muscimol has been researched along with Aging in 71 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Muscimol treatment did not modify any of the parameters evaluated." | 5.38 | Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation. ( De Blas, M; Garrido, P; Giné, E; Mora, F; Santos, Á, 2012) |
| "Muscimol doses were 0." | 5.28 | Ontogeny of muscimol effects on locomotor activity, habituation, and pain reactivity in mice. ( Alleva, E; Laviola, G, 1990) |
| " Here we used muscimol to deactivate V1 while optically imaging visually evoked activity in MT in two primates, owl monkeys and galagos, where MT is exposed on the brain surface." | 3.73 | Optical imaging of visually evoked responses in the middle temporal area after deactivation of primary visual cortex in adult primates. ( Casagrande, VA; Collins, CE; Kaas, JH; Kaskan, PM; Khaytin, I; Xu, X, 2005) |
| "Brain aging decreases binding of tert-butylbicyclophosphorothionate (TBPS), a specific ligand for Cl- channels, but has no effect on Cl- influx." | 3.69 | Age-related changes of GABA-activated chloride channel properties in brain cortex synaptic plasma membrane: evidence for phospholipase involvement. ( Samochocki, M; Strosznajder, J, 1994) |
| "Muscimol treatment did not modify any of the parameters evaluated." | 1.38 | Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation. ( De Blas, M; Garrido, P; Giné, E; Mora, F; Santos, Á, 2012) |
| "As propofol is a GABAA agonist, we hypothesized that it and more specific GABAA modulators would increase intracellular free calcium ([Ca2+]i), resulting in the death of neonatal rat hippocampal neurons." | 1.35 | GABAergic mechanism of propofol toxicity in immature neurons. ( Fiskum, G; Kahraman, S; McCarthy, MM; Zup, SL, 2008) |
| "Some victims of sudden infant death syndrome have arcuate nucleus abnormalities." | 1.31 | Muscimol dialysis in the rostral ventral medulla reduced the CO(2) response in awake and sleeping piglets. ( Curran, AK; Darnall, RA; Filiano, JJ; Li, A; Nattie, EE, 2001) |
| "[3H]Muscimol binding was the highest in the cerebellum, and decreased in many brain regions in aged rats." | 1.30 | Effects of chronic treatment with a cyclic AMP-selective phosphodiesterase inhibitor, rolipram, on excitatory amino acid neurotransmission systems in young and aged rat brains. ( Araki, T; Chen, T; Hiranuma, T; Itoyama, Y; Kato, H; Kogure, K; Liu, XH; Murase, K, 1997) |
| "Muscimol responses were found to be sensitive to bicuculline, suggesting that they are mediated by GABAA receptors." | 1.30 | GABAA receptor agonists modulate K+ currents in adult hippocampal glial cells in situ. ( Bekar, LK; Jabs, R; Walz, W, 1999) |
| "[3H]muscimol binding was examined after various survival times up to 60 days." | 1.29 | Reduction of GABAA receptor binding of [3H]muscimol in the barrel field of mice after peripheral denervation: transient and long-lasting effects. ( Głazewski, S; Jabłońska, B; Kossut, M; Siucińska, E; Skangiel-Kramska, J, 1994) |
