moxonidine has been researched along with Heart Disease, Ischemic in 5 studies
moxonidine: structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moxonidine was well tolerated in this single-dose study and resulted in a modest, dose-dependent, vasodilator response, with substantial reductions in systemic and pulmonary arterial blood pressure." | 6.69 | Acute hemodynamic and neurohumoral effects of moxonidine in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. ( Aarsland, T; Dickstein, K; Køpp, U; Manhenke, C; McNay, J; Wiltse, C, 1999) |
| "Moxonidine was well tolerated in this single-dose study and resulted in a modest, dose-dependent, vasodilator response, with substantial reductions in systemic and pulmonary arterial blood pressure." | 2.69 | Acute hemodynamic and neurohumoral effects of moxonidine in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. ( Aarsland, T; Dickstein, K; Køpp, U; Manhenke, C; McNay, J; Wiltse, C, 1999) |
| "Moxonidine has been shown to be antiarrhythmic during ischaemia in vivo." | 1.30 | Facilitation of spontaneous defibrillation by moxonidine during regional ischaemia in an isolated working rabbit heart model. ( Cobbe, SM; Hicks, MN; Kane, KA; Wolk, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Kerckhoven, R | 1 |
| Saxena, PR | 1 |
| Schoemaker, RG | 1 |
| Dikow, R | 1 |
| Kihm, LP | 1 |
| Zeier, M | 1 |
| Kapitza, J | 1 |
| Törnig, J | 1 |
| Amann, K | 1 |
| Tiefenbacher, C | 1 |
| Ritz, E | 1 |
| Bolliger, D | 1 |
| Seeberger, MD | 1 |
| Lurati Buse, GA | 1 |
| Christen, P | 1 |
| Gürke, L | 1 |
| Filipovic, M | 1 |
| Wolk, R | 1 |
| Kane, KA | 1 |
| Cobbe, SM | 1 |
| Hicks, MN | 1 |
| Dickstein, K | 1 |
| Manhenke, C | 1 |
| Aarsland, T | 1 |
| Køpp, U | 1 |
| McNay, J | 1 |
| Wiltse, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Small Doses of Moxonidine in Patients Undergoing Vascular Surgery[NCT00244504] | Phase 3 | 141 participants (Actual) | Interventional | 2002-11-30 | Terminated (stopped due to Study was stopped after pre-definied interim analysis because of no effects) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for moxonidine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Randomized clinical trial of moxonidine in patients undergoing major vascular surgery.
Topics: Aged; Coronary Artery Disease; Double-Blind Method; Female; Hemodynamics; Hospitalization; Humans; I | 2007 |
Acute hemodynamic and neurohumoral effects of moxonidine in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
Topics: Administration, Oral; Aged; Analysis of Variance; Antihypertensive Agents; Cardiomyopathy, Dilated; | 1999 |
3 other studies available for moxonidine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Restored capillary density in spared myocardium of infarcted rats improves ischemic tolerance.
Topics: Animals; Capillaries; Imidazoles; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Ische | 2002 |
Increased infarct size in uremic rats: reduced ischemia tolerance?
Topics: Animals; Body Weight; Coronary Vessels; Heart Ventricles; Hydralazine; Imidazoles; Ischemia; Male; M | 2004 |
Facilitation of spontaneous defibrillation by moxonidine during regional ischaemia in an isolated working rabbit heart model.
Topics: Action Potentials; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Disease Models, Animal; E | 1999 |