked the hyperalgesia produced upon removal from the EPM." | 1.38 | Contribution of the rostral ventromedial medulla to post-anxiety induced hyperalgesia. ( Cornélio, AM; Morgan, MM; Nunes-de-Souza, RL, 2012) |
| "Treatment with melatonin (5 and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared to control (sleep deprived)." | 1.37 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice. ( Kumar, A; Kumar, P; Singh, A, 2011) |
| "Muscimol was effective in reducing AEP in both LA and HA rats." | 1.36 | GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure. ( Brandão, ML; Cabral, A; Nobre, MJ, 2010) |
| "Treatment with melatonin (5 mg/kg and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared with control (sleep-deprived)." | 1.35 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. ( Kumar, A; Singh, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (9.52) | 18.7374 |
| 1990's | 6 (9.52) | 18.2507 |
| 2000's | 20 (31.75) | 29.6817 |
| 2010's | 28 (44.44) | 24.3611 |
| 2020's | 3 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Shao, FB | 1 |
| Fang, JF | 1 |
| Wang, SS | 1 |
| Qiu, MT | 1 |
| Xi, DN | 1 |
| Jin, XM | 1 |
| Liu, JG | 1 |
| Shao, XM | 1 |
| Shen, Z | 1 |
| Liang, Y | 1 |
| Fang, JQ | 1 |
| Du, JY | 1 |
| Green, TA | 1 |
| Baracz, SJ | 1 |
| Everett, NA | 1 |
| Robinson, KJ | 1 |
| Cornish, JL | 1 |
| Sabihi, S | 1 |
| Goodpaster, C | 1 |
| Maurer, S | 1 |
| Leuner, B | 1 |
| Sugiyama, A | 1 |
| Yamada, M | 2 |
| Saitoh, A | 2 |
| Nagase, H | 1 |
| Oka, JI | 1 |
| Seno, MDJ | 1 |
| Assis, DV | 1 |
| Gouveia, F | 1 |
| Antunes, GF | 1 |
| Kuroki, M | 1 |
| Oliveira, CC | 1 |
| Santos, LCT | 1 |
| Pagano, RL | 1 |
| Martinez, RCR | 1 |
| Zhu, X | 1 |
| Yao, Y | 1 |
| Li, X | 1 |
| Dong, J | 1 |
| Zhang, A | 1 |
| Glover, EJ | 1 |
| Starr, EM | 1 |
| Chao, Y | 1 |
| Jhou, TC | 1 |
| Chandler, LJ | 1 |
| Nobre, MJ | 2 |
| Salunke, BP | 1 |
| Umathe, SN | 1 |
| Chavan, JG | 1 |
| Lungwitz, EA | 1 |
| Stuber, GD | 1 |
| Johnson, PL | 1 |
| Dietrich, AD | 1 |
| Schartz, N | 1 |
| Hanrahan, B | 1 |
| Shekhar, A | 5 |
| Truitt, WA | 1 |
| Zhang, WN | 1 |
| Bast, T | 1 |
| Xu, Y | 1 |
| Feldon, J | 1 |
| Hamilton, TJ | 1 |
| Holcombe, A | 1 |
| Tresguerres, M | 1 |
| Naseri, MH | 1 |
| Hesami-Tackallou, S | 1 |
| Torabi-Nami, M | 1 |
| Zarrindast, MR | 4 |
| Nasehi, M | 2 |
| Jiang, H | 1 |
| Fang, D | 1 |
| Kong, LY | 1 |
| Jin, ZR | 1 |
| Cai, J | 1 |
| Kang, XJ | 1 |
| Wan, Y | 1 |
| Xing, GG | 1 |
| Sollozo-Dupont, I | 1 |
| Estrada-Camarena, E | 1 |
| Carro-Juárez, M | 1 |
| López-Rubalcava, C | 2 |
| Chee, SS | 1 |
| Menard, JL | 2 |
| Dringenberg, HC | 1 |
| Rysakova, MP | 1 |
| Pavlova, IV | 1 |
| Salari, AA | 1 |
| Bakhtiari, A | 1 |
| Homberg, JR | 1 |
| Zarrabian, S | 1 |
| Farahizadeh, M | 1 |
| Li, C | 1 |
| Yan, Y | 1 |
| Cheng, J | 1 |
| Xiao, G | 1 |
| Gu, J | 1 |
| Zhang, L | 1 |
| Yuan, S | 1 |
| Wang, J | 1 |
| Shen, Y | 1 |
| Zhou, YD | 1 |
| Hirose, N | 1 |
| Kamei, J | 1 |
| Lamontagne, SJ | 1 |