| "We investigated the effects of the long-term administration of Kamikihito (KKT) on the specific binding of [3H]muscimol and [3H]flunitrazepam in the brains of young and aged rats using in vitro quantitative autoradiography." | 1.29 | Effects of Kamikihito, a traditional Chinese medicine, on neurotransmitter receptor binding in the aged rat brain determined by in vitro autoradiography (2): changes in GABAA and benzodiazepine receptor binding. ( Hasegawa, T; Hayashi, T; Ishihara, S; Kameyama, T; Kaneyuki, T; Morimasa, T; Nabeshima, T; Shohmori, T; Yamada, K, 1994) |
| " In aged rats, the dose-response curve was shifted to the left, indicating an increase in the potency of GABA to inhibit [3H]t-butylbicycloorthobenzoate binding." | 1.29 | GABAA receptor binding in the aging rat inferior colliculus. ( Albin, RL; Caspary, DM; Milbrandt, JC; Turgeon, SM, 1996) |
| "Phenobarbital (PhB) was administered to pregnant mice during days 9-18 of gestation." | 1.28 | Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors. ( Fares, F; Gavish, M; Pick, CG; Weizman, A; Yanai, J, 1990) |
| "Muscimol doses were 0." | 1.28 | Ontogeny of muscimol effects on locomotor activity, habituation, and pain reactivity in mice. ( Alleva, E; Laviola, G, 1990) |
| "Taurine was thus able to modulate GABA release through bicuculline-sensitive receptors, but this modulation was not evident in cerebellar slices from 7-day-old mice." | 1.28 | Release of taurine and GABA from cerebellar slices from developing and adult mice. ( Kontro, P; Oja, SS, 1989) |
| "Muscimol pretreatment (dosages ranging from 0." | 1.27 | Ontogeny of GABA-ergic and dopaminergic mediation of gnawing behavior in the mouse. ( Tirelli, E, 1987) |
| "[3H]muscimol was used for the labeling of GABA receptors and [3H]flunitrazepam for benzodiazepine receptors." | 1.26 | Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study. ( Kuhar, MJ; Palacios, JM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (21.13) | 18.7374 |
| 1990's | 38 (53.52) | 18.2507 |
| 2000's | 17 (23.94) | 29.6817 |
| 2010's | 1 (1.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahraman, S | 1 |
| Zup, SL | 1 |
| McCarthy, MM | 1 |
| Fiskum, G | 1 |
| Freeman, JH | 1 |
| Campolattaro, MM | 1 |
| Yoshida, M | 1 |
| Satoh, T | 1 |
| Nakamura, KC | 1 |
| Kaneko, T | 1 |
| Hata, Y | 2 |
| Garrido, P | 1 |
| De Blas, M | 1 |
| Giné, E | 1 |
| Santos, Á | 1 |
| Mora, F | 1 |
| Ichisaka, S | 1 |
| Katoh-Semba, R | 1 |
| Ohshima, M | 1 |
| Kameyama, K | 1 |
| Tsumoto, T | 1 |
| Miller, G | 1 |
| Leventhal, AG | 1 |
| Wang, Y | 1 |
| Pu, M | 1 |
| Zhou, Y | 1 |
| Ma, Y | 1 |
| Alonso, G | 1 |
| Runquist, M | 1 |
| Hussy, N | 1 |
| Duvoid, A | 1 |
| Moos, F | 1 |
| Coppola, JD | 1 |
| Horwitz, BA | 1 |
| Hamilton, J | 1 |
| Blevins, JE | 1 |
| McDonald, RB | 1 |
| Collins, CE | 1 |
| Xu, X | 1 |
| Khaytin, I | 1 |
| Kaskan, PM | 1 |
| Casagrande, VA | 1 |
| Kaas, JH | 1 |
| Frye, CA | 1 |
| Sumida, K | 1 |
| Lydon, JP | 1 |
| O'Malley, BW | 1 |
| Pfaff, DW | 1 |
| Bay, KD | 1 |
| Beck, P | 1 |
| Skinner, RD | 1 |
| Garcia-Rill, E | 1 |
| Lippa, AS | 1 |
| Critchett, DJ | 1 |
| Ehlert, F | 1 |
| Yamamura, HI | 1 |
| Enna, SJ | 1 |
| Bartus, RT | 1 |
| Seth, PK | 1 |
