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moxisylyte and Asthma

moxisylyte has been researched along with Asthma in 19 studies

Moxisylyte: An alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"In six patients with extrinsic bronchial asthma the inhalation of prostaglandin (PG) F2 alpha in a small dosage produced significant bronchoconstriction, whereas PGE2 produced bronchodilatation."6.64Atropine, sodium cromoglycate, and thymoxamine in PGF2 alpha-induced bronchoconstriction in extrinsic asthma. ( Patel, KR, 1975)
"Of the 22 patients with extrinsic bronchial asthma, 13 patients developed post-exercise bronchoconstriction after treadmill exercise, whereas in 9 patients treadmill exercise had no effect on the ventilatory capacity."6.64The effect of thymoxamine and cromolyn sodium on postexercise bronchoconstriction in asthma. ( Kerr, JW; MacDonald, EB; MacKenzie, AM; Patel, KR, 1976)
"In six patients with extrinsic bronchial asthma the inhalation of prostaglandin (PG) F2 alpha in a small dosage produced significant bronchoconstriction, whereas PGE2 produced bronchodilatation."2.64Atropine, sodium cromoglycate, and thymoxamine in PGF2 alpha-induced bronchoconstriction in extrinsic asthma. ( Patel, KR, 1975)
"Of the 22 patients with extrinsic bronchial asthma, 13 patients developed post-exercise bronchoconstriction after treadmill exercise, whereas in 9 patients treadmill exercise had no effect on the ventilatory capacity."2.64The effect of thymoxamine and cromolyn sodium on postexercise bronchoconstriction in asthma. ( Kerr, JW; MacDonald, EB; MacKenzie, AM; Patel, KR, 1976)
"In ten patients with extrinsic bronchial asthma, allergen provoked bronchospasm was significantly inhibited by the alpha receptor blocking drug thymoxamine given intravenously."1.25Effect of alpha receptor blocking drug, thymoxamine, on allergen induced bronchoconstriction in extrinsic asthma. ( Kerr, JW; Patel, KR, 1975)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199019 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patel, KR10
Turner, P1
Smith, SR1
Barnes, PJ1
Britton, J1
Ayres, J1
Cochrane, GM1
Kerr, JW6
MacDonald, EB1
MacKenzie, AM1
Wardle, EN1
Thomson, NC1
Haddock, AM1
Alston, WC2
Griffin, JP1
Kamburoff, PL1
Prime, FJ1
Arbab, AG1
Herxheimer, H1
Gaddie, J2
Skinner, C1
Palmer, KN2
Legge, JS1
Petrie, G1

Reviews

3 reviews available for moxisylyte and Asthma

ArticleYear
Some clinical implications of the receptor concept.
    Circulation research, 1980, Volume: 46, Issue:6 Pt 2

    Topics: Adrenergic Agonists; Angina Pectoris; Asthma; Epinephrine; Indoramin; Moxisylyte; Norepinephrine; Pe

1980
Alpha-adrenergic blocking agents in the treatment of asthma.
    Journal of clinical and hospital pharmacy, 1983, Volume: 8, Issue:2

    Topics: Adrenergic alpha-Antagonists; Asthma; Humans; Indoramin; Moxisylyte; Phentolamine; Receptors, Adrene

1983
The role of adrenoceptors in bronchial asthma.
    Journal of the Royal College of Physicians of London, 1979, Volume: 13, Issue:3

    Topics: Adenylyl Cyclases; Animals; Asthma; Humans; Isoproterenol; Lung; Moxisylyte; Phentolamine; Phenyleph

1979

Trials

5 trials available for moxisylyte and Asthma

ArticleYear
Effect of inhaled alpha-blocker on airflow obstruction in asthma.
    Journal of the Royal Society of Medicine, 1981, Volume: 74, Issue:9

    Topics: Adult; Aerosols; Aged; Asthma; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Moxisyly

1981
Letter: Alpha-receptor-blocking drugs in bronchial asthma.
    Lancet (London, England), 1975, Feb-08, Volume: 1, Issue:7902

