morphine-chloride has been researched along with Ataxia* in 2 studies
2 other study(ies) available for morphine-chloride and Ataxia
| Article | Year |
|---|---|
Some 11-substituted tetrahydrocannabinols. Synthesis and comparison with the potent cannabinoid metabolites 11-hydroxytetrahydrocannabinols.
A series of compounds was prepared in which the 11-hydroxyl of 11-hydroxy-delta8-THC, the potent metabolite of delta8-THC, was replaced by a methyl, methyoxy, amino, or acetamido group. All of the compounds tested produced behavioral changes in dogs, but only the methoxy compound has analgesic properties in mice. An isosteric oxime was inactive in mice. Topics: Analgesics; Animals; Ataxia; Behavior, Animal; Dogs; Dronabinol; Mice; Structure-Activity Relationship | 1979 |
Some 9-hydroxycannabinoid-like compounds. Synthesis and evaluation of analgesic and behavioral properties.
A series of 9-hydroxylated cannabinoid-like compounds was prepared and tested for analgesic properties in mice and behavioral properties in dogs. Although the prototype compound, 9-nor-9-hydroxyhexahydrocannabinol, has potent antinociceptive activity in laboratory animals, the new analogues were relatively inactive. All of the compounds produced an alteration of behavior in unanesthetized dogs. Two of the compounds produced cannabinoid-like effects and the other two produced general CNS depression. Topics: Analgesics; Animals; Ataxia; Behavior, Animal; Cannabinoids; Dogs; Dronabinol; Mice; Reflex, Abnormal | 1979 |