morphine and Pain--Postoperative

morphine has been researched along with Pain--Postoperative* in 2 studies

Other Studies

2 other study(ies) available for morphine and Pain--Postoperative

ArticleYear
Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists.
    Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17

    Recently sulfamoyl benzamides were identified as a novel series of cannabinoid receptor ligands. Replacing the sulfonamide functionality and reversing the original carboxamide bond led to the discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB(2) agonists. Selective CB(2) agonist 31 (K(i)=2.7; CB(1)/CB(2)=190) displayed robust activity in a rodent model of postoperative pain.

    Topics: Animals; Anti-Inflammatory Agents; Benzamides; Cell Line; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Humans; Pain, Postoperative; Rats; Receptor, Cannabinoid, CB2; Stereoisomerism; Structure-Activity Relationship; Transfection

2009
Symptomatic maternal intraperitoneal meconium granulomata: report of two cases.
    Diagnostic gynecology and obstetrics, 1982,Summer, Volume: 4, Issue:2

    We present two cases of histologically proven maternal intraperitoneal granulomata following cesarean section delivery. One patient presented during the immediate postpartum period with clinical symptoms consistent with subphrenic abscess. The other patient required operative intervention for a suspected ruptured tubo-ovarian abscess. In both cases, microscopic examination of the tissue obtained at the time of reoperation showed granuloma reaction, lanugo hair, and fetal squamous cells consistent with meconium deposition. The authors conclude that meconium granuloma should enter the differential diagnosis in cesarean section patients with unexplained postoperative pain.

    Topics: Adult; Cesarean Section; Female; Foreign-Body Reaction; Granuloma; Humans; Meconium; Pain, Postoperative; Peritoneal Diseases; Pregnancy

1982