| Chandra, SV | 1 |
| East, JM | 1 |
| Dutton, GR | 1 |
| Palacios, JM | 1 |
| Kuhar, MJ | 1 |
| Acs, Z | 1 |
| Makara, GB | 1 |
| Stark, E | 1 |
| Brooksbank, BW | 1 |
| Atkinson, DJ | 1 |
| Balázs, R | 2 |
| Patel, AJ | 1 |
| Smith, RM | 1 |
| Kingsbury, AE | 1 |
| Hunt, A | 1 |
| Skangiel-Kramska, J | 1 |
| Głazewski, S | 1 |
| Jabłońska, B | 1 |
| Siucińska, E | 1 |
| Kossut, M | 1 |
| Yamada, K | 1 |
| Hayashi, T | 1 |
| Hasegawa, T | 1 |
| Ishihara, S | 1 |
| Kameyama, T | 1 |
| Morimasa, T | 1 |
| Kaneyuki, T | 1 |
| Shohmori, T | 1 |
| Nabeshima, T | 1 |
| Samochocki, M | 2 |
| Strosznajder, J | 2 |
| Gutiérrez, A | 1 |
| Khan, ZU | 1 |
| Morris, SJ | 1 |
| De Blas, AL | 1 |
| Szwarcfarb, B | 2 |
| Carbone, S | 2 |
| Stein, ML | 1 |
| Medina, J | 1 |
| Moguilevsky, JA | 2 |
| Ruano, D | 3 |
| Machado, A | 2 |
| Vitorica, J | 3 |
| Araki, T | 3 |
| Kato, H | 3 |
| Kanai, Y | 1 |
| Kogure, K | 2 |
| Taira, T | 1 |
| Uusi-Oukari, M | 1 |
| Korpi, ER | 1 |
| Lim, JY | 1 |
| Utzschneider, DA | 1 |
| Sakatani, K | 1 |
| Kocsis, JD | 1 |
| Milbrandt, JC | 1 |
| Albin, RL | 1 |
| Turgeon, SM | 1 |
| Caspary, DM | 1 |
| Fujiwara, T | 1 |
| Itoyama, Y | 2 |
| Benes, FM | 1 |
| Vincent, SL | 1 |
| Marie, A | 1 |
| Khan, Y | 1 |
| Araujo, F | 1 |
| Bentareha, R | 1 |
| Mitsushima, D | 1 |
| Kimura, F | 1 |
| Obata, K | 1 |
| Chen, T | 1 |
| Liu, XH | 1 |
| Hiranuma, T | 1 |
| Murase, K | 1 |
| Borodinsky, LN | 1 |
| Pesce, G | 1 |
| Pomata, P | 1 |
| Fiszman, ML | 2 |
| Clark, AS | 1 |
| Robinson, S | 1 |
| Henderson, LP | 1 |
| Lo, YJ | 1 |
| Rao, SC | 1 |
| Sanes, DH | 1 |
| Fuchs, JL | 1 |
| Salazar, E | 1 |
| Roth, C | 1 |
| Leonhardt, S | 1 |
| Theiling, K | 1 |
| Lakomek, M | 1 |
| Jarry, H | 1 |
| Wuttke, W | 2 |
| Martin, JH | 1 |
| Kably, B | 1 |
| Hacking, A | 1 |
| Bekar, LK | 1 |
| Jabs, R | 1 |
| Walz, W | 1 |
| Curran, AK | 1 |
| Darnall, RA | 1 |
| Filiano, JJ | 1 |
| Li, A | 1 |
| Nattie, EE | 1 |
| Grobin, AC | 1 |
| Matthews, DB | 1 |
| Montoya, D | 1 |
| Wilson, WA | 1 |
| Morrow, AL | 1 |
| Swartzwelder, HS | 1 |
| Boller, M | 1 |
| Schmidt, M | 1 |
| Velísková, J | 1 |
| Moshé, SL | 4 |
| Him, A | 1 |
| Johnston, AR | 1 |
| Yau, JL | 1 |
| Seckl, J | 1 |
| Dutia, MB | 1 |
| Silveri, MM | 1 |
| Spear, LP | 1 |
| Sperber, EF | 3 |
| Brown, LL | 1 |
| Tempel, A | 2 |
| Xia, Y | 1 |
| Haddad, GG | 1 |
| Erdö, SL | 2 |
| Meyer, DL | 1 |
| Malz, CR | 1 |
| Hofmann, MH | 1 |
| Ebbesson, SO | 1 |
| Shaw, C | 3 |
| Lanius, RA | 1 |
| Scarth, BA | 1 |
| Veruki, ML | 1 |
| Yeh, HH | 1 |
| Cameron, L | 1 |
| March, D | 1 |
| Cynader, M | 1 |
| Zielinski, B | 1 |
| Hendrickson, A | 1 |
| Tirelli, E | 2 |
| Jodogne, C | 1 |
| Perikel, JJ | 1 |
| Cano, J | 1 |
| Mollace, V | 1 |
| De Francesco, EA | 1 |
| Fersini, G | 1 |
| Nistico, G | 1 |
| Fares, F | 1 |
| Weizman, A | 1 |
| Pick, CG | 1 |
| Yanai, J | 1 |
| Gavish, M | 1 |
| Novotny, EA | 1 |
| Lange, GD | 1 |
| Barker, JL | 1 |
| Laviola, G | 1 |
| Alleva, E | 1 |
| Caboche, J | 1 |
| Mitrovic, N | 1 |
| Le Saux, F | 1 |
| Besson, MJ | 1 |
| Sauter, A | 1 |
| Maurin, Y | 1 |
| Wolff, JR | 1 |
