muromonab-cd3 and Bronchial-Hyperreactivity

muromonab-cd3 has been researched along with Bronchial-Hyperreactivity* in 1 studies

Other Studies

1 other study(ies) available for muromonab-cd3 and Bronchial-Hyperreactivity

Article	Year
Effect of low level laser therapy on bronchial hyper-responsiveness. Lasers in medical science, 2009, Volume: 24, Issue:4 The objective of this study was to investigate whether low level laser therapy (LLLT) could reduce bronchial hyper-responsiveness (BHR) induced by tumour necrosis factor-alpha (TNF-alpha) modulating the metabolism of inositol phosphate (IP) in bronchial smooth muscle cells (BSMCs). The study was on 28 Wistar rats, randomly divided into four groups. Irradiation (1.3 J/cm(2)) was administered 5 min and 4 h after bronchial smooth muscle (BSM) had been suspended in TNF-alpha baths, and the contractile response-induced calcium ion (Ca(2+)) sensitization was measured. The BSMCs were isolated, and the IP accumulation was measured before and after TNF-alpha immersion in the groups that had been irradiated or not irradiated. BSM segments significantly increased contraction 24 h after TNF-alpha immersion when exposed to carbachol (CCh) as Ca(2+), but it was significantly reduced by 64% and 30%, respectively, after laser treatment. The increase in IP accumulation induced by CCh after TNF-alpha immersion was reduced in the BSMCs by LLLT. The dose of 2.6 J/cm(2) reduced BHR and IP accumulation in the rats' inflammatory BSMCs. Topics: Animals; Base Sequence; Bronchial Hyperreactivity; Calcium; Carbachol; DNA Primers; Gene Expression; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Low-Level Light Therapy; Macrocyclic Compounds; Male; Muscle Contraction; Myocytes, Smooth Muscle; Oxazoles; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha	2009

Article

Year

Effect of low level laser therapy on bronchial hyper-responsiveness.

Lasers in medical science, 2009, Volume: 24, Issue:4

The objective of this study was to investigate whether low level laser therapy (LLLT) could reduce bronchial hyper-responsiveness (BHR) induced by tumour necrosis factor-alpha (TNF-alpha) modulating the metabolism of inositol phosphate (IP) in bronchial smooth muscle cells (BSMCs). The study was on 28 Wistar rats, randomly divided into four groups. Irradiation (1.3 J/cm(2)) was administered 5 min and 4 h after bronchial smooth muscle (BSM) had been suspended in TNF-alpha baths, and the contractile response-induced calcium ion (Ca(2+)) sensitization was measured. The BSMCs were isolated, and the IP accumulation was measured before and after TNF-alpha immersion in the groups that had been irradiated or not irradiated. BSM segments significantly increased contraction 24 h after TNF-alpha immersion when exposed to carbachol (CCh) as Ca(2+), but it was significantly reduced by 64% and 30%, respectively, after laser treatment. The increase in IP accumulation induced by CCh after TNF-alpha immersion was reduced in the BSMCs by LLLT. The dose of 2.6 J/cm(2) reduced BHR and IP accumulation in the rats' inflammatory BSMCs.

Topics: Animals; Base Sequence; Bronchial Hyperreactivity; Calcium; Carbachol; DNA Primers; Gene Expression; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Low-Level Light Therapy; Macrocyclic Compounds; Male; Muscle Contraction; Myocytes, Smooth Muscle; Oxazoles; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha

2009