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moxisylyte and Impotence

moxisylyte has been researched along with Impotence in 19 studies

Moxisylyte: An alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)

Research Excerpts

ExcerptRelevanceReference
"We compared the efficacy and safety of alprostadil alpha-cyclodextrin and moxisylyte chlorhydrate to induce erections adequate for sexual intercourse in a prospective, randomized, parallel double-blind study in patients with erectile dysfunction."9.08Double-blind multicenter study comparing alprostadil alpha-cyclodextrin with moxisylyte chlorhydrate in patients with chronic erectile dysfunction. ( Albrecht, D; Buvat, J; Costa, P; Lecocq, B; Morlier, D; Stegmann, B, 1998)
"Moxisylyte is a competitive noradrenaline antagonist, acting preferentially on post-synaptic alpha-1 adrenoceptors."6.40Moxisylyte: a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in impotence. ( Bressolle, F; Marquer, C, 1998)
"Moxisylyte chlorhydrate is a selective alpha-blocker of the post-synaptic alpha 1-adrenoreceptors."5.29[Prolonged use of moxisylyte chlorhydrate (Icavex) by intracavernous self-injections in the treatment of impotence. Evaluation of long-term tolerance]. ( Arvis, G; Rivet, G; Schwent, B, 1996)
"We compared the efficacy and safety of alprostadil alpha-cyclodextrin and moxisylyte chlorhydrate to induce erections adequate for sexual intercourse in a prospective, randomized, parallel double-blind study in patients with erectile dysfunction."5.08Double-blind multicenter study comparing alprostadil alpha-cyclodextrin with moxisylyte chlorhydrate in patients with chronic erectile dysfunction. ( Albrecht, D; Buvat, J; Costa, P; Lecocq, B; Morlier, D; Stegmann, B, 1998)
"We assessed the efficiency and tolerance of the alpha-blocking agent moxisylyte in 2 double-blind studies versus placebo performed in 12 neurogenic patients with spinal cord lesions and in 61 patients presenting with either psychogenic impotence (30) or erectile dysfunction that was predominantly neither psychogenic, hormonal nor neurogenic (31)."5.07Efficiency and side effects of intracavernous injections of moxisylyte in impotent patients: a dose-finding study versus placebo. ( Bondil, P; Bressolle, F; Colson, MH; Costa, P; Sarrazin, B; Saudubray, F, 1993)
"We tested the possibility of using intracavernous injections of the alpha-blocking agent moxisylyte (6-acetoxy-thymoxy-ethyl-dimethylamine) as treatment of erectile impotence."5.06Safety of intracavernous injections using an alpha-blocking agent. ( Buvat, J; Buvat-Herbaut, M; Lemaire, A; Marcolin, G, 1989)
" The literature search was restricted to articles published in English, French, and Spanish up to November 2014 using the key words alprostadil, papaverine, moxisylite, alpha-blocking agent, phentolamine, intracavernous injection, spinal cord injuries, paraplegia, quadriplegia, and erectile dysfunction."4.93Intracavernous Injections in Spinal Cord Injured Men With Erectile Dysfunction, a Systematic Review and Meta-Analysis. ( Bonan, I; Chéhensse, C; Chochina, L; Damphousse, M; Giuliano, F; Manunta, A; Naudet, F, 2016)
"Alprostadil was used 51 times, moxisylite nine times and papaverine four times."2.70[Intracavernous injections in the treatment of erectile dysfunction in spinal cord injured patients: experience with 36 patients]. ( Boiteau, F; Boyer, F; Dizien, O; Laffont, I; Lebib Ben Achour, S, 2001)
"Moxisylyte is a competitive noradrenaline antagonist, acting preferentially on post-synaptic alpha-1 adrenoceptors."2.40Moxisylyte: a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in impotence. ( Bressolle, F; Marquer, C, 1998)
"Moxisylyte chlorhydrate is a selective alpha-blocker of the post-synaptic alpha 1-adrenoreceptors."1.29[Prolonged use of moxisylyte chlorhydrate (Icavex) by intracavernous self-injections in the treatment of impotence. Evaluation of long-term tolerance]. ( Arvis, G; Rivet, G; Schwent, B, 1996)
"Moxisylyte hydrochloride is an agent with potential clinical and research uses capable of producing erection when injected intra-cavernously."1.28Effect of moxisylyte hydrochloride on isolated human penile corpus cavernosum tissue. ( Imagawa, A; Kawanishi, Y; Kimura, K; Tamura, M, 1989)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's13 (68.42)18.2507
2000's1 (5.26)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chochina, L1
Naudet, F1
Chéhensse, C1
Manunta, A1
Damphousse, M1
Bonan, I1
Giuliano, F1
Porst, H1
Buvat, J4
Buvat-Herbaut, M2
Lemaire, A3
Marcolin, G2
Costa, P5
Sarrazin, B2
Bressolle, F3
Mottet, N1
Louis, JF2
Saudubray, F2
Navratil, H2
Colson, MH1
Bondil, P2
Andro, MC2
Saur, P1
Hermabessiere, J1
Herbaut-Buvat, M1
Arvis, G1
Rivet, G1
Schwent, B1
Morlier, D1
Lecocq, B1
Stegmann, B1
Albrecht, D1
Gingell, JC1
Marquer, C1
de Tejada, IS1
Garvey, DS1
Schroeder, JD1
Shelekhin, T1
Letts, LG1
Fernández, A1
Cuevas, B1
Gabancho, S1
Martínez, V1
Angulo, J1
Trocha, M1
Marek, P1
Cuevas, P1
Tam, SW1
Lebib Ben Achour, S1
Laffont, I1
Boyer, F1
Boiteau, F1
Dizien, O1
Imagawa, A1
Kimura, K1
Kawanishi, Y1
Tamura, M1
Schouman, M1
Amer, M1
Jardin, A1
Bensadoun, H1
Benoit, G1
Puech, A1
Alexandre, L1

