moxisylyte has been researched along with Muscle Contraction in 21 studies
Moxisylyte: An alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dose-response curves were parallel and no statistically significant difference could be shown between the IC50 values." | 1.29 | Adrenergic receptors on smooth muscle cells isolated from human penile corpus cavernosum. ( Bali, JP; Costa, P; Navratil, H; Rebillard, X; Sarrazin, B; Soulie-Vassal, ML, 1993) |
| "Moxisylyte has a relaxant action on the urethra that is probably ascribable to its alpha 1-adrenoceptor antagonist and Ca++ antagonist actions." | 1.28 | [Effect of moxisylyte on the lower urinary tracts (1). Effect on the isolated rabbit urethra and bladder]. ( Hayashi, Y; Ikeda, K; Ohnishi, H; Watanabe, K, 1991) |
| "Moxisylyte hydrochloride is an agent with potential clinical and research uses capable of producing erection when injected intra-cavernously." | 1.28 | Effect of moxisylyte hydrochloride on isolated human penile corpus cavernosum tissue. ( Imagawa, A; Kawanishi, Y; Kimura, K; Tamura, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (76.19) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lograno, MD | 1 |
| Daniele, E | 1 |
| Conte-Camerino, D | 1 |
| Creuzet, MH | 1 |
| Prat, G | 1 |
| Malek, A | 2 |
| Fauran, F | 1 |
| Roquebert, J | 2 |
| Demichel, P | 1 |
| Malo, PE | 1 |
| Wasserman, MA | 1 |
| Onnen, I | 1 |
| Isambert, JL | 1 |
| Egon, G | 1 |
| Colombel, P | 1 |
| Costa, P | 1 |
| Soulie-Vassal, ML | 1 |
| Sarrazin, B | 1 |
| Rebillard, X | 1 |
| Navratil, H | 1 |
| Bali, JP | 1 |
| de Tejada, IS | 1 |
| Garvey, DS | 1 |
| Schroeder, JD | 1 |
| Shelekhin, T | 1 |
| Letts, LG | 1 |
| Fernández, A | 1 |
| Cuevas, B | 1 |
| Gabancho, S | 1 |
| Martínez, V | 1 |
| Angulo, J | 1 |
| Trocha, M | 1 |
| Marek, P | 1 |
| Cuevas, P | 1 |
| Tam, SW | 1 |
| Kamburoff, PL | 1 |
| Kapur, H | 1 |
| Mottram, DR | 1 |
| Anstey, MD | 1 |
| Birmingham, AT | 1 |
| Watanabe, K | 2 |
| Hayashi, Y | 2 |
| Ikeda, K | 2 |
| Ohnishi, H | 2 |
| Imagawa, A | 1 |
| Kimura, K | 1 |
| Kawanishi, Y | 1 |
| Tamura, M | 1 |
| Anderson, RJ | 1 |
| Marcelle, R | 1 |
| Laurent, B | 1 |
| Arbab, AG | 1 |
| Turner, P | 1 |
| Variava, DM | 1 |
| Collis, MG | 1 |
| Alps, BJ | 1 |
| Fawke, L | 1 |
| Müller-Schweinitzer, E | 1 |
| Stürmer, E | 1 |
| Phillips, SJ | 1 |
| Richens, A | 1 |
| Shand, DG | 1 |
1 review available for moxisylyte and Muscle Contraction
| Article | Year |
|---|---|
Bronchomotor tone and its modification by certain drugs.
Topics: Airway Resistance; Albuterol; Bronchi; Histamine H1 Antagonists; Humans; Indoramin; Isoproterenol; M | 1976 |
20 other studies available for moxisylyte and Muscle Contraction
| Article | Year |
|---|---|
The effect of thymoxamine on guinea-pig ileum contractions.
Topics: Animals; Calcium; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Guinea Pigs; | 1984 |
In vitro and in vivo alpha-blocking activity of thymoxamine and its two metabolites.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dealkylation; Dogs; Female; In Vitro Techniqu | 1980 |
Antinoradrenergic activity of thymoxamine and its metabolites in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Biotransformation; In Vitro Techniques; Male | 1981 |
The modulation of adrenergic airway tone in normal and ascaris-sensitive beagle dogs.
Topics: Adrenergic alpha-Agonists; Animals; Ascaris; Dinoprost; Dogs; Female; Hypersensitivity; In Vitro Tec | 1982 |
Non-specific, time-dependent desensitization of the vas deferens and anococcygeus preparations of the rat to alpha 1-adrenoceptor antagonists and atropine.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; In Vitro Techniques; Kinetics; Male; Mox | 1984 |
Adjuvant drug therapy: a review of 30 cases of sacral anterior root stimulator.
Topics: Chemotherapy, Adjuvant; Electric Stimulation Therapy; Female; Humans; Male; Moxisylyte; Muscle Contr | 1993 |
Adrenergic receptors on smooth muscle cells isolated from human penile corpus cavernosum.
Topics: Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Moxisylyte; Muscle Contraction; | 1993 |
Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence.
Topics: Adrenergic alpha-Antagonists; Animals; Cyclic GMP; Drug Design; Endothelins; Erectile Dysfunction; H | 1999 |
The interaction of WB4101, and other alpha-adrenoceptor antagonists, on 5-hydroxytryptamine receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Dioxanes; Dioxins; In Vitro Techniques; Male | 1979 |
The response of the circular muscle layer of the guinea-pig isolated vas deferens to transmural electrical stimulation.
Topics: Anesthetics, Local; Animals; Bethanidine; Electric Stimulation; Guanethidine; Guinea Pigs; In Vitro | 1978 |
[Effect of moxisylyte on the lower urinary tracts (1). Effect on the isolated rabbit urethra and bladder].
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; I | 1991 |
[Effect of moxisylyte on the lower urinary tracts (2). Effect on the urethra in anesthetized dogs].
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Femal | 1991 |
Effect of moxisylyte hydrochloride on isolated human penile corpus cavernosum tissue.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; In Vitro Te | 1989 |
Modification of reserpine induced rigidity by dopaminergic and alpha-adrenergic drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Dopamine; Male; Moxisylyte; Muscle Contraction; Muscle Tonus; | 1985 |
[Reactivity of human bronchi in vitro].
Topics: Acetylcholine; Airway Resistance; Atropine; Bradykinin; Bronchi; Cromolyn Sodium; Histamine; Histami | 1973 |
The -adrenoceptor blocking activity of desacetylthymoxamine on human isolated smooth muscle.
Topics: Adrenergic alpha-Antagonists; Colon; Dose-Response Relationship, Drug; Humans; Ileum; In Vitro Techn | 1973 |
The evaluation of the alpha-adrenoceptor blocking action of indoramin, phentolamine and thymoxamine on the rat and guinea-pig isolated mesenteric vasculature and aortic spiral preparations.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Benzamides; Blood Vessels; In Vitro Techniques; Indole | 1973 |
Proceedings: Is thymoxamine a specific alpha-adrenoceptor blocking agent?
Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Guinea Pigs; Hypogastric Plexus; In Vit | 1972 |
Investigations on the mode of action of ergotamine in the isolated femoral vein of the dog.
Topics: Adrenergic alpha-Antagonists; Animals; Dibenzylchlorethamine; Dogs; Dose-Response Relationship, Drug | 1974 |
Adrenergic control of tendon jerk reflexes in man.
Topics: Blood Pressure; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Humans; Methamphetam | 1973 |