muraymycin-d2 and Bacterial-Infections

muraymycin-d2 has been researched along with Bacterial-Infections* in 1 studies

Other Studies

1 other study(ies) available for muraymycin-d2 and Bacterial-Infections

ArticleYear
Natural Products at Work: Structural Insights into Inhibition of the Bacterial Membrane Protein MraY.
    Angewandte Chemie (International ed. in English), 2016, 09-19, Volume: 55, Issue:39

    Natural(ly) fit: The X-ray crystal structure of the bacterial membrane protein MraY in complex with its natural product inhibitor muraymycin D2 is discussed. MraY catalyzes one of the membrane-associated steps in peptidoglycan biosynthesis and, therefore, represents a promising target for novel antibiotics. Structural insights derived from the protein-inhibitor complex might now pave the way for the development of new antimicrobial drugs.

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacterial Proteins; Biological Products; Crystallography, X-Ray; Humans; Molecular Docking Simulation; Nucleosides; Peptides; Peptidoglycan; Transferases; Transferases (Other Substituted Phosphate Groups)

2016