| Kontro, P | 1 |
| Oja, SS | 1 |
| Ito, Y | 1 |
| Ho, IK | 1 |
| Hoskins, B | 1 |
| Wurpel, JN | 2 |
| Flügge, G | 1 |
| Fuchs, E | 1 |
| Sharpless, NS | 1 |
71 other studies available for muscimol and Aging
| Article | Year |
|---|---|
GABAergic mechanism of propofol toxicity in immature neurons.
Topics: Aging; Anesthetics, Intravenous; Animals; Calcium; Calcium Channel Agonists; Calcium Channels, L-Typ | 2008 |
Ontogenetic change in the auditory conditioned stimulus pathway for eyeblink conditioning.
Topics: Acoustic Stimulation; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Auditory | 2008 |
Cortical activity regulates corticothalamic synapses in dorsal lateral geniculate nucleus of rats.
Topics: Aging; Animals; Early Growth Response Protein 1; Geniculate Bodies; Immunoenzyme Techniques; Immunoh | 2009 |
Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation.
Topics: Aging; Analysis of Variance; Animals; Avoidance Learning; Corticosterone; GABA Antagonists; GABA-A R | 2012 |
Activity-dependent change in the protein level of brain-derived neurotrophic factor but no change in other neurotrophins in the visual cortex of young and adult ferrets.
Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Ferrets; Muscimol; Nerve Growth Factors; Protein | 2003 |
Neuroscience. Old neurons revisit their youth.
Topics: Aging; Animals; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Macaca; Muscimol; Neurons; | 2003 |
GABA and its agonists improved visual cortical function in senescent monkeys.
Topics: Aging; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Macaca fascic | 2003 |
Age-related modifications of the morphological organization of pituicytes are associated with alteration of the GABAergic and dopaminergic innervation afferent to the neurohypophysial lobe.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Afferent Pathways; Aging; Animals; Astro | 2003 |
Reduced feeding response to muscimol and neuropeptide Y in senescent F344 rats.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Appetite Stimulants; Body Weight; Drug Interactions; Eati | 2005 |
Optical imaging of visually evoked responses in the middle temporal area after deactivation of primary visual cortex in adult primates.
Topics: Aging; Animals; Aotidae; Diagnostic Imaging; Evoked Potentials, Visual; Galago; Muscimol; Superior C | 2005 |
Mid-aged and aged wild-type and progestin receptor knockout (PRKO) mice demonstrate rapid progesterone and 3alpha,5alpha-THP-facilitated lordosis.
Topics: Aging; Animals; Desoxycorticosterone; Estradiol; Female; GABA Agonists; Injections, Intravenous; Inj | 2006 |
GABAergic modulation of developing pedunculopontine nucleus.
Topics: Action Potentials; Aging; Animals; Baclofen; GABA Agonists; GABA-B Receptor Antagonists; gamma-Amino | 2007 |
Age-related alterations in neurotransmitter receptors: an electrophysiological and biochemical analysis.
Topics: Acetylcholine; Aging; Animals; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Ne | 1981 |
Neurotransmitters and neurotransmitter receptors in developing and adult rats during manganese poisoning.