Reviews

3 reviews available for moxisylyte and Impotence

ArticleYear
Intracavernous Injections in Spinal Cord Injured Men With Erectile Dysfunction, a Systematic Review and Meta-Analysis.
    Sexual medicine reviews, 2016, Volume: 4, Issue:3

    Topics: Alprostadil; Erectile Dysfunction; Humans; Male; Moxisylyte; Papaverine; Penile Erection; Prospectiv

2016
New developments in self-injection therapy for erectile dysfunction.
    British journal of urology, 1998, Volume: 81, Issue:4

    Topics: Alprostadil; Calcitonin Gene-Related Peptide; Chlorpromazine; Dose-Response Relationship, Drug; Erec

1998
Moxisylyte: a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in impotence.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:4

    Topics: Absorption; Animals; Drug Administration Routes; Erectile Dysfunction; Humans; Male; Moxisylyte; Ran

1998

Trials

7 trials available for moxisylyte and Impotence

ArticleYear
[Treatment of impotence with intracavernous auto-injections: moxisylyte diminishes the risks compared to papaverine].
    Contraception, fertilite, sexualite (1992), 1993, Volume: 21, Issue:2

    Topics: Adult; Aged; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Moxisylyte; Papaverine; Pe

1993
Efficiency and side effects of intracavernous injections of moxisylyte in impotent patients: a dose-finding study versus placebo.
    The Journal of urology, 1993, Volume: 149, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Erectile Dysfunction; Humans; Male; Mi

1993
[Effectiveness of and tolerance to intracavernous injection of moxisylyte in patients with erectile dysfunction: effect/dose relationship versus placebo].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1995, Volume: 5, Issue:5

    Topics: Adult; Aged; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Erectile Dys

1995
[Efficacy and tolerance of intracavernous injection of moxisylyte in patients with erectile dysfunction: double-blind placebo-controlled study].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1995, Volume: 5, Issue:6

    Topics: Adult; Aged; Double-Blind Method; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Moxis

1995
Double-blind multicenter study comparing alprostadil alpha-cyclodextrin with moxisylyte chlorhydrate in patients with chronic erectile dysfunction.
    The Journal of urology, 1998, Volume: 159, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; alpha-Cyclodextrins; Alprostadil; Chronic Disease; Cyclod

1998
[Intracavernous injections in the treatment of erectile dysfunction in spinal cord injured patients: experience with 36 patients].
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2001, Volume: 44, Issue:1

    Topics: Adult; Alprostadil; Erectile Dysfunction; Humans; Male; Moxisylyte; Papaverine; Patient Satisfaction

2001
Safety of intracavernous injections using an alpha-blocking agent.
    The Journal of urology, 1989, Volume: 141, Issue:6

    Topics: Adult; Double-Blind Method; Erectile Dysfunction; Humans; Male; Middle Aged; Moxisylyte; Papaverine;

1989

Other Studies

9 other studies available for moxisylyte and Impotence

ArticleYear
The rationale for prostaglandin E1 (alpha-alprostadil) in the management of male impotence.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Alprostadil; Erectile Dysfunction; Humans; Impotence, Vasculogenic; Male; Molsidomine; Moxisylyte; P

1995
Is the volume injected a parameter likely to influence the erectile response observed after intracavernous administration of an alpha-blocking agent?
    European urology, 1993, Volume: 24, Issue:1

    Topics: Adult; Erectile Dysfunction; Humans; Injections; Male; Moxisylyte; Penile Erection; Solutions; Solve

1993
[Treatment of erectile insufficiency].
    Presse medicale (Paris, France : 1983), 1995, Oct-28, Volume: 24, Issue:32

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Alprostadil; Erectile Dysfunction; Humans

1995
Intracavernous pharmacotherapy: comparison of Moxisylyte and prostaglandin E1.
    International journal of impotence research, 1996, Volume: 8, Issue:2

    Topics: Adult; Aged; Alprostadil; Dose-Response Relationship, Drug; Erectile Dysfunction; Fibrosis; Humans;

1996
[Prolonged use of moxisylyte chlorhydrate (Icavex) by intracavernous self-injections in the treatment of impotence. Evaluation of long-term tolerance].
    Journal d'urologie, 1996, Volume: 102, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Erectile Dysfunction; Follow-Up Studies; Humans; Male; Mi

1996
Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Cyclic GMP; Drug Design; Endothelins; Erectile Dysfunction; H

1999
Effect of moxisylyte hydrochloride on isolated human penile corpus cavernosum tissue.
    Life sciences, 1989, Volume: 44, Issue:9

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; In Vitro Te

1989
[Value of the visual stimulation test (VST) as initial paraclinical test in the study of erectile impotence. Classification of psychogenic impotence using computerized rigidimetry. The value of thymoxamine].
    Acta urologica Belgica, 1989, Volume: 57, Issue:1

    Topics: Adult; Aged; Erectile Dysfunction; Humans; Male; Middle Aged; Moxisylyte; Papaverine; Penile Erectio

1989
[What can be expected of intracavernous injections?].
    Acta urologica Belgica, 1988, Volume: 56, Issue:2

    Topics: Adult; Aged; Apomorphine; Erectile Dysfunction; Humans; Injections; Injections, Subcutaneous; Male;

1988