muramidase and Fibrocystic-Breast-Disease

muramidase has been researched along with Fibrocystic-Breast-Disease* in 2 studies

Other Studies

2 other study(ies) available for muramidase and Fibrocystic-Breast-Disease

ArticleYear
Altered monocyte function in patients with benign breast disease.
    Clinical and experimental immunology, 1987, Volume: 67, Issue:1

    Monocyte migration, lysozyme production and phagocytosis was studied in 34 patients with fibroadenosis, 28 patients with fibroadenoma and 48 healthy female controls. In patients with fibroadenosis and fibroadenoma, monocyte migration and phagocytic activity were significantly reduced when compared to controls (P less than 0.001). Conversely, lysozyme production by monocytes from patients with benign breast disease was significantly higher than in controls (P less than 0.001). In 20 patients with benign breast disease, there was no significant difference in monocyte function before and 3 months after operation. The observed impairment of monocyte function in fibroadenosis and fibroadenoma would not appear to be the result of abnormal blood biochemistry or due to a direct serum inhibitor, but is probably related to an intrinsic cellular defect. Further studies are required to evaluate the significance of impaired monocyte function in the pathophysiology of benign breast disease.

    Topics: Adenofibroma; Adolescent; Adult; Breast Diseases; Breast Neoplasms; Chemotaxis, Leukocyte; Female; Fibrocystic Breast Disease; Humans; Middle Aged; Monocytes; Muramidase; Phagocytosis

1987
Protein concentrations in fluid from gross cystic disease of the breast.
    Clinical oncology, 1984, Volume: 10, Issue:1

    Wide variations in the concentrations of IgA, IgG, lactoferrin, lysozyme and albumin were found in 96 cyst fluids obtained from 75 patients with gross cystic disease of the breast. Sedimentation coefficient determination were performed on 19 of the cyst fluids with the highest IgA concentrations in an attempt to discover the basis for the wide variation and two types of cyst fluids were found: cyst fluids that resembled external secretions such as colostrum of milk with the IgA wholly or predominantly in the 11S (secretory) form, and low concentrations of IgG and albumin, and cyst fluids that resembled serum with the IgA wholly or predominantly in the 7S (serum) form, and high concentrations of IgG and albumin. Some cyst fluids contained low concentrations of all proteins measured, and no relationship was observed between the concentrations of the proteins studied, and age, parity or menstrual status.

    Topics: Adult; Albumins; Exudates and Transudates; Female; Fibrocystic Breast Disease; Humans; Immunoglobulin A; Immunoglobulin G; Lactoferrin; Middle Aged; Molecular Weight; Muramidase; Proteins

1984