Topics: Aging; Animals; Animals, Newborn; Biogenic Amines; Cerebellum; Haplorhini; Manganese Poisoning; Musc | 1984 |
The development of GABA receptors in normal and mutant mouse cerebellum.
Topics: Aging; Animals; Cerebellum; Mice; Mice, Neurologic Mutants; Muscimol; Receptors, Cell Surface; Recep | 1981 |
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
Topics: Aging; Animals; Autoradiography; Cerebellum; Clonazepam; Female; Flunitrazepam; gamma-Aminobutyric A | 1981 |
Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in vitro.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Diazepam; Female; GABA Antagonists; gamma-A | 1984 |
Biochemical development of the human brain. II. Some parameters of the GABA-ergic system.
Topics: Adult; Aging; Cerebellum; Cerebral Cortex; DNA; Female; gamma-Aminobutyric Acid; Gestational Age; Gl | 1981 |
Effects of thyroid state on brain development: muscarinic acetylcholine and GABA receptors.
Topics: Acetylcholine; Aging; Animals; Brain; Female; gamma-Aminobutyric Acid; Male; Muscimol; Quinuclidinyl | 1980 |
Reduction of GABAA receptor binding of [3H]muscimol in the barrel field of mice after peripheral denervation: transient and long-lasting effects.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Cerebral Cortex; Denervation; Mice; Muscimol; Neu | 1994 |
Effects of Kamikihito, a traditional Chinese medicine, on neurotransmitter receptor binding in the aged rat brain determined by in vitro autoradiography (2): changes in GABAA and benzodiazepine receptor binding.
Topics: Aging; Animals; Autoradiography; Brain Chemistry; Drugs, Chinese Herbal; Flunitrazepam; Image Proces | 1994 |
Age-related changes of GABA-activated chloride channel properties in brain cortex synaptic plasma membrane: evidence for phospholipase involvement.
Topics: Aging; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic | 1994 |
Age-related decrease of GABAA receptor subunits and glutamic acid decarboxylase in the rat inferior colliculus.
Topics: Aging; Animals; Glutamate Decarboxylase; Immunohistochemistry; In Situ Hybridization; Inferior Colli | 1994 |
Sexual differences in the effect of the GABAergic system on LH secretion and in the hypothalamic ontogenesis of GABAA receptors in prepubertal rats.
Topics: Aging; Aminooxyacetic Acid; Animals; Female; gamma-Aminobutyric Acid; Hypothalamus; Luteinizing Horm | 1994 |
Absence of modifications of the pharmacological properties of the GABAA receptor complex during aging, as assessed in 3- and 24-month-old rat cerebral cortex.
Topics: Affinity Labels; Aging; Animals; Anti-Anxiety Agents; Binding, Competitive; Cerebral Cortex; Flunitr | 1993 |
Modulatory action of arachidonic acid on GABAA/chloride channel receptor function in adult and aged brain cortex membranes.
Topics: Aging; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic | 1993 |
Selective changes of neurotransmitter receptors in middle-aged gerbil brain.
Topics: Adenosine; Aging; Animals; Autoradiography; Benzazepines; Brain; Dizocilpine Maleate; Gerbillinae; I | 1993 |
Early postnatal treatment with muscimol transiently alters brain GABAA receptors and open-field behavior in rat.
Topics: Aging; Animals; Animals, Newborn; Azides; Behavior, Animal; Benzodiazepines; Brain Chemistry; Ethano | 1993 |
The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve.
Topics: Action Potentials; Aging; Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Muscim | 1993 |
GABAA receptor binding in the aging rat inferior colliculus.
Topics: Aged; Aging; Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic | 1996 |
Regional age-related alterations in cholinergic and GABAergic receptors in the rat brain.
Topics: Aging; Animals; Autoradiography; Brain; Hemicholinium 3; Male; Muscimol; Quinuclidinyl Benzilate; Ra | 1996 |
Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Autoradiography; Female; Humans; Male; Middle Aged; Models, N | 1996 |
Age-related modifications on the GABAA receptor binding properties from Wistar rat prefrontal cortex.
