Page last updated: 2024-11-02

moxonidine and Bradycardia

moxonidine has been researched along with Bradycardia in 3 studies

moxonidine: structure given in first source

Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Research Excerpts

ExcerptRelevanceReference
"In the present study, we investigated the effects of pretreatment with NG-nitro-L-arginine methyl ester (L-NAME) (nitric oxide synthase inhibitor) injected intravenously (IV) on the hypotension, bradycardia, and vasodilation produced by moxonidine (alpha2-adrenergic/imidazoline receptor agonist) injected into the fourth brain ventricle (4th V) in rats submitted to acute hypertension that results from baroreflex blockade by bilateral injections of kynurenic acid (kyn, glutamatergic receptor antagonist) into the nucleus of the solitary tract (NTS) or in normotensive rats."3.73Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide. ( Colombari, E; Menani, JV; Moreira, TS; Sato, MA; Takakura, AC, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moreira, TS2
Takakura, AC2
Menani, JV2
Sato, MA2
Colombari, E2
Chan, CK1
Burke, SL1
Zhu, H1
Piletz, JE1
Head, GA1

Other Studies

3 other studies available for moxonidine and Bradycardia

ArticleYear
Central blockade of nitric oxide synthesis reduces moxonidine-induced hypotension.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: Animals; Bradycardia; Brain Stem; Brazil; Drug Combinations; Echocardiography, Doppler, Pulsed; Four

2004
Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine.
    Neuroscience, 2005, Volume: 132, Issue:4

    Topics: 5,6-Dihydroxytryptamine; Adrenergic Agents; Animals; Antihypertensive Agents; Blotting, Western; Bra

2005
Antihypertensive responses elicited by central moxonidine in rats: possible role of nitric oxide.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:6

    Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradycardia; Drug Interactions; Endoth

2006