| Olmstead, MC | 1 |
| Forcelli, PA | 1 |
| DesJardin, JT | 1 |
| West, EA | 1 |
| Holmes, AL | 1 |
| Elorette, C | 1 |
| Wellman, LL | 1 |
| Malkova, L | 1 |
| Esclassan, F | 1 |
| Coutureau, E | 1 |
| Di Scala, G | 1 |
| Marchand, AR | 1 |
| Solati, J | 1 |
| Oryan, S | 2 |
| Parivar, K | 1 |
| Christianson, JP | 1 |
| Thompson, BM | 1 |
| Watkins, LR | 1 |
| Maier, SF | 1 |
| Kumar, A | 4 |
| Goyal, R | 1 |
| Prakash, A | 1 |
| Singh, A | 3 |
| Cabral, A | 1 |
| Brandão, ML | 1 |
| Kumar, P | 1 |
| Miller, SM | 1 |
| Lonstein, JS | 1 |
| Ashabi, G | 1 |
| Ahmadi, R | 1 |
| Valizadegan, F | 1 |
| Lopes, AP | 2 |
| Ganzer, L | 1 |
| Borges, AC | 1 |
| Kochenborger, L | 1 |
| Januário, AC | 1 |
| Faria, MS | 2 |
| Marino-Neto, J | 1 |
| Paschoalini, MA | 2 |
| Cornélio, AM | 1 |
| Nunes-de-Souza, RL | 1 |
| Morgan, MM | 1 |
| Sévoz-Couche, C | 1 |
| Brouillard, C | 1 |
| Camus, F | 1 |
| Laude, D | 1 |
| De Boer, SF | 1 |
| Becker, C | 1 |
| Benoliel, JJ | 1 |
| Kosari-Nasab, M | 1 |
| Babri, S | 1 |
| Fatehi-Gharehlar, L | 1 |
| Doosti, MH | 1 |
| Pakzad, S | 1 |
| Fendt, M | 1 |
| Endres, T | 1 |
| Apfelbach, R | 1 |
| Kralic, JE | 1 |
| Wheeler, M | 1 |
| Renzi, K | 1 |
| Ferguson, C | 1 |
| O'Buckley, TK | 1 |
| Grobin, AC | 1 |
| Morrow, AL | 1 |
| Homanics, GE | 1 |
| Sena, LM | 1 |
| Bueno, C | 1 |
| Pobbe, RL | 1 |
| Andrade, TG | 1 |
| Zangrossi, H | 2 |
| Viana, MB | 1 |
| Sienkiewicz-Jarosz, H | 1 |
| Szyndler, J | 1 |
| Członkowska, AI | 1 |
| Siemiatkowski, M | 1 |
| Maciejak, P | 1 |
| Wisłowska, A | 1 |
| Zienowicz, M | 1 |
| Lehner, M | 1 |
| Turzyńska, D | 1 |
| Bidziński, A | 1 |
| Płaźnik, A | 1 |
| Sinkkonen, ST | 1 |
| Lüscher, B | 1 |
| Lüddens, H | 1 |
| Korpi, ER | 2 |
| Shah, AA | 1 |
| Sjovold, T | 1 |
| Treit, D | 1 |
| Dos Santos, L | 1 |
| de Andrade, TG | 1 |
| Jain, NS | 1 |
| Hirani, K | 2 |
| Chopde, CT | 2 |
| Piña-Medina, B | 1 |
| Estrada-Reyes, R | 1 |
| Heinze, G | 1 |
| Martínez-Vázquez, M | 1 |
| da Cunha, IC | 1 |
| Steffens, SM | 1 |
| Ferraz, A | 1 |
| Vargas, JC | 1 |
| de Lima, TC | 1 |
| Neto, JM | 1 |
| Ugale, RR | 1 |
| Sharma, AN | 1 |
| Kokare, DM | 1 |
| Subhedar, NK | 1 |
| Hajizadeh Moghaddam, A | 1 |
| Roohbakhsh, A | 1 |
| Rostami, P | 1 |
| Heidary-Davishani, A | 1 |
| Katner, JS | 1 |
| Sims, LS | 1 |
| Bowsher, RR | 1 |
| Sanders, SK | 1 |
| Pokk, P | 1 |
| Liljequist, S | 1 |
| Zharkovsky, A | 1 |
| Yu, YH | 1 |
| Blessing, WW | 1 |
| Sasaki, K | 1 |
| Fan, LW | 1 |
| Tien, LT | 1 |
| Ma, T | 1 |
| Loh, HH | 1 |
| Ho, IK | 1 |
| Tuominen, K | 1 |
| Rägo, L | 2 |
| Kiivet, RA | 2 |
| Harro, J | 2 |
| Pŏld, M | 2 |
| Quintero, S | 1 |
| Henney, S | 1 |
| Lawson, P | 1 |
| Mellanby, J | 2 |
| Gray, JA | 2 |
| Lloyd, KG | 1 |
| Perrault, G | 1 |
| Zivkovic, B | 1 |
| Buckland, C | 1 |
| Drugan, RC | 1 |
| Skolnick, P | 1 |
| Paul, SM | 1 |
| Crawley, JN | 1 |
1 review available for muscimol and Anxiety
| Article | Year |
|---|---|
[Implications of GABAergic synapses in neuropsychiatry].
Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; | 1985 |
62 other studies available for muscimol and Anxiety
| Article | Year |
|---|---|
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Central Nervous System Sensitization; Chronic Pain; Clozapine | 2021 |
Differential effects of GABA
Topics: Animals; Anxiety; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol | 2020 |
GABA in the medial prefrontal cortex regulates anxiety-like behavior during the postpartum period.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Ago | 2021 |
Administration of a delta opioid receptor agonist KNT-127 to the basolateral amygdala has robust anxiolytic-like effects in rats.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Basolateral Nuclear Complex; Fea | 2018 |
The critical role of amygdala subnuclei in nociceptive and depressive-like behaviors in peripheral neuropathy.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Basolateral Nuclear Complex; Central Amygdaloid Nucle | 2018 |
Alteration of GABAergic signaling is associated with anxiety-like behavior in temporal lobe epilepsy mice.
Topics: Animals; Anxiety; Blotting, Western; Disease Models, Animal; Epilepsy, Temporal Lobe; GABAergic Neur | 2019 |
Inhibition of the rostromedial tegmental nucleus reverses alcohol withdrawal-induced anxiety-like behavior.
Topics: Action Potentials; Animals; Anxiety; Behavior, Animal; Ethanol; GABA-A Receptor Agonists; Male; Musc | 2019 |
Changes on auditory physiology in response to the inactivation of amygdala nuclei in high anxiety rats expressing learned fear.
Topics: Amygdala; Animals; Anxiety; Conditioning, Psychological; Evoked Potentials, Auditory; Fear; GABA Ago | 2013 |
Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice.
Topics: Animals; Anxiety; Bicuculline; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; gamma-A | 2014 |
The role of the medial prefrontal cortex in regulating social familiarity-induced anxiolysis.
Topics: Analysis of Variance; Animals; Antimetabolites; Anxiety; Cues; Cycloserine; Disease Models, Animal; | 2014 |
Temporary inhibition of dorsal or ventral hippocampus by muscimol: distinct effects on measures of innate anxiety on the elevated plus maze, but similar disruption of contextual fear conditioning.
Topics: Animals; Anxiety; Conditioning, Psychological; Fear; GABA-A Receptor Agonists; Hippocampus; Male; Mu | 2014 |
CO2-induced ocean acidification increases anxiety in rockfish via alteration of GABAA receptor functioning.
Topics: Animals; Anxiety; Behavior, Animal; Carbon Dioxide; Environmental Exposure; Fish Proteins; GABA Anta | 2014 |
Involvement of the CA1 GABAA receptors in MK-801-induced anxiolytic-like effects: an isobologram analysis.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; CA1 Region, Hippocampal; D | 2014 |
Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats.
Topics: Action Potentials; Animals; Anxiety; Apoptosis; Behavior, Animal; Bicuculline; Blotting, Western; Ca | 2014 |
GABAA/benzodiazepine receptor complex mediates the anxiolytic-like effect of Montanoa tomentosa.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Gene Expr | 2015 |
The lateral septum as a regulator of hippocampal theta oscillations and defensive behavior in rats.
Topics: Animals; Anxiety; Defense Mechanisms; GABA Agonists; GABA Antagonists; Hippocampus; Male; Muscimol; | 2015 |
[Behavior of high- and low-anxiety rats after modulation of GABAergic transmission in basolateral amygdala].
