morphine and Esophageal-Atresia

Topics: Abnormalities, Multiple; Colonic Diseases; Digestive System Abnormalities; Duodenal Obstruction; Esophageal Atresia; Female; Hernia; Humans; Ileum; Infant, Newborn; Intestinal Atresia; Intestinal Obstruction; Intestines; Jejunum; Male; Meconium; Megacolon; Mesenteric Cyst; Polyhydramnios; Pregnancy; Pylorus; Radiography; Vitelline Duct

We report a patient with combination of esophageal atresia, proximal tracheoesophageal fistula and meconium peritonitis. These two rare disorders have different etiology, pathogenetic mechanisms and require different diagnostic manipulations and surgical treatments. The authors discuss the features of diagnosis and surgical treatment of this disease.. Представлен клинический случай сочетания атрезии пищевода с проксимальным трахеопищеводным свищом и мекониевого перитонита. Два редких заболевания, которые имеют разную этиологию и патогенетические механизмы развития, требуют различных диагностических манипуляций и оперативного лечения, описаны у одного ребенка. В статье отражены особенности диагностики и хирургического лечения ребенка.

Topics: Esophageal Atresia; Humans; Infant, Newborn; Meconium; Peritonitis; Rare Diseases; Tracheoesophageal Fistula

Cloacal malformations are rare anomalies, occurring in females, and in which they demonstrate a single perineal orifice for urethra, vagina, and rectum. Prenatal ultrasonograms (US) of cloacal malformations sometimes show ascites, hydrocolpos, and hydronephrosis. We herein describe the characteristic prenatal US and magnetic resonance imaging (MRI) findings of the cloacal malformations associated with meconium peritonitis.. The pre- and postnatal records of 11 newborn patients with cloacal malformations, treated in our hospital from 1988 to 2004, were reviewed. All fetuses underwent prenatal US by experienced obstetricians, whereas in addition, fetal MRI was performed in 1 patient.. The prenatal US and/or MRI findings showed fetal ascites, a multicystic pelvic mass, oligohydramnios, and bilateral hydronephrosis in 5 of 11 patients with cloacal malformations. In these 5 cases, postnatal examinations showed associated hydrocolpos, hydrometrocolpos, and bilateral hydronephrosis; furthermore, 4 of these 5 cases also showed meconium peritonitis at laparotomy.. The prenatal US and MRI findings, showing fetal ascites, multicystic pelvic mass, bilateral hydronephrosis, and oligohydraminios are highly suggestive of the cloacal malformations associated with meconium peritonitis.

Topics: Abdomen; Abnormalities, Multiple; Cloaca; Esophageal Atresia; Female; Gestational Age; Humans; Hydrocolpos; Hydronephrosis; Infant, Newborn; Magnetic Resonance Imaging; Meconium; Peritonitis; Prenatal Diagnosis; Ultrasonography, Prenatal; Uterus; Vagina

Topics: Duodenal Obstruction; Esophageal Atresia; Humans; Infant, Newborn; Intestinal Atresia; Male; Meconium; Peritonitis

Fecal alpha 1-antitrypsin is used as a marker for intestinal protein loss reflecting increased intestinal permeability. Exact data of fecal alpha 1-antitrypsin in newborn infants are not available.. 30 healthy mature neonates and three infants with impaired gastrointestinal passage due to stenoses and atresia respectively, were investigated during the first days of life. The amniotic fluid of 13 and the serum of 17 infants was available. alpha 1-antitrypsin was determined using the radial immunodiffusion method.. Normal newborns showed mean fecal alpha 1-antitrypsin levels (+/-SD) of 2061 +/- 817 mg/dl (day 1), 1186 +/- 720 mg/dl (day 2), 308 +/- 380 (day 3), 35 +/- 27 (day 5), and 27 +/- 21 mg/dl (day 6). Two infants with esophageal atresia presented a much lower pattern, and one with annular pancreas had a fecal alpha 1-antitrypsin pattern comparable with that of normal babies. Serum alpha 1-antitrypsin was normal (275 +/- 52 mg/dl), and amniotic fluid contained 20 +/- 12 mg/dl alpha 1-antitrypsin.. The pattern of neonatal fecal alpha 1-antitrypsin content appears to reflect the meconium clearance of the gut rather than intestinal permeability and "gut closure." We hypothesize that the origin of increased fecal alpha 1-antitrypsin is the result of accumulated secretions from bile, the pancreas, and the duodenum, but alpha 1-antitrypsin originating from swallowed amniotic fluid during pregnancy may play an additional role.

Topics: alpha 1-Antitrypsin; Amniotic Fluid; Esophageal Atresia; Feces; Female; Humans; Infant, Newborn; Intestinal Obstruction; Male; Meconium; Pancreas

Topics: Cystic Fibrosis; Esophageal Atresia; Humans; Infant, Newborn; Intestinal Obstruction; Intestines; Meconium; Megacolon; Prognosis

Topics: Esophageal Atresia; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Meconium; Peritonitis

Topics: Autopsy; Esophageal Atresia; Humans; Infant, Newborn; Male; Meconium; Peritonitis

Topics: Abnormalities, Multiple; Age Factors; Bile; Child; Child, Preschool; Down Syndrome; Duodenal Obstruction; Duodenum; Esophageal Atresia; Female; Humans; Infant; Infant, Newborn; Meconium; Polyhydramnios; Pregnancy; Vomiting

Topics: Anal Canal; Body Fluids; Body Water; Body Weight; Deuterium; Duodenum; Esophageal Atresia; Hernia, Umbilical; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Atresia; Intestinal Obstruction; Jejunum; Meconium; Megacolon; Radioisotope Dilution Technique; Rectum; Tracheoesophageal Fistula; Water

Topics: Duodenum; Emergencies; Esophageal Atresia; Female; Gastrointestinal Diseases; Hernia, Diaphragmatic; Hernia, Inguinal; Hernia, Umbilical; Hernia, Ventral; Hernias, Diaphragmatic, Congenital; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Atresia; Intestinal Obstruction; Intestinal Perforation; Jejunum; Meconium; Pneumothorax; Pregnancy; Pyloric Stenosis; Renal Veins; Rupture; Stomach Diseases; Thrombophlebitis

Topics: Anus, Imperforate; Cineradiography; Colostomy; Diatrizoate; Esophageal Atresia; Esophagus; Female; Humans; Infant, Newborn; Injections, Intraperitoneal; Male; Meconium; Spine; Tracheoesophageal Fistula; Urography

With the present-day development and understanding of anesthetic methods, fluid and electrolyte therapy, antibiotic medications and pediatric care, many congenital anomalies once uniformly fatal are now being successfully treated by emergency operations in the neonatal period. The eight most common of these which demand emergency operation in the immediate postnatal period are esophageal atresia and tracheoesophageal fistula, diaphragmatic hernia with dislocation of the abdominal viscera into the chest, malrotation of the intestine with obstruction, intestinal atresia, meconium ileus, imperforate anus, omphalocele and myelomeningocele. Although infants born with any of these serious problems often are born prematurely and often have more than one congenital anomaly, survival rates in the surgical treatment of these conditions are steadily improving. Early diagnosis and prompt treatment are the most important factors in the continued improvement of these survival rates.

Topics: Anus, Imperforate; Child; Esophageal Atresia; Fetal Diseases; Hernia, Diaphragmatic; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Atresia; Intestinal Obstruction; Meconium; Tracheoesophageal Fistula