muscimol has been researched along with Anochlesia in 27 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Initially, it induced a catalepsy-like state lasting 96." | 1.34 | Alteration of behavior in mice by muscimol is associated with regional electroencephalogram synchronization. ( Tobler, I; Vyazovskiy, VV; Winsky-Sommerer, R, 2007) |
| "It was determined that the increase in catalepsy across days was not the result of conditioning after an initial exposure to muscimol." | 1.29 | Catalepsy induced by muscimol infused into the hypothalamus can be sensitized and is modulated by ovarian steroids. ( Kaufman, LC; McCarthy, MM; Pfaff, DW; Schwartz-Giblin, S, 1993) |
| " It is proposed that withdrawal after long-term administration of PHT reduces the sensitivity of a GABA receptor site not sensitive to bicuculline." | 1.27 | Subsensitivity to muscimol-induced catalepsy after long-term administration of phenytoin in rats. ( Botez, MI; Lalonde, R, 1985) |
| "The haloperidol catalepsy was strongly inhibited by administration of picrotoxin to the Vm while the morphine catalepsy remained unchanged after picrotoxin." | 1.27 | Thalamus as a relay station for catalepsy and rigidity. ( Kolasiewicz, W; Ossowska, K; Wolfarth, S, 1985) |
| "Bicuculline (50 ng) abolished the catalepsy evoked by muscimol (25 ng)." | 1.27 | Evidence for the independent role of GABA synapses of the zona incerta-lateral hypothalamic region in haloperidol-induced catalepsy. ( Ossowska, K; Wardas, J; Wolfarth, S, 1988) |
| "The potentiation of haloperidol-induced catalepsy by GABA mimetics is also observed with dipropylacetate, delta-aminovaleric acid and gamma-acetylenic GABA." | 1.26 | Biphasic effects of direct, but not indirect, GABA mimetics and antagonists on haloperidol-induced catalepsy. ( Lloyd, KG; Worms, P, 1980) |
| "Gabaculine also induced catalepsy of medium intensity and potentiated the effect of haloperidol 24h after injection, when GABA was increased in the globus pallidus as well as in the substantia nigra." | 1.26 | Cataleptic and anticataleptic effects of muscimol and gabaculine injected into globus pallidus and substantia nigra, and interactions with haloperidol or benzodiazepines. ( Kamioka, T; Matsui, Y, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (70.37) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vyazovskiy, VV | 1 |
| Tobler, I | 1 |
| Winsky-Sommerer, R | 1 |
| Reavill, C | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
| Turski, L | 2 |
| Havemann, U | 1 |
| Kuschinsky, K | 1 |
| Ossowska, K | 4 |
| Wedzony, K | 1 |
| Wolfarth, S | 5 |
| Naik, SR | 1 |
| Kelkar, MR | 1 |
| Amladi, SR | 1 |
| Sheth, UK | 1 |
| Scheel-Krüger, J | 2 |
| Magelund, G | 1 |
| Olianas, M | 1 |
| Worms, P | 2 |
| Lloyd, KG | 2 |
| Karcz-Kubicha, M | 1 |
| Wardas, J | 2 |
| Krezołek, A | 1 |
| Wickens, AP | 1 |
| Pertwee, RG | 2 |
| McCarthy, MM | 1 |
| Kaufman, LC | 1 |
| Pfaff, DW | 1 |
| Schwartz-Giblin, S | 1 |
| Capasso, A | 1 |
| Biondi, A | 1 |
| Palagiano, F | 1 |
| Bonina, FP | 1 |
| Montenegro, L | 1 |
| de Caprariis, P | 1 |
| Pistorio, E | 1 |
| Sorrentino, L | 1 |
| Kaur, S | 1 |
| Ozer, H | 1 |
| Starr, M | 1 |
| Klusa, V | 1 |
| Germane, S | 1 |
| Svirskis, S | 1 |
| Opmane, B | 1 |
| Wikberg, JE | 1 |
| Matsui, Y | 2 |
| Kamioka, T | 2 |
| Moroni, F | 1 |
| Cheney, DL | 1 |
| Peralta, E | 1 |
| Costa, E | 1 |
| Depoortere, H | 1 |
| Di Chiara, G | 1 |
| Morelli, M | 1 |
| Porceddu, ML | 1 |
| Gessa, GL | 1 |
| Tirelli, E | 1 |
| Jodogne, C | 1 |
| Perikel, JJ | 1 |
| Greentree, SG | 1 |
| Swift, PA | 1 |
| Ogren, SO | 1 |
| Fuxe, K | 1 |
| Lalonde, R | 1 |
| Botez, MI | 1 |
| Kolasiewicz, W | 1 |
| Vrijmoed-de Vries, MC | 1 |
| Tönissen, H | 1 |
| Cools, AR | 1 |
| Klockgether, T | 1 |
| Schwarz, M | 1 |
| Sontag, KH | 1 |
1 review available for muscimol and Anochlesia
| Article | Year |
|---|---|
The role of GABA in the basal ganglia and limbic system for behaviour.
Topics: Animals; Basal Ganglia; Behavior, Animal; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Globu | 1981 |
26 other studies available for muscimol and Anochlesia
| Article | Year |
|---|---|
Alteration of behavior in mice by muscimol is associated with regional electroencephalogram synchronization.
Topics: Analysis of Variance; Animals; Behavior, Animal; Catalepsy; Cerebral Cortex; Cortical Synchronizatio | 2007 |
Gamma-aminobutyric acid and basal ganglia outflow pathways.