Topics: Aggression; Animals; Anxiety; Basolateral Nuclear Complex; Bicuculline; Functional Laterality; GABA | 2014 |
Activation of GABA-A receptors during postnatal brain development increases anxiety- and depression-related behaviors in a time- and dose-dependent manner in adult mice.
Topics: Animals; Animals, Newborn; Anxiety; Bicuculline; Brain; Corticosterone; Depression; Dose-Response Re | 2015 |
The role of CA3 GABAA receptors on anxiolytic-like behaviors and avoidance memory deficit induced by NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Avoidance Learning; Bicuculline; CA3 Region, Hippocam | 2016 |
Toll-Like Receptor 4 Deficiency Causes Reduced Exploratory Behavior in Mice Under Approach-Avoidance Conflict.
Topics: Analysis of Variance; Animals; Anxiety; Avoidance Learning; Baclofen; Disease Models, Animal; Explor | 2016 |
Involvement of glutamatergic N-methyl-d-aspartate receptors in the expression of increased head-dipping behaviors in the hole-board tests of olfactory bulbectomized mice.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dizocilpine Maleate; Excita | 2016 |
The lateral septum and anterior hypothalamus act in tandem to regulate burying in the shock-probe test but not open-arm avoidance in the elevated plus-maze.
Topics: Animals; Anxiety; Behavior, Animal; Exploratory Behavior; GABA Agonists; Hypothalamic Area, Lateral; | 2016 |
Amygdala selectively modulates defensive responses evoked from the superior colliculus in non-human primates.
Topics: Amygdala; Animals; Anxiety; Bicuculline; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonis | 2016 |
Differential contribution of dorsal and ventral hippocampus to trace and delay fear conditioning.
Topics: Acoustic Stimulation; Animals; Anxiety; Avoidance Learning; Conditioning, Psychological; Fear; GABA | 2009 |
Effect of intra-amygdala injection of nicotine and GABA receptor agents on anxiety-like behaviour in rats.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; GABA Ag | 2008 |
Medial prefrontal cortical activation modulates the impact of controllable and uncontrollable stressor exposure on a social exploration test of anxiety in the rat.
Topics: Animals; Anxiety; Behavior, Animal; Electroshock; Escape Reaction; Exploratory Behavior; Helplessnes | 2009 |
Possible GABAergic mechanism in the protective effect of allopregnenolone against immobilization stress.
Topics: Animals; Anxiety; Behavior, Animal; GABA Agents; Immobilization; Mice; Muscimol; Oxidative Stress; P | 2009 |
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumaze | 2008 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Fem | 2009 |
GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Bicuculline; Clonixin; Co | 2010 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Ac | 2011 |
Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Autoradiography; Brain; Female; Flunitrazepam; GABA-A Recepto | 2011 |
The effects of hippocampal opioidergic and septal GABAergic system interactions on anxiety-like behavior in rats.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; CA1 Region, Hippocampal; GABA Agonists; GABA Antago | 2011 |
Effects of GABA ligands injected into the nucleus accumbens shell on fear/anxiety-like and feeding behaviours in food-deprived rats.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Eating; Fear; Feeding Behavior; Food Depr | 2012 |
Contribution of the rostral ventromedial medulla to post-anxiety induced hyperalgesia.
Topics: Animals; Anxiety; GABA-A Receptor Agonists; Hyperalgesia; Male; Medulla Oblongata; Muscimol; Pain Me | 2012 |
Involvement of the dorsomedial hypothalamus and the nucleus tractus solitarii in chronic cardiovascular changes associated with anxiety in rats.
Topics: Adrenal Glands; Animals; Anxiety; Baroreflex; Behavior, Animal; Blood Pressure; Dorsomedial Hypothal | 2013 |
Involvement of GABAergic system in regulation of the anxiolytic- and antidepressant-like effects of Scrophularia striata extract in rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Bicuculline; Brain; Depression; Diseas | 2013 |
Temporary inactivation of the bed nucleus of the stria terminalis but not of the amygdala blocks freezing induced by trimethylthiazoline, a component of fox feces.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Conditioning, Psychological; Fear; Feces; Foxes; GABA | 2003 |
Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics.
Topics: Anesthetics; Animals; Anxiety; Behavior, Animal; Bicuculline; Brain; Central Nervous System Depressa | 2003 |
The dorsal raphe nucleus exerts opposed control on generalized anxiety and panic-related defensive responses in rats.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learnin | 2003 |
Rat behavior in two models of anxiety and brain [3H]muscimol binding: pharmacological, correlation, and multifactor analysis.
