muramidase and Silicosis

muramidase has been researched along with Silicosis* in 7 studies

Other Studies

7 other study(ies) available for muramidase and Silicosis

ArticleYear
Serum lysozyme concentration in silicosis patients and workers exposed to silica dust.
    European journal of respiratory diseases, 1984, Volume: 65, Issue:7

    Lysozyme in serum (LZM, EC 3.2.1.17) was assayed in 135 male patients with silicosis. Twenty-eight of the patients had controls matched for exposure to silica dust, age and sex but with no radiographical signs of silicosis. A reference group without exposure to silica dust was composed of 34 lumberjacks. The mean concentration of serum LZM was higher in silicosis patients (7.8 +/- 2.8 mg/l, n = 28) than in the controls exposed to silica (6.0 +/- 1.7 mg/l, p less than 0.05), or in the lumberjacks (5.7 +/- 2.1 mg/l, p less than 0.01). There was an association between serum LZM concentration and radiographic severity of silicosis, and on a group basis an association of serum LZM concentration with the progression of silicosis. In the multivariate regression analysis the highest regression coefficients were found for progression of small opacities as well as patient age. The results suggest that the elevation of LZM concentration is associated with the progression of the disease.

    Topics: Adult; Age Factors; Aged; Humans; Male; Middle Aged; Muramidase; Radiography; Regression Analysis; Silicosis; Time Factors

1984
Angiotensin-converting enzyme. I. Activity and correlation with serum lysozyme in sarcoidosis, other chest or lymph node diseases and healthy persons.
    Scandinavian journal of respiratory diseases, 1979, Volume: 60, Issue:2

    Serum angiotensin-converting enzyme (ACE) activity was studied in healthy controls, in 57 untreated sarcoidosis patients, and in 164 patients with other chest or lymph node diseases. The serum ACE activity of healthy persons was independent of sex, intake of meals, and smoking habits. There were no diurnal variations. Healthy children had a significantly higher ACE mean value than adults, whose ACE activity was not affected by age. The sarcoidosis patients had the highest ACE mean values, but those of patients with silicosis and asbestosis were also significantly elevated. Pulmonary cancer patients had decreased serum ACE activity, which was probably due to antimitotic treatment. Serum lysozyme (LZM) concentrations did not correlate with normal ACE activity, but the correlation between elevated ACE and LZM was significant in sarcoidosis and silicosis, and the trend was clearly the same for asbestosis. This indicates separate sources for these enzymes when ACE activity is normal, and a common source, i.e. macrophages, when ACE activity is increased. ACE production in certain diseases involving macrophages may be due to the bradykinin inhibiting effect of this enzyme.

    Topics: Adolescent; Adult; Alveolitis, Extrinsic Allergic; Asbestosis; Bronchitis; Female; Hodgkin Disease; Humans; Lung Diseases; Lung Neoplasms; Lymphatic Diseases; Lymphoma; Male; Middle Aged; Muramidase; Peptidyl-Dipeptidase A; Pneumonia; Pulmonary Fibrosis; Sarcoidosis; Silicosis; Thoracic Neoplasms; Tuberculosis, Lymph Node; Tuberculosis, Pulmonary

1979
Angiotensin-converting enzyme and lysozyme in silicosis and asbestosis.
    Scandinavian journal of respiratory diseases, 1978, Volume: 59, Issue:4

    Serum angiotensin-converting enzyme (ACE) activity and lysozyme (LZM) concentration in 22 silicosis and 18 asbestosis patients were studied. These patients were compared with 57 untreated and 36 treated sarcoidosis patients. In all groups significantly raised ACE and LZM mean values were noted. Untreated sarcoidosis patients had the highest values. Raised ACE activity in silicosis and asbestosis has not been reported before, and weakens the differential diagnostic value of this enzyme determination for sarcoidosis. The similar patterns of increased ACE and LZM mean values in all three diseases suggest that these enzymes have a common source.

    Topics: Adult; Aged; Asbestosis; Diagnosis, Differential; Female; Humans; Lung Diseases; Male; Middle Aged; Muramidase; Peptidyl-Dipeptidase A; Sarcoidosis; Silicosis

1978
[Changes in the percentual quota of lymphocytes in silicotics after intravenous treatment with ascorbic acid and lysozyme].
    Folia medica. Folia medica (Naples, Italy), 1968, Volume: 51, Issue:11

    Topics: Adult; Aged; Ascorbic Acid; Humans; Injections, Intravenous; Lymphocytes; Male; Middle Aged; Muramidase; Silicosis

1968
[On some pathogenic aspects of silicosis. Agglutination by lysozyme of micronic particles of quartz suspended in blood serum].
    Bollettino della Societa italiana di biologia sperimentale, 1961, Apr-30, Volume: 37

    Topics: Anti-Infective Agents, Local; Antiviral Agents; Hemagglutination; Hemagglutination Tests; Humans; Muramidase; Quartz; Serum; Silicosis

1961
[Lysozyme activity in the blood serum of 200 silicotics].
    La Medicina del lavoro, 1961, Volume: 52

    Topics: Humans; Muramidase; Serum; Silicosis

1961
[Research on lysozymic power and cholesterolemia in silicotics].
    Folia medica. Folia medica (Naples, Italy), 1955, Volume: 38, Issue:6

    Topics: Anti-Infective Agents, Local; Antiviral Agents; Blood; Cholesterol; Dermatologic Agents; Muramidase; Silicosis

1955