muscimol has been researched along with Absence Seizure Disorder in 12 studies
Muscimol: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
muscimol : A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, using this method we examined the anatomical locations of muscimol-induced absence seizures in the rat forebrain." | 7.69 | Fos oncoprotein expression in the rat forebrain following muscimol-induced absence seizures. ( Ju, G; Le Gal La Salle, G; Ridoux, V; Yu, PH; Zhang, X, 1996) |
| " Here, using this method we examined the anatomical locations of muscimol-induced absence seizures in the rat forebrain." | 3.69 | Fos oncoprotein expression in the rat forebrain following muscimol-induced absence seizures. ( Ju, G; Le Gal La Salle, G; Ridoux, V; Yu, PH; Zhang, X, 1996) |
| "Muscimol infusion to inactivate the mid-septotemporal hippocampus, as compared to saline infusion, significantly decreased the peak frequency of the PDs induced by GBL, decreased 30-120 Hz hippocampal gamma power, and hastened the transition of PDs to 1-2 Hz slow waves." | 1.43 | The hippocampus participates in a pharmacological rat model of absence seizures. ( Arcaro, J; Chu, L; Kuo, M; Ma, J; Mirsattari, SM; Stan Leung, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ajaz, R | 1 |
| Mousavi, SR | 1 |
| Mirsattari, SM | 2 |
| Leung, LS | 1 |
| Arcaro, J | 1 |
| Ma, J | 1 |
| Chu, L | 1 |
| Kuo, M | 1 |
| Stan Leung, L | 1 |
| Riban, V | 1 |
| Pereira de Vasconcelos, A | 1 |
| Phâm-Lê, BT | 1 |
| Ferrandon, A | 1 |
| Marescaux, C | 5 |
| Nehlig, A | 1 |
| Depaulis, A | 6 |
| Vergnes, M | 4 |
| Micheletti, G | 1 |
| Rumbach, L | 1 |
| Warter, JM | 1 |
| Snead, OC | 3 |
| Liu, CC | 1 |
| Zhang, X | 1 |
| Le Gal La Salle, G | 1 |
| Ridoux, V | 1 |
| Yu, PH | 1 |
| Ju, G | 1 |
| Hosford, DA | 1 |
| Wang, Y | 1 |
| Cao, Z | 1 |
| Deransart, C | 1 |
| Lê-Pham, BT | 1 |
| Hirsch, E | 1 |
| King, GA | 1 |
| Banerjee, PK | 1 |
| Hechler, V | 1 |
| Liu, Z | 1 |
12 other studies available for muscimol and Absence Seizure Disorder
| Article | Year |
|---|---|
Paroxysmal slow-wave discharges in a model of absence seizure are coupled to gamma oscillations in the thalamocortical and limbic systems.
Topics: Animals; Epilepsy, Absence; Hippocampus; Humans; Muscimol; Rats; Rats, Long-Evans; Seizures | 2023 |
The hippocampus participates in a pharmacological rat model of absence seizures.
Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Cortical Synchronization; Disease Models, Animal; Electro | 2016 |
Modifications of local cerebral glucose utilization in thalamic structures following injection of a dopaminergic agonist in the nucleus accumbens--involvement in antiepileptic effects?
Topics: Animals; Apomorphine; Autoradiography; Basal Ganglia; Deoxyglucose; Disease Models, Animal; Dopamine | 2004 |
Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy.
Topics: Action Potentials; Aminocaproates; Animals; Baclofen; Epilepsy, Absence; gamma-Aminobutyric Acid; Is | 1984 |
GABAA receptor function in the gamma-hydroxybutyrate model of generalized absence seizures.
Topics: Aminocaproates; Animals; Anticonvulsants; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicycl | 1993 |
Fos oncoprotein expression in the rat forebrain following muscimol-induced absence seizures.
Topics: Animals; Electroencephalography; Epilepsy, Absence; GABA Agonists; Immunohistochemistry; Male; Musci | 1996 |
Differential effects mediated by GABAA receptors in thalamic nuclei in lh/lh model of absence seizures.
Topics: Animals; Clonazepam; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Fe | 1997 |
Inhibition of the substantia nigra suppresses absences and clonic seizures in audiogenic rats, but not tonic seizures: evidence for seizure specificity of the nigral control.
Topics: Acoustic Stimulation; Animals; Auditory Pathways; Electroencephalography; Epilepsy, Absence; Epileps | 2001 |
Effects of systemically applied GABA agonists and antagonists on wave-spike ECoG activity in rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Electroencephalography; Epilepsy, Absence | 1979 |
The GABAA receptor complex in experimental absence seizures in rat: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; | 1992 |
Effect of intranigral muscimol on animal models of generalized absence seizures.
Topics: Animals; Convulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Epilepsy, G | 1992 |
Evidence for a critical role of GABAergic transmission within the thalamus in the genesis and control of absence seizures in the rat.
Topics: Aminocaproates; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, | 1991 |