morphine and Ductus-Arteriosus--Patent

Topics: Ductus Arteriosus, Patent; Humans; Ileal Diseases; Infant, Newborn; Infant, Premature; Intestinal Obstruction; Male; Meconium; Postoperative Complications; Radiography

Meconium obstruction (MO) of prematurity can result in increased morbidity or mortality and prolonged hospitalization if not diagnosed and treated appropriately.. The aims of our study were to identify the incidence and risk factors associated with MO and to review the treatment outcomes.. A retrospective analysis was undertaken of 101 extremely low birth weight infants (ELBWIs) who were born between January 1, 2007, and April 1, 2009, at Seoul National University Hospital. Prenatal and neonatal factors were compared between the MO and control groups. The treatment outcomes were also reviewed.. Twenty-two (22%) patients were diagnosed as having MO. Eighteen of these patients (82%) had prenatal risk factors for MO. Respiratory distress syndrome was more prevalent in the MO group than in the control group (p = 0.001). Overall, 17 of the 22 patients (77%) were relieved with medical treatment and the rest underwent ileostomy. The times to full enteral feeding did not differ between the medically treated group and the control group. However, the surgically treated group required more time to achieve full enteral feeding, and some patients had persistent gastrointestinal problems.. MO is not a rare condition in ELBWIs, and the majority of ELBWIs have prenatal risk factors. Medical management was effective, and medically manageable cases had good prognoses for subsequent feeding, whereas some surgically managed cases had persistent gastrointestinal problems.

Topics: Adult; Comorbidity; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ileostomy; Infant, Extremely Low Birth Weight; Infant, Newborn; Intensive Care Units, Neonatal; Intestinal Obstruction; Male; Meconium; Placental Insufficiency; Pregnancy; Republic of Korea; Respiratory Distress Syndrome, Newborn; Retrospective Studies; Sex Ratio; Ultrasonography, Prenatal

Three patients with Meconium Aspiration Syndrome (S.A.M.) and severe hypoxemia are reported. From the first hours of life they needed mechanical ventilation, showing no improvement in PaO2 in spite of usual respiratory support measures. In one case, pulmonary hypertension and ductal right to left shunt through ductus arteriosus and foramen ovale was objetivated by cardiac catheterization. Following intravenous prefusion of a pulmonary vasodilator (Tolazoline) patients showed a clinical amelioration and a definite increase in PaO2. Results and evolution with the use of this drug are commented.

Topics: Ductus Arteriosus, Patent; Female; Humans; Hyaline Membrane Disease; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; Injections, Intravenous; Male; Meconium; Oxygen; Partial Pressure; Tolazoline

This is a case report of meconium ileus complicated by intestinal volvulus and infarction in a black infant.

Topics: Black People; Colon; Cystic Fibrosis; Ductus Arteriosus, Patent; Female; Humans; Ileostomy; Ileum; Infant; Infant, Newborn; Intestinal Obstruction; Intestine, Small; Jejunum; Meconium; Pregnancy

Topics: Abdominal Muscles; Abnormalities, Multiple; Colon; Ductus Arteriosus, Patent; Female; Heart Septal Defects, Ventricular; Humans; Infant, Newborn; Intestine, Small; Meconium; Prostheses and Implants; Respiratory Insufficiency; Transposition of Great Vessels