Topics: Analysis of Variance; Animals; Anxiety; Autoradiography; Behavior, Animal; Binding Sites; Brain; Dis | 2003 |
Autoradiographic imaging of altered synaptic alphabetagamma2 and extrasynaptic alphabeta GABAA receptors in a genetic mouse model of anxiety.
Topics: Animals; Anxiety; Autoradiography; Azides; Benzodiazepines; Female; GABA Agonists; Male; Mice; Mice, | 2004 |
Inactivation of the medial prefrontal cortex with the GABAA receptor agonist muscimol increases open-arm activity in the elevated plus-maze and attenuates shock-probe burying in rats.
Topics: Animals; Anxiety; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; GABA Agonists; Male; | 2004 |
Serotonergic neurons in the median raphe nucleus regulate inhibitory avoidance but not escape behavior in the rat elevated T-maze test of anxiety.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learning; Carbolines; Escape Rea | 2005 |
Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats.
Topics: Adrenalectomy; Analysis of Variance; Anesthetics; Animals; Anxiety; Bicuculline; Caffeine; Central N | 2005 |
Anxiolytic-like actions of the hexane extract from leaves of Annona cherimolia in two anxiety paradigms: possible involvement of the GABA/benzodiazepine receptor complex.
Topics: Animals; Annona; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Disease Models, | 2006 |
GABAA and GABAB agonist microinjections into medial accumbens shell increase feeding and induce anxiolysis in an animal model of anxiety.
Topics: Analysis of Variance; Animals; Anxiety; Baclofen; Behavior, Animal; Disease Models, Animal; Dose-Res | 2007 |
Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats.
Topics: Adrenalectomy; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bicucu | 2007 |
GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug In | 2008 |
Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Bicuculline; Blood Pressure; GABA Agonists; GABA A | 1995 |
GABA receptors in the region of the dorsomedial hypothalamus of rats regulate anxiety in the elevated plus-maze test. II. Physiological measures.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Avoidance Learning; Bicuculline; Blood Pressure; H | 1993 |
GABA receptors in the region of the dorsomedial hypothalamus of rats regulate anxiety in the elevated plus-maze test. I. Behavioral measures.
Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Blood Pressure; Heart Rate; Hypothalamus, Middle; | 1993 |
Regulation of anxiety by GABAA receptors in the rat amygdala.
Topics: Amygdala; Animals; Anxiety; Bicuculline; Interpersonal Relations; Male; Muscimol; Picrotoxin; Rats; | 1995 |
Ro 15-4513 potentiates, instead of antagonizes, ethanol-induced sleep in mice exposed to small platform stress.
Topics: Animals; Anxiety; Azides; Benzodiazepines; Central Nervous System Depressants; Cerebellum; Chlorides | 1996 |
Neurons in amygdala mediate ear pinna vasoconstriction elicited by unconditioned salient stimuli in conscious rabbits.
Topics: Amygdala; Animals; Anxiety; Attention; Conditioning, Psychological; Consciousness; Ear, External; Fo | 2001 |
The interaction of morphine and gamma-aminobutyric acid (GABA)ergic systems in anxiolytic behavior: using mu-opioid receptor knockout mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Estrogens; Estrous Cycle; Female; GABA Agonists; GABA- | 2002 |
Diminished stress responses in the alcohol-sensitive ANT rat line.
Topics: Adrenal Glands; Animals; Anxiety; Benzodiazepinones; Brain Chemistry; Central Nervous System; Cortic | 1991 |
Central- and peripheral-type benzodiazepine receptors: similar regulation by stress and GABA receptor agonists.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain; Flunitrazepam | 1989 |
Behavioral differences in an elevated plus-maze: correlation between anxiety and decreased number of GABA and benzodiazepine receptors in mouse cerebral cortex.
Topics: Animals; Anxiety; Brain; Carbolines; Cerebral Cortex; Diazepam; Exploratory Behavior; Flunitrazepam; | 1988 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: punished barpressing.
Topics: Amobarbital; Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Bicuculline; Carbolines; Chlordiazepox | 1985 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: extinction and successive discrimination.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Chlordiazepoxide; Discrimination Learning | 1986 |
Low doses of muscimol produce anticonflict actions in the lateral septum of the rat.
Topics: Animals; Anxiety; Conflict, Psychological; Male; Muscimol; Rats; Rats, Inbred Strains | 1986 |