morphinans and Angina-Pectoris

morphinans has been researched along with Angina-Pectoris* in 1 studies

Other Studies

1 other study(ies) available for morphinans and Angina-Pectoris

Article	Year
Hemodynamic and respiratory effects of morphine and butorphanol. Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:3 The hemodynamic effects of butorphanol, a potent synthetic narcotic-antagonist analgesic, were investigated and compared with those of morphine. A total of 20 patients were studied (8 butorphanol, 12 morphine) at the time of diagnostic cardiac catheterization. Butorphanol decreased pH, PCO2, and systemic artery pressure and increased PCO2, cardiac index, and pulmonary artery pressure. Morphine caused similar changes in pH, PO2, systemic artery pressure, and PCO2 but much smaller changes in cardiac index and no change in pulmonary artery pressure. The clinical implications and possible mechanisms are discussed. Topics: Adult; Analgesics; Angina Pectoris; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Morphinans; Morphine; Narcotic Antagonists; Respiration; Time Factors	1978

Article

Year

Hemodynamic and respiratory effects of morphine and butorphanol.

Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:3

The hemodynamic effects of butorphanol, a potent synthetic narcotic-antagonist analgesic, were investigated and compared with those of morphine. A total of 20 patients were studied (8 butorphanol, 12 morphine) at the time of diagnostic cardiac catheterization. Butorphanol decreased pH, PCO2, and systemic artery pressure and increased PCO2, cardiac index, and pulmonary artery pressure. Morphine caused similar changes in pH, PO2, systemic artery pressure, and PCO2 but much smaller changes in cardiac index and no change in pulmonary artery pressure. The clinical implications and possible mechanisms are discussed.

Topics: Adult; Analgesics; Angina Pectoris; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Morphinans; Morphine; Narcotic Antagonists; Respiration; Time Factors

1978