muscimol has been researched along with Absence Status in 8 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigate whether microinjections of GABAergic agonists into the AN were protective against pilocarpine-induced generalized seizures and status epilepticus (SE)." | 7.76 | Microinjection of GABAergic agents into the anterior nucleus of the thalamus modulates pilocarpine-induced seizures and status epilepticus. ( Andrade, D; Bittencourt, S; Covolan, L; Dubiela, FP; Hamani, C; Lozano, A; Mello, LE; Queiroz, C, 2010) |
| "Functional modulation of gamma-aminobutyric acid(A) (GABA(A)) receptors by Zn(2+), pentobarbital, neuroactive steroid alphaxalone, and flunitrazepam was studied in the cerebral cortex and cerebellum of rats undergoing status epilepticus induced by pilocarpine." | 7.70 | Zinc inhibition of gamma-aminobutyric acid(A) receptor function is decreased in the cerebral cortex during pilocarpine-induced status epilepticus. ( Banerjee, PK; Olsen, RW; Snead, OC, 1999) |
| " We investigate whether microinjections of GABAergic agonists into the AN were protective against pilocarpine-induced generalized seizures and status epilepticus (SE)." | 3.76 | Microinjection of GABAergic agents into the anterior nucleus of the thalamus modulates pilocarpine-induced seizures and status epilepticus. ( Andrade, D; Bittencourt, S; Covolan, L; Dubiela, FP; Hamani, C; Lozano, A; Mello, LE; Queiroz, C, 2010) |
| " Two animal models of TLE--amygdala kindling and pilocarpine-induced status epilepticus (Pilo-SE)--were tested." | 3.75 | Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics. ( Leung, LS; Long, JJ; Luo, T; McMurran, TJ; Shen, B; Stewart, L, 2009) |
| "Functional modulation of gamma-aminobutyric acid(A) (GABA(A)) receptors by Zn(2+), pentobarbital, neuroactive steroid alphaxalone, and flunitrazepam was studied in the cerebral cortex and cerebellum of rats undergoing status epilepticus induced by pilocarpine." | 3.70 | Zinc inhibition of gamma-aminobutyric acid(A) receptor function is decreased in the cerebral cortex during pilocarpine-induced status epilepticus. ( Banerjee, PK; Olsen, RW; Snead, OC, 1999) |
| "Limbic status epilepticus was induced in awake, unrestrained rats by electrically stimulating the anterior piriform cortex or the basal amygdaloid nucleus for about 40 min." | 1.29 | The functional anatomy of limbic status epilepticus in the rat. II. The effects of focal deactivation. ( Price, JL; White, LE, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Long, JJ | 1 |
| Shen, B | 1 |
| Luo, T | 1 |
| Stewart, L | 1 |
| McMurran, TJ | 1 |
| Leung, LS | 1 |
| Bittencourt, S | 1 |
| Dubiela, FP | 1 |
| Queiroz, C | 1 |
| Covolan, L | 1 |
| Andrade, D | 1 |
| Lozano, A | 1 |
| Mello, LE | 1 |
| Hamani, C | 1 |
| López-Meraz, ML | 1 |
| Rocha, LL | 1 |
| Miquel, M | 1 |
| Ortega, JC | 1 |
| Perez-Estudillo, CA | 1 |
| García, LI | 1 |
| Hernandez, ME | 1 |
| Manzo, J | 1 |
| White, LE | 1 |
| Price, JL | 1 |
| Banerjee, PK | 1 |
| Olsen, RW | 1 |
| Snead, OC | 1 |
| Molnár, P | 1 |
| Nadler, JV | 1 |
| Moshé, SL | 1 |
| Sperber, EF | 1 |
| Brown, LL | 1 |
| Tempel, A | 1 |
| Lothman, EW | 1 |
| Bertram, EH | 1 |
| Kapur, J | 1 |
| Stringer, JL | 1 |
8 other studies available for muscimol and Absence Status
| Article | Year |
|---|---|
Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics.
Topics: Anesthetics, General; Animals; Brain; Consciousness Disorders; Convulsants; Disease Models, Animal; | 2009 |
Microinjection of GABAergic agents into the anterior nucleus of the thalamus modulates pilocarpine-induced seizures and status epilepticus.
Topics: Animals; Anterior Thalamic Nuclei; Bicuculline; Convulsants; Electroencephalography; GABA Agents; Hu | 2010 |
Amino acid tissue levels and GABAA receptor binding in the developing rat cerebellum following status epilepticus.
Topics: Alanine; Amino Acids; Animals; Cerebellum; Female; Glutamine; Male; Muscimol; Rats; Rats, Wistar; Re | 2012 |
The functional anatomy of limbic status epilepticus in the rat. II. The effects of focal deactivation.
Topics: Amygdala; Animals; Autoradiography; Brain; Carbon Radioisotopes; Deoxyglucose; Hippocampus; Lidocain | 1993 |
Zinc inhibition of gamma-aminobutyric acid(A) receptor function is decreased in the cerebral cortex during pilocarpine-induced status epilepticus.
Topics: Animals; Biological Transport; Cerebellum; Cerebral Cortex; Chlorides; GABA Agonists; GABA-A Recepto | 1999 |
Lack of effect of mossy fiber-released zinc on granule cell GABA(A) receptors in the pilocarpine model of epilepsy.
Topics: Action Potentials; Animals; Dendrites; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Amin | 2001 |
Age-dependent changes in substantia nigra GABA-mediated seizure suppression.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Dominance, Cerebral; Energy Metabolism; Flu | 1992 |
Recurrent spontaneous hippocampal seizures in the rat as a chronic sequela to limbic status epilepticus.
Topics: Action Potentials; Animals; Chronic Disease; Disease Models, Animal; Electric Stimulation; Electroen | 1990 |