muramidase has been researched along with Colonic-Diseases--Functional* in 2 studies
2 other study(ies) available for muramidase and Colonic-Diseases--Functional
| Article | Year |
|---|---|
Clinical relevance of lysozyme in the faeces.
To elucidate the value of faecal lysozyme determination in the differential diagnosis of patients with atypical abdominal complaints, stool samples of healthy controls, patients with irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) were analysed. Faecal lysozyme concentration in healthy controls ranged from 0 to 6 mg/l with a mean of 3 mg/l. Patients with IBS had similar faecal lysozyme levels. In contrast, faecal lysozyme concentrations in patients with IBD were increased (range 6 to 104 mg/l). The difference between patients with IBS and IBD was highly significant (P less than 0.001). The determination of faecal lysozyme concentration may provide a useful test in the work-up of patients with abdominal complaints. In addition, the faeces lysozyme concentration appeared to be an objective parameter of the inflammatory activity of IBD in 11 patients investigated. Topics: Colitis, Ulcerative; Colonic Diseases, Functional; Crohn Disease; Diagnosis, Differential; Feces; Humans; Inflammatory Bowel Diseases; Muramidase | 1989 |
Faecal lysozyme: determination, reference intervals and some data in gastro-intestinal disease.
After diluting faecal samples with a solution of Brij and saline and subsequently ultrafiltrating the faecal mixtures, lysozyme concentration can be reproducibly measured in the obtained faecal fluids, using a turbidimetric method. Measuring faecal lysozyme concentration enables discrimination normal individuals and patients with irritable bowel syndrome between patients with inflammatory bowel disease and colonic cancer. Lysozyme distribution in stools appears to be homogeneous. Faecal lysozyme concentration is stable when samples are stored during at least 1 wk at 6 degrees C. It appears that the lysozyme activity is directly correlated with the clinical status and severity of the disease. Faecal lysozyme may thus serve as an important tool both in diagnosis and in follow-up in the out-patients clinic for gastroenterology. Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colonic Diseases, Functional; Colonic Neoplasms; Feces; Gastrointestinal Diseases; Humans; Immunodiffusion; Middle Aged; Muramidase; Nephelometry and Turbidimetry; Reference Standards | 1987 |