morphine and Pleural-Effusion

Topics: Adult; Aged; Cesarean Section; Female; Follow-Up Studies; Granuloma; Humans; Meconium; Middle Aged; Peritonitis; Pleural Effusion; Postoperative Complications

In a thirty-month prospective study pleural effusions were found on chest radiographs in 33 of 1482 newborns admitted to intensive care units. Congenital heart disease was the most common cause, accounting for eleven cases. Meconium aspiration was the most common respiratory disease associated with neonatal pleural effusion. Infants whose effusions were first noted after the second day of life were likely to have heart disease (p = 0.02). Infants with moderate or large effusions were unlikely to have heart disease (p = 0.04). Prolonged pleural effusion was associated with a prolonged need for supplemental oxygen. Survivors whose effusions lasted three or more days were at increased risk for needing supplemental oxygen for more than twenty-one days (p = 0.07). The overall mortality was 48 percent (sixteen of thirty-three infants died).

Topics: Cardiovascular Diseases; Heart Defects, Congenital; Humans; Infant, Newborn; Lung; Lung Diseases; Meconium; Pleural Effusion; Pneumonia; Prognosis; Prospective Studies; Radiography; Risk; Streptococcus agalactiae

A 32-year-old woman underwent cesarean section because of fetal distress. Meconium spilled into the incision during delivery. The patient subsequently had a fever, right-sided pleuritic chest pain, a right lower lobe infiltrate, and a pleural effusion. Exploratory laparotomy disclosed intra-abdominal fibrosis with inflammatory mass formation. A biopsy specimen showed a granulomatous reaction around the bile-staining material similar to meconium. The patient was treated with prednisone, and her symptoms abated. During the next four years, episodes of fever, abdominal discomfort, and pleuritis recurred, which eventually responded to indomethacin therapy.

Topics: Adult; Cesarean Section; Female; Fetal Distress; Humans; Infant, Newborn; Meconium; Omentum; Peritonitis; Pleural Effusion; Pregnancy

Aspiration of meconium produces respiratory distress of various severity and outcome. To evaluate whether the initial chest roentgenogram (0 to 8 hours of age) can be used to predict the outcome, an analysis of 80 cases with clinical and roentgenographic features of aspiration syndrome was undertaken. Infiltration was seen in 62, consolidation or atelectasis in 44, hyperinflation in 37, air leak in 25, pleural effusion in 16, and increased cardiothymic shadow in 16. Consolidation or atelectasis, most commonly associated with thick meconium aspiration, appeared to be the most significant determinant of poor outcome. Infants who had consolidation or atelectasis were more ill, had lower pH, higher fraction of inspired oxygen, higher alveolar-arterial oxygen gradients, and required longer duration of oxygen intake than those infants who had no consolidation or atelectasis. Thus, the initial chest roentgenogram can be used for predicting outcome in infants with meconium aspiration syndrome.

Topics: Humans; Infant, Newborn; Inhalation; Meconium; Pleural Effusion; Prognosis; Pulmonary Atelectasis; Radiography; Respiratory Distress Syndrome, Newborn

Human alpha fetoprotein (AFP) has been detected by the agar double diffusion method in ascitic fluid, cerebrospinal fluid (CSF) and bile, from fetuses, neonates and patients with AFP seropositive hepatocellular carcinoma. AFP was detected in the meconium and faeces of fetuses and neonates respectively. The protein was not detected in the amniotic fluid nor the pericardial fluid. It was found in the urine in only two fetuses that had concomittant renal disease. It was not detected in breast milk of lactating females. When metastases occurred in the lung from a hepatocellular carcinoma producing AFP, the pleural effusions sometimes contained AFP. The concentrations of AFP in the serum and in the other body fluids were about the same. This indicates that other body fluids can be used for the diagnosis of hepatocellular carcinoma.

Topics: Adult; Amniotic Fluid; Animals; Ascitic Fluid; Bile; Body Fluids; Carcinoma, Hepatocellular; Feces; Female; Fetal Proteins; Fetus; Humans; Immunodiffusion; Infant, Newborn; Liver Neoplasms; Lung Neoplasms; Meconium; Middle Aged; Milk, Human; Neoplasm Metastasis; Pericardial Effusion; Pleural Effusion; Rabbits

Topics: Absorption; Amniotic Fluid; Animals; Ascitic Fluid; Bile; Cattle; Cerebrospinal Fluid; Erythrocytes; Female; Fungi; Gastric Juice; Hemagglutination; Hemagglutination Inhibition Tests; Hemagglutination Tests; Humans; Intestinal Secretions; Meconium; Milk; Milk, Human; Ovarian Cysts; Papain; Pleural Effusion; Precipitin Tests; Saliva; Seeds; Snails; Swine; Synovial Fluid; Tears; Tissue Extracts

Topics: Humans; Infant, Newborn; Infant, Newborn, Diseases; Inhalation; Meconium; Mediastinal Emphysema; Pleural Effusion; Pneumothorax; Pulmonary Atelectasis; Radiography; Respiratory Distress Syndrome, Newborn; Respiratory Tract Diseases