Topics: Aging; Animals; Benzodiazepines; Binding Sites; Flunitrazepam; GABA Agonists; GABA Modulators; gamma | 1996 |
The maturation of GABA(A) receptor-mediated control of luteinizing hormone secretion in immature male rats.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; GABA Agonists; GABA Antagonists; Infusions, Intraveno | 1997 |
Excitatory and trophic action of GABA and related substances in newborn mice and organotypic cerebellar culture.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Calcium; Cell Count; Cerebellum; Diazepam; GABA Agent | 1997 |
Effects of chronic treatment with a cyclic AMP-selective phosphodiesterase inhibitor, rolipram, on excitatory amino acid neurotransmission systems in young and aged rat brains.
Topics: Aging; Animals; Aspartic Acid; Autoradiography; Brain; Brain Chemistry; Dizocilpine Maleate; Excitat | 1997 |
Neurosteroid modulation of GABAA receptors in the developing rat brain cortex.
Topics: Aging; Animals; Animals, Newborn; Cerebral Cortex; Embryo, Mammalian; Embryonic and Fetal Developmen | 1997 |
Dynamics of GABA(A) receptor binding in the ventromedial hypothalamus during postnatal development in the rat.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Female; Hippocampus; Male; Muscimol; Rats; Recept | 1997 |
Modulation of calcium by inhibitory systems in the developing auditory midbrain.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals | 1998 |
Effects of whisker trimming on GABA(A) receptor binding in the barrel cortex of developing and adult rats.
Topics: Aging; Animals; Autoradiography; Dizocilpine Maleate; Down-Regulation; Electron Transport Complex IV | 1998 |
Ontogeny of the GNRH-, glutaminase- and glutamate decarboxylase-gene expression in the hypothalamus of female rats.
Topics: Aging; Animals; Cerebral Ventricles; Enzyme-Linked Immunosorbent Assay; Exons; Female; Gene Expressi | 1998 |
Activity-dependent development of cortical axon terminations in the spinal cord and brain stem.
Topics: Aging; Animals; Animals, Newborn; Axons; Brain Stem; Cats; Cerebral Cortex; Molecular Probes; Motor | 1999 |
GABAA receptor agonists modulate K+ currents in adult hippocampal glial cells in situ.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Chlorides; Electric Conductivity; GABA Antagonists; G | 1999 |
Muscimol dialysis in the rostral ventral medulla reduced the CO(2) response in awake and sleeping piglets.
Topics: Aging; Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Carbon Dioxide; Dialysis; Humans; | 2001 |
Age-related differences in neurosteroid potentiation of muscimol-stimulated 36Cl(-) flux following chronic ethanol treatment.
Topics: Adolescent; Aging; Alcohol-Induced Disorders, Nervous System; Animals; Anti-Anxiety Agents; Brain; C | 2001 |
Postnatal maturation of GABA(A) and GABA(C) receptor function in the mammalian superior colliculus.
Topics: Aging; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentia | 2001 |
Sexual dimorphism and developmental regulation of substantia nigra function.
Topics: Aging; Animals; Animals, Newborn; Castration; Convulsants; Disease Susceptibility; Female; GABA Agon | 2001 |
Tonic activity and GABA responsiveness of medial vestibular nucleus neurons in aged rats.
Topics: Aging; Animals; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; | 2001 |
The effects of NMDA and GABAA pharmacological manipulations on ethanol sensitivity in immature and mature animals.
Topics: Age Factors; Aging; Animals; Central Nervous System Depressants; Dose-Response Relationship, Drug; E | 2002 |
Changes in the effect of gamma-aminobutyric acid on prolactin secretion during sexual maturation in female rats.
Topics: 4-Aminobutyrate Transaminase; Aging; Aminooxyacetic Acid; Animals; Baclofen; Female; gamma-Aminobuty | 1992 |
Age-dependent changes in substantia nigra GABA-mediated seizure suppression.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Dominance, Cerebral; Energy Metabolism; Flu | 1992 |
Ontogeny and distribution of GABAA receptors in rat brainstem and rostral brain regions.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Brain; Brain Stem; Muscimol; Organ Specificity; R | 1992 |
Changes in ligand binding to GABAA receptor sites in pacific salmon (Oncorhynchus) brain during spawning migration and "aging".
