muramidase and Neurilemmoma

An immunohistochemical technique for the detection of S-100 protein, neuron specific enolase (NSE), carcinoembryonic antigen (CEA) and muramidase (lysozyme) was applied to a case of the granular cell tumour. S-100 protein was detected both in the nuclei and cytoplasma of the granular cells, and NSE was weakly positive in their cytoplasms. CEA and lysozyme were negative in the tumour cells. Our results supports the concept that granular cell tumours are derived from Schwann cells.

Topics: Adult; Carcinoembryonic Antigen; Female; Humans; Immunohistochemistry; Muramidase; Neoplasms, Muscle Tissue; Neurilemmoma; Phosphopyruvate Hydratase; S100 Proteins; Skin Neoplasms

The presence of lysozyme in the CSF is considered with regard to its value in the early diagnosis of primary or secondary CNS Tumours. Since the appearance of this enzyme in the CSF is secondary to the increase of protein in the fluid, the search for lysozyme in the CSF is of no practical help in the diagnosis of CNS tumours.

Topics: Adolescent; Adult; Aged; Brain Neoplasms; Central Nervous System Diseases; Cerebral Ventricles; Child; Child, Preschool; Craniopharyngioma; Cysts; Female; Glioma; Humans; Hydrocephalus; Infant; Male; Meningioma; Meningitis; Middle Aged; Muramidase; Neoplasm Metastasis; Neurilemmoma; Neuroblastoma; Peripheral Nervous System Neoplasms; Time Factors; Vestibulocochlear Nerve

Topics: Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid; Craniopharyngioma; Glioma; Humans; Meningioma; Muramidase; Neurilemmoma; Neuroblastoma; Vestibulocochlear Nerve