mupirocin and Maxillary-Sinusitis

The study assessed efficiency of local antibiotic therapy with mupirocin and amoxicillin/clavulanate in 28 patients radically operated on the maxillary sinus (MS). Early after the operation, MS tamponing with a latex tampon was made. The tampon was filled with mupirocin for patients of group 1. In patients of group 2 and controls the tampon was sterile but in group 2 after the tampon removal postoperative maxillary washing was made with amoxicillin/clavulanate solution. The results of the study demonstrated high efficiency of local administration of mupirocin and amoxicillin/clavulanate and validity of bacteriological examination in planning antibiotic therapy early after surgery.

Topics: Amoxicillin-Potassium Clavulanate Combination; Drug Therapy, Combination; Female; Humans; Male; Maxillary Sinus; Maxillary Sinusitis; Mupirocin; Treatment Outcome