morphine and Ovarian-Cysts

Intra-abdominal cystic lesions are increasingly recognized in the newborn because of the advent of routine antenatal ultrasonography. As these lesions are often asymptomatic or non-specific in clinical presentation in the newborn, imaging by ultrasonography has an important role in diagnosis. We present a pictorial review of the commonly encountered intra-abdominal cystic lesions in the newborn, with emphasis on ultrasonographic features that can aid differentiation between the various lesions.

Topics: Abdomen; Choledochal Cyst; Cysts; Diagnosis, Differential; Female; Gastrointestinal Diseases; Humans; Infant, Newborn; Meconium; Mesenteric Cyst; Ovarian Cysts; Ultrasonography

Two monoclonal antibodies to human milk-fat globule membranes, which recognize an epithelial antigen designated MAM-3c, were found to bind strongly to epithelial glycoproteins derived from non-secretors. Further investigations, using purified glycoproteins and structurally defined oligosaccharides, established that the optimal antigenic structure for both antibodies involves the Type 1 based blood group antigen, Lea, in combination with the Type 2 based onco-developmental antigen, SSEA-1, (Formula: see text) as in lacto-N-difucohexaose II. The antibodies may also react with the corresponding monofucosyl structures lacking the 3- or 4- linked fucose residues and to a lesser extent with the afucosyl tetrasaccharide sequence as in lacto-N-tetraose. The Lea and SSEA-1 antigens are known to occur on human epithelial glycoproteins. However, this is the first report of an antigenic specificity involving a combination of the Type 1 and Type 2 based fuco-oligosaccharides and occurring on epithelial glycoproteins.

Topics: Antibodies, Monoclonal; Antibody Specificity; Antigens, Neoplasm; Carbohydrate Conformation; Carbohydrate Sequence; Digestive System; Epithelium; Epitopes; Female; Glycoproteins; Humans; Immunoglobulin A, Secretory; Lewis Blood Group Antigens; Meconium; Milk, Human; Oligosaccharides; Ovarian Cysts

This report demonstrates that a marker of human embryonic endoderm and embryonal carcinoma cells recognized by a hybridoma antibody FC 10.2, involves Type 1 blood group chains with the sequence Gal beta 1 leads to 3G1cNAc beta 1 leads to 3Gal beta 1 leads to 4G1c. This conclusion has been reached from antigenic analyses of meconium, ovarian cyst glycoproteins, oligosaccharides and glycolipids having Type 1 or Type 2 blood group chains. From knowledge of saccharide sequences and blood group related antigens in gastrointestinal tissues of man, we deduce that the 'disappearance' of FC 10.2 antigen from the normal, differentiated cells of the adult may result from masking by additional glycosylations or other substitutions.

Topics: Acetylglucosamine; Amino Acid Sequence; Antibodies, Monoclonal; Antigen-Antibody Reactions; Blood Group Antigens; Endoderm; Epitopes; Female; Galactose; Glycolipids; Glycoproteins; Humans; Meconium; Oligosaccharides; Ovarian Cysts

Topics: ABO Blood-Group System; Agglutinins; Animals; Binding Sites; Blood Group Antigens; Cold Temperature; Erythrocytes; Female; Glycoproteins; Humans; I Blood-Group System; Lewis Blood Group Antigens; Meconium; Oligosaccharides; Ovarian Cysts; Radioimmunoassay; Sheep; Time Factors

Topics: Absorption; Amniotic Fluid; Animals; Ascitic Fluid; Bile; Cattle; Cerebrospinal Fluid; Erythrocytes; Female; Fungi; Gastric Juice; Hemagglutination; Hemagglutination Inhibition Tests; Hemagglutination Tests; Humans; Intestinal Secretions; Meconium; Milk; Milk, Human; Ovarian Cysts; Papain; Pleural Effusion; Precipitin Tests; Saliva; Seeds; Snails; Swine; Synovial Fluid; Tears; Tissue Extracts

Topics: Abdomen, Acute; Cysts; Diagnosis, Differential; Digestive System Abnormalities; Female; Follow-Up Studies; Hemangioma; Humans; Hydronephrosis; Infant, Newborn; Infant, Newborn, Diseases; Kidney Diseases; Kidney Neoplasms; Liver Neoplasms; Male; Meconium; Neuroblastoma; Ovarian Cysts; Peritonitis; Polycystic Kidney Diseases; Renal Veins; Retroperitoneal Neoplasms; Stomach Neoplasms; Teratoma; Thrombophlebitis; Uterine Diseases; Vaginal Diseases