morphine and Urethral-Diseases

Intraintestinal meconium calcification in the fetus and newborn is a rare finding, occurring in patients with intestinal obstruction. The intraluminal location of the enterolithiasis enables differentiation from calcifications that are secondary to bowel perforation and meconium peritonitis. We report on a term male neonate with VACTERL (vertebral defects, imperforate anus, cardiac anomalies, tracheoesophageal fistula, renal anomalies, limb anomalies) association and rectourethral fistula, in whom enterolithiasis was documented by prenatal ultrasound imaging at 21 weeks' gestation. A review of the literature and a summary of all previously described cases of neonates with intraluminal meconium calcifications are provided. Prenatal ultrasonographic detection of enterolithiasis in fetuses with anal atresia may indicate the presence of an enterourinary fistula.

Topics: Adult; Anus, Imperforate; Calcinosis; Colonic Diseases; Female; Humans; Infant, Newborn; Male; Meconium; Pregnancy; Rectal Fistula; Ultrasonography, Prenatal; Urethral Diseases; Urinary Fistula

Intraluminal meconium calculi are a rare cause of neonatal abdominal calcifications in patients with anorectal malformations. To investigate their pathogenesis, we performed infrared spectroscopic analysis of meconium-calcified lesions.. Meconium calculi were collected from the colostomy in a newborn patient with imperforate anus and rectourethral fistula. The potassium bromide method was employed to obtain the infrared absorption spectrum of the meconium calculi.. The wavelength pattern of the meconium calculi exhibited 4 specific peaks at 1570, 1390, 1105, and 1005 cm(-1) between 22% and 45% transmittance values. The unique absorption spectrum exclusively indicated ammonium hydrogen urate (C(5)N(5)O(3)H(7)), having the combined constituents of ammonium and uric acid.. These results suggest that the intraluminal meconium calculi were originally derived from meconium and fetal urine. The stasis of meconium passage and fetal urine mixing through the rectourethral fistula in a low-pH condition was deduced to be the main cause of this rare stone formation.

Topics: Anus, Imperforate; Calculi; Colon; Colonic Diseases; Humans; Infant, Newborn; Male; Meconium; Radiography; Rectal Fistula; Spectrophotometry, Infrared; Urethral Diseases; Urinary Fistula

Topics: Abdomen; Adolescent; Anemia; Child; Child, Preschool; Constipation; Diagnosis, Differential; Female; Guaiac; Humans; Infant, Newborn; Male; Meconium; Megacolon; Melena; Neuromuscular Diseases; Pain; Pediatrics; Posture; Rectal Diseases; Rectum; Sigmoidoscopy; Urethral Diseases; Vaginal Diseases