morphine and Bradycardia

The objective of the study was to evaluate, in labors complicated by thick meconium-stained amniotic fluid, the association between specific fetal heart rate (FHR) patterns and adverse perinatal outcomes.. A retrospective cohort study of patients with FHR tracing data (n = 1638) from a previously reported randomized controlled trial of amnioinfusion for the prevention of meconium aspiration syndrome.. The presence of FHR tracing abnormalities was associated with an increased risk of perinatal mortality and/or neonatal morbidity (moderately abnormal: adjusted odds ratio [OR], 1.67; 95% confidence interval [CI], 1.18-2.37; markedly abnormal: adjusted OR, 2.97; 95% CI, 1.88-4.67). Specific abnormalities that were associated with the risk of perinatal mortality and/or neonatal morbidity included prolonged decelerations (OR, 1.22; 95% CI, 1.02-1.48), severe variable decelerations (OR, 1.08; 95% CI, 1.00-1.16), bradycardia (OR, 2.49; 95% CI, 1.02-6.11), and tachycardia (OR, 2.43; 95% CI, 1.49-3.94).. The presence of abnormal FHR tracing patterns in meconium-stained amniotic fluid patients is associated with an increased risk of adverse perinatal outcomes.

Topics: Adult; Amniotic Fluid; Bradycardia; Cohort Studies; Female; Fetal Distress; Fetal Monitoring; Heart Rate, Fetal; Humans; Meconium; Morbidity; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Tachycardia; Young Adult

Topics: Amniotic Fluid; Bradycardia; Humans; Infant, Newborn; Intubation, Intratracheal; Meconium; Meconium Aspiration Syndrome; Positive-Pressure Respiration; Practice Guidelines as Topic; Resuscitation; Suction

A biphasic fetal heart rate variable deceleration pattern (W-sign) was investigated and found to be significantly associated with a greater length of umbilical cord (73.07 +/- 17.1 cm) than was found in patients without this pattern (56.47 +/- 11.4 cm) during the first stage of labor (P less than .001). The possible etiology of this variable deceleration pattern and its relative benignity are discussed.

Topics: Bradycardia; Electrocardiography; Female; Fetal Heart; Fetal Monitoring; Heart Rate; Humans; Meconium; Pregnancy; Umbilical Cord

Topics: Amniotic Fluid; Apgar Score; Bradycardia; Cesarean Section; Female; Humans; Infant, Newborn; Inhalation; Meconium; Mediastinal Emphysema; Nose; Obstetric Labor Complications; Oxygen; Pharynx; Pneumothorax; Pregnancy; Respiration; Respiratory Distress Syndrome, Newborn; Trachea; Vacuum Extraction, Obstetrical

Topics: Acid-Base Equilibrium; Amniotic Fluid; Apgar Score; Bradycardia; Female; Fetal Heart; Fetus; Humans; Infant, Newborn; Labor, Induced; Meconium; Oxygen Consumption; Oxytocin; Parity; Pregnancy; Prostaglandins; Uterus

Topics: Acidosis; Apgar Score; Blood Specimen Collection; Bradycardia; Carbon Dioxide; Delivery, Obstetric; Female; Fetal Diseases; Gestational Age; Heart Rate; Humans; Hydrogen-Ion Concentration; Hypoxia; Infant, Newborn; Inhalation; Meconium; Methods; Monitoring, Physiologic; Oxygen; Pregnancy; Prognosis; Prospective Studies; Scalp; Tachycardia

Topics: Amniotic Fluid; Animals; Bradycardia; Female; Fetal Diseases; Fetal Heart; Humans; Infant Mortality; Infant, Newborn; Maternal Mortality; Meconium; Pregnancy

Topics: Asphyxia Neonatorum; Bradycardia; Delivery, Obstetric; Female; Fetal Death; Fetal Diseases; Fetal Distress; Fetal Heart; Humans; Infant, Newborn; Meconium; Placenta; Pregnancy

Topics: Atropine; Bradycardia; Electrocardiography; Female; Fetal Diseases; Fetal Heart; Heart Auscultation; Heart Rate, Fetal; Humans; Hypoxia; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Obstetric Labor Complications; Oxygen Inhalation Therapy; Pregnancy; Tachycardia