muramidase and Corneal-Ulcer

Topics: Corneal Ulcer; Eye Infections; Humans; Immunodiffusion; Immunoglobulins; Muramidase; Tears

Low levels of tear lysozyme were observed in patients with infective corneal ulcers, when compared with controls. Lowest levels were seen in patients with bacterial corneal ulcers. The levels of tear lysozyme showed a corresponding decrease with the increase in Schirmer test values; meaning thereby, that in ocular conditions associated with increased rate of tear flow, the lysozyme content in tears tends to be low.

Topics: Adult; Corneal Ulcer; Eye Infections; Eye Infections, Bacterial; Eye Infections, Fungal; Eye Infections, Viral; Female; Humans; Male; Middle Aged; Muramidase; Tears

Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Conjunctivitis; Corneal Ulcer; Humans; Infant; Keratitis, Dendritic; Middle Aged; Muramidase; Secretory Rate; Tears

In the present experimental study the role of lysozyme drops in healing of corneal ulcer of staphylococcal origin (sensitive to chloramphenicol) was studied on 16 albino rabbits. In 8 rabbits, in one eye placibo drops (distilled water) and in the other eye lysozyme 1% were put 4 times daily. In the other 8 rabbits, in one eye chloramphenicol drops 0.4% and in the other eye chloramphenicol drops 0.4% + lysozyme drops 1% were instilled 4 times daily. It was observed that the rate of healing of corneal ulcer was much earlier in the eyes which had local instillation of chloramphenicol drops + lysozyme in comparison to the eyes which had only chloramphenicol drops, lysozyme drops, or distilled water.

Topics: Animals; Chloramphenicol; Corneal Ulcer; Muramidase; Ophthalmic Solutions; Rabbits; Remission, Spontaneous

Topics: Conjunctivitis; Corneal Ulcer; Eye Diseases; Humans; Hypersensitivity; Keratoconjunctivitis; Muramidase; Tears

Topics: Animal Experimentation; Animals; Anti-Infective Agents, Local; Antiviral Agents; Cornea; Corneal Ulcer; Dexamethasone; Lagomorpha; Muramidase; Pharmacology; Rabbits; Research; Ulcer