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Airway Obstruction; Airway Resistance; Albut

1975
Atropine, sodium cromoglycate, and thymoxamine in PGF2 alpha-induced bronchoconstriction in extrinsic asthma.
    British medical journal, 1975, May-17, Volume: 2, Issue:5967

    Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Atropine; Bronchi; Bronchodilator Agents; Cr

1975
The effect of thymoxamine and cromolyn sodium on postexercise bronchoconstriction in asthma.
    The Journal of allergy and clinical immunology, 1976, Volume: 57, Issue:4

    Topics: Airway Obstruction; Asthma; Cromolyn Sodium; Forced Expiratory Volume; Humans; Moxisylyte; Physical

1976
Atropine or thymoxamine for chronic asthma.
    British medical journal, 1977, Apr-23, Volume: 1, Issue:6068

    Topics: Asthma; Atropine; Humans; Moxisylyte; Respiratory Function Tests

1977

Other Studies

11 other studies available for moxisylyte and Asthma

ArticleYear
Alpha-adrenoceptor blocking drugs in asthma.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:4

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Airway Resistance; Asthma; Cyclic AMP; Female; Huma

1976
Adrenergic receptors of normal and asthmatic airways.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Adrenergic alpha-Agonists; Albuterol; Asthma; Bronchial Spasm; Catecholamines; Dose-Response Relatio

1984
Effect of alpha receptor blocking drug, thymoxamine, on allergen induced bronchoconstriction in extrinsic asthma.
    Clinical allergy, 1975, Volume: 5, Issue:3

    Topics: Administration, Intranasal; Adolescent; Adult; Airway Resistance; Allergens; Asthma; Bronchial Spasm

1975
Effect of dopamine on airways conductance in normals and extrinsic asthmatics.
    British journal of clinical pharmacology, 1978, Volume: 5, Issue:5

    Topics: Adolescent; Adult; Aerosols; Airway Obstruction; Airway Resistance; Asthma; Dopamine; Humans; Infusi

1978
Response of lymphocyte guanyl cyclase to propranolol, noradrenaline, thymoxamine, and acetylcholine in extrinsic bronchial asthma.
    British medical journal, 1975, May-17, Volume: 2, Issue:5967

    Topics: Acetylcholine; Adolescent; Adult; Asthma; Bronchi; Cyclic AMP; Drug Synergism; Female; Guanylate Cyc

1975
Thymoxamine and airways obstruction.
    Lancet (London, England), 1972, Jun-10, Volume: 1, Issue:7763

    Topics: Adrenergic alpha-Antagonists; Airway Obstruction; Asthma; Humans; Moxisylyte; Sympatholytics; Terpen

1972
Thymoxamine in bronchial asthma.
    Lancet (London, England), 1972, Sep-02, Volume: 2, Issue:7775

    Topics: Animals; Asthma; Bronchodilator Agents; Humans; Moxisylyte; Sympatholytics; Terpenes

1972
Thymoxamine in bronchial asthma.
    Lancet (London, England), 1972, Sep-23, Volume: 2, Issue:7778

    Topics: Asthma; Histamine H1 Antagonists; Humans; Moxisylyte; Sympatholytics; Terpenes

1972
Response of leucocyte adenyl cyclase to isoprenaline and effect of alpha-blocking drugs in extrinsic bronchial asthma.
    British medical journal, 1974, Jan-19, Volume: 1, Issue:5898

    Topics: Acute Disease; Adenylyl Cyclases; Adolescent; Adrenergic alpha-Antagonists; Adult; Asthma; Drug Comb

1974
The airways response to phenylephrine after blockade of alpha and beta receptors in extrinsic bronchial asthma.
    Clinical allergy, 1973, Volume: 3, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Airway Resistance; Asthma; Humans; Isopro

1973
The effect of an alpha-adrenergic receptor blocking drug on histamine sensitivity in bronchial asthma.
    British journal of diseases of the chest, 1972, Volume: 66, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Asthma; Blood Pressure; Carbachol; Female; Histamine Anta

1972