Topics: Animals; Basal Ganglia; Catalepsy; Disease Models, Animal; gamma-Aminobutyric Acid; Haloperidol; Hum | 1984 |
GABAergic mechanisms in mediating muscular rigidity, catalepsy and postural asymmetry in rats: differences between dorsal and ventral striatum.
Topics: Animals; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Muscle Rigidit | 1984 |
The role of the GABA mechanisms of the globus pallidus in mediating catalepsy, stereotypy and locomotor activity.
Topics: Animals; Bicuculline; Brain Mapping; Catalepsy; Drug Interactions; gamma-Aminobutyric Acid; Globus P | 1984 |
Effect of muscimol, a central GABA receptor agonist, on the catalepsy, striatal homovanillic acid increase, and analgesia induced by pilocarpine in rats.
Topics: Analgesics; Animals; Catalepsy; Corpus Striatum; Drug Interactions; Homovanillic Acid; Humans; Male; | 1981 |
Biphasic effects of direct, but not indirect, GABA mimetics and antagonists on haloperidol-induced catalepsy.
Topics: Allylglycine; Animals; Apomorphine; Behavior, Animal; Catalepsy; Drug Interactions; GABA Antagonists | 1980 |
Zona incerta-lateral hypothalamus as an output structure for impulses involved in neuroleptic drug-induced catalepsy.
Topics: Animals; Antipsychotic Agents; Bicuculline; Catalepsy; Corpus Striatum; Globus Pallidus; Hypothalami | 1993 |
delta 9-Tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats.
Topics: Amides; Animals; Arachidonic Acids; Catalepsy; Dronabinol; Drug Synergism; Endocannabinoids; Fatty A | 1993 |
Catalepsy induced by muscimol infused into the hypothalamus can be sensitized and is modulated by ovarian steroids.
Topics: Animals; Brain Mapping; Catalepsy; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Hypothalami | 1993 |
Anticonvulsive activity of a new GABA mimetic drug.
Topics: Analgesics; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Catalepsy; Convulsants; Dose-Re | 1997 |
MK 801 reverses haloperidol-induced catalepsy from both striatal and extrastriatal sites in the rat brain.
Topics: Animals; Antipsychotic Agents; Catalepsy; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists | 1997 |
The gamma(2)-MSH peptide mediates a central analgesic effect via a GABA-ergic mechanism that is independent from activation of melanocortin receptors.
Topics: alpha-MSH; Analgesics; Animals; Bicuculline; Catalepsy; Central Nervous System Depressants; Diazepam | 2001 |
Cataleptic and anticataleptic effects of muscimol and gabaculine injected into globus pallidus and substantia nigra, and interactions with haloperidol or benzodiazepines.
Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Anxiety Agents; Benzodiazepines; Catalepsy; Corpus Stria | 1978 |
Opiate receptor agonists as modulators of gamma-aminobutyric acid turnover in the nucleus caudatus, globus pallidus and substantia nigra of the rat.
Topics: Animals; Catalepsy; Caudate Nucleus; Endorphins; gamma-Aminobutyric Acid; Globus Pallidus; Humans; M | 1978 |
Neuropharmacological spectrum of muscimol.
Topics: Animals; Anticonvulsants; Catalepsy; Drug Interactions; gamma-Aminobutyric Acid; Humans; Male; Mice; | 1979 |
Effects of intracerebral injection with muscimol on locomotor activity and catalepsy in rats.
Topics: Animals; Catalepsy; Humans; Injections, Intraventricular; Locomotion; Male; Muscimol; Oxazoles; Rats | 1979 |
Role of thalamic gamma-aminobutyrate in motor functions: catalepsy and ipsiversive turning after intrathalamic muscimol.
Topics: Animals; Brain Mapping; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Motor Act | 1979 |
Adult-like biphasic neurobehavioral changes induced by a GABA-A agonist in infant and weanling mice.
Topics: Aging; Animals; Animals, Newborn; Ataxia; Behavior, Animal; Catalepsy; Dose-Response Relationship, D | 1991 |
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazen | 1988 |
D1- and D2-receptor antagonists induce catalepsy via different efferent striatal pathways [corrected].
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Catalepsy; Corpus | 1988 |
Subsensitivity to muscimol-induced catalepsy after long-term administration of phenytoin in rats.
Topics: Animals; Bicuculline; Catalepsy; Drug Interactions; Humans; Male; Muscimol; Oxazoles; Phenytoin; Rat | 1985 |
Thalamus as a relay station for catalepsy and rigidity.
Topics: Animals; Brain Mapping; Catalepsy; Escape Reaction; Haloperidol; Male; Morphine; Muscimol; Muscle Ri | 1985 |
Dopamine-GABA interactions: evidence that GABA transmits, modulates and mediates dopaminergic functions in the basal ganglia and the limbic system.
Topics: Amygdala; Animals; Basal Ganglia; Behavior, Animal; Benzodiazepines; Catalepsy; Corpus Striatum; Dop | 1986 |
The relationship between hindlimb disturbances, forelimb disturbances and catalepsy after increasing doses of muscimol injected into the striatal-pallidal complex.
Topics: Animals; Bicuculline; Catalepsy; Corpus Striatum; Forelimb; gamma-Aminobutyric Acid; Globus Pallidus | 1987 |
Evidence for the independent role of GABA synapses of the zona incerta-lateral hypothalamic region in haloperidol-induced catalepsy.
Topics: Animals; Bicuculline; Catalepsy; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haloperi | 1988 |
Rigidity and catalepsy after injections of muscimol into the ventromedial thalamic nucleus: an electromyographic study in the rat.
Topics: Animals; Bicuculline; Catalepsy; Electromyography; Humans; Male; Muscimol; Muscle Rigidity; Oxazoles | 1985 |