Topics: Aging; Aminobutyrates; Analgesics; Animals; Baclofen; Bicuculline; Binding, Competitive; Brain; Fema | 1992 |
Cortical AMPA receptors: age-dependent regulation by cellular depolarization and agonist stimulation.
Topics: Aging; Animals; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Male; Membrane Potentials; | 1992 |
Age-dependent regulation of GABAA receptors in neocortex.
Topics: Aging; Animals; Baclofen; Cats; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Aci | 1992 |
Vasoactive intestinal polypeptide modulates GABAA receptor function in bipolar cells and ganglion cells of the rat retina.
Topics: Aging; Animals; Animals, Newborn; Chloride Channels; Drug Synergism; Electric Conductivity; gamma-Am | 1992 |
Pre- and postnatal development of GABA receptors in Macaca monkey visual cortex.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Binding Sites; Corpus Striatum; Embryonic and Fetal Deve | 1991 |
Adult-like biphasic neurobehavioral changes induced by a GABA-A agonist in infant and weanling mice.
Topics: Aging; Animals; Animals, Newborn; Ataxia; Behavior, Animal; Catalepsy; Dose-Response Relationship, D | 1991 |
Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.
Topics: Aging; Animals; Binding Sites; Cerebellum; Cerebral Cortex; Culture Techniques; Drug Interactions; F | 1991 |
Age-dependent changes in cardiovascular responses induced by muscimol infused into the nucleus tractus solitarii and nucleus parabrachialis medialis in rats.
Topics: Aging; Animals; Bicuculline; Blood Pressure; Heart Rate; Hemodynamics; Injections; Male; Medulla Obl | 1991 |
Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors.
Topics: Aging; Animals; Brain; Female; Flunitrazepam; Male; Mice; Muscimol; Phenobarbital; Pregnancy; Prenat | 1990 |
Embryonic and early postnatal hippocampal cells respond to nanomolar concentrations of muscimol.
Topics: Aging; Animals; Animals, Newborn; Cell Separation; Embryo, Mammalian; Flow Cytometry; Fluorescent Dy | 1990 |
Ontogeny of muscimol effects on locomotor activity, habituation, and pain reactivity in mice.
Topics: Aging; Animals; Brain Chemistry; Female; Habituation, Psychophysiologic; Male; Mice; Motor Activity; | 1990 |
Postnatal evolution of the gamma-aminobutyric acid/benzodiazepine receptor complex in a model of inherited epilepsy: the quaking mouse.
Topics: Aging; Animals; Brain; Brain Stem; Cerebellum; Diazepam; Diencephalon; Epilepsy; Flunitrazepam; gamm | 1989 |
Age-related loss of t-[35S]butylbicyclophosphorothionate binding to the gamma-aminobutyric acidA receptor-coupled chloride ionophore in rat cerebral cortex.
Topics: Aging; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; B | 1989 |
Release of taurine and GABA from cerebellar slices from developing and adult mice.
Topics: Aging; Animals; Bicuculline; Cerebellum; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Kinet | 1989 |
Cerebellar GABAA and benzodiazepine receptor characteristics in young and aged mice.
Topics: Aging; Animals; Cerebellum; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Muscimol; Recepto | 1988 |
Ontogeny of GABA-ergic and dopaminergic mediation of gnawing behavior in the mouse.
Topics: Aging; Animals; Dopamine; Female; gamma-Aminobutyric Acid; Male; Methylphenidate; Mice; Muscimol; St | 1987 |
Age-related changes of muscimol binding in the substantia nigra.
Topics: Aging; Animals; Cerebellum; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Substantia Nigra | 1988 |
Postnatal development of transmitter systems: sexual differentiation of the GABAergic system and effects of muscimol.
Topics: Aging; Animals; Brain; Female; gamma-Aminobutyric Acid; Male; Maternal-Fetal Exchange; Muscimol; Pre | 1986 |
Age-related changes in striatal dopamine activity following nigral muscimol infusions.
Topics: Aging; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Injections; Muscimol; Neurons; Rats; Ra | 1987 |