muramidase and Headache

Granulocytic sarcoma is a form of extramedullary leukaemia. The intraparenchymal localisation is extremely rare. We report a case of cerebellar granulocytic sarcoma occuring in a 43 years old woman without any precedent medical history. The diagnosis of granulocytic sarcoma was established by neoplastic cells findings through morphological and immunohistochemical studies. The patient died few days after surgery. There are still no conclusive treatment strategies for this entity; however, early antileukemic chemotherapy seems to lower the probability of developing systemic disease and thus prolong survival.

Topics: Adult; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers, Tumor; Carboxylic Ester Hydrolases; Cerebellar Neoplasms; Fatal Outcome; Female; Headache; Hepatomegaly; Humans; Immunoenzyme Techniques; Muramidase; Neoplasm Proteins; Peroxidase; Sarcoma, Myeloid; Splenomegaly; Staining and Labeling