muscimol has been researched along with Amnesia in 13 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study investigated the possible relation between muscimol-induced long-term depression and barbiturates/benzodiazepine-induced amnesia and attempts to determine the possible effect of pregnenolone sulfate on muscimol-induced long-term depression." | 7.70 | Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. ( Akhondzadeh, S; Stone, TW, 1998) |
| "The role of cholinergic and GABAergic neuronal systems on the cycloheximide (CXM)-induced amnesia was investigated using the step-down-type passive avoidance task in mice." | 7.67 | Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice. ( Itoh, K; Kameyama, T; Nabeshima, T; Noda, Y, 1988) |
| "Post-training and/or pre-test 8-OH-DPAT, AS19 and muscimol induced amnesia." | 3.91 | Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus. ( Jafari-Sabet, M; Nemati, S; Torab, M, 2019) |
| " The present study investigated the possible relation between muscimol-induced long-term depression and barbiturates/benzodiazepine-induced amnesia and attempts to determine the possible effect of pregnenolone sulfate on muscimol-induced long-term depression." | 3.70 | Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. ( Akhondzadeh, S; Stone, TW, 1998) |
| "The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (DM-9384), a cyclic derivative of GABA, were investigated and compared with those of aniracetam in an animal model of amnesia, using a passive avoidance task with animals that have GABAergic neuronal dysfunctions." | 3.68 | Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions. ( Itoh, J; Kameyama, T; Nabeshima, T; Noda, Y; Tohyama, K, 1990) |
| "The role of cholinergic and GABAergic neuronal systems on the cycloheximide (CXM)-induced amnesia was investigated using the step-down-type passive avoidance task in mice." | 3.67 | Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice. ( Itoh, K; Kameyama, T; Nabeshima, T; Noda, Y, 1988) |
| "The muscimol response was compounded with the decreased levels of BDNF and c-Fos in the PFC and the hippocampus." | 1.72 | Post-Weaning Treatment with Probiotic Inhibited Stress-Induced Amnesia in Adulthood Rats: The Mediation of GABAergic System and BDNF/c-Fos Signaling Pathways. ( Alijanpour, S; Alizadeh, K; Golbabaei, A; Moghimi, H; Rezayof, A, 2022) |
| " The improving effects of huperzine A exhibited a bell-shaped dose-response curve." | 1.31 | Huperzine A reverses scopolamine- and muscimol-induced memory deficits in chick. ( Gao, Y; Guan, LC; Kuang, PZ; Tang, XC, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Alizadeh, K | 1 |
| Moghimi, H | 1 |
| Golbabaei, A | 1 |
| Alijanpour, S | 1 |
| Rezayof, A | 2 |
| Jafari-Sabet, M | 1 |
| Nemati, S | 1 |
| Torab, M | 1 |
| Hasanein, P | 1 |
| Sharifi, M | 1 |
| Farahmandfar, M | 1 |
| Akbarabadi, A | 1 |
| Bakhtazad, A | 1 |
| Zarrindast, MR | 2 |
| Disorbo, A | 1 |
| Wilson, GN | 1 |
| Bacik, S | 1 |
| Hoxha, Z | 1 |
| Biada, JM | 1 |
| Mickley, GA | 1 |
| Sparks, FT | 1 |
| Lehmann, H | 1 |
| Sutherland, RJ | 1 |
| Nazari-Serenjeh, F | 1 |
| Wang, SH | 1 |
| Finnie, PS | 1 |
| Hardt, O | 1 |
| Nader, K | 1 |
| Ishihara, S | 1 |
| Hiramatsu, M | 1 |
| Kameyama, T | 3 |
| Nabeshima, T | 3 |
| Akhondzadeh, S | 1 |
| Stone, TW | 1 |
| Gao, Y | 1 |
| Tang, XC | 1 |
| Guan, LC | 1 |
| Kuang, PZ | 1 |
| Noda, Y | 2 |
| Tohyama, K | 1 |
| Itoh, J | 1 |
| Itoh, K | 1 |
13 other studies available for muscimol and Amnesia
| Article | Year |
|---|---|
Post-Weaning Treatment with Probiotic Inhibited Stress-Induced Amnesia in Adulthood Rats: The Mediation of GABAergic System and BDNF/c-Fos Signaling Pathways.
Topics: Amnesia; Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Hippocampus; Male; Muscimol | 2022 |
Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Avoidance Learning; CA1 Region, Hippocampa | 2019 |
GABA(A) receptors in the central amygdala are involved in memory retention deficits induced by cannabinoids in rats.
Topics: Amnesia; Animals; Avoidance Learning; Benzoxazines; Bicuculline; Cannabinoids; Central Amygdaloid Nu | 2015 |
Recovery from ketamine-induced amnesia by blockade of GABA-A receptor in the medial prefrontal cortex of mice.
Topics: Amnesia; Animals; Baclofen; Bicuculline; Catheters, Indwelling; Dose-Response Relationship, Drug; Ex | 2017 |
Time-dependent retrograde amnesic effects of muscimol on conditioned taste aversion extinction.
Topics: Amnesia; Animals; Avoidance Learning; Conditioning, Classical; GABA Agonists; Male; Muscimol; Rats; | 2009 |
Between-systems memory interference during retrieval.
Topics: Amnesia; Animals; Conditioning, Classical; Fear; Female; GABA-A Receptor Agonists; Hippocampus; Male | 2011 |
Functional correlation between GABAergic and dopaminergic systems of dorsal hippocampus and ventral tegmental area in passive avoidance learning in rats.
Topics: Amnesia; Animals; Avoidance Learning; Benzazepines; Dopamine Antagonists; Dopaminergic Neurons; Dose | 2011 |
Dorsal hippocampus is necessary for novel learning but sufficient for subsequent similar learning.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Animals; Anisomycin; Calcium Channel Blockers; Conditioning, C | 2012 |
Development of tolerance to amnesic effects of chlordiazepoxide in relation to GABAergic and cholinergic neuronal systems.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Brain Chemistry; Chlordiazepoxide; Drug Tolerance | 1993 |
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.
Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Syn | 1998 |
Huperzine A reverses scopolamine- and muscimol-induced memory deficits in chick.
Topics: Alkaloids; Amnesia; Animals; Avoidance Learning; Chickens; Cholinesterase Inhibitors; GABA Agonists; | 2000 |
Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; gamma-Aminobutyric | 1990 |
Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice.
Topics: Amnesia; Animals; Avoidance Learning; Baclofen; Bicuculline; Butylscopolammonium Bromide; Cyclohexim | 1988 |