morin has been researched along with Skin-Neoplasms* in 1 studies
1 other study(ies) available for morin and Skin-Neoplasms
| Article | Year |
|---|---|
Inhibitory effect of flavonoid derivatives on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
To search for possible anti-tumor promoters, ten flavonoid derivatives (1-10) synthesized from morin and quercetin were examined for their inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation by a short-term in vitro assay. Of these compounds, pentaallyl ethers (9, 10) showed significant inhibitory effects on EBV-EA activation induced by the tumor promoter, 12-O-tetradecanoylphorbol 13-acetate. Further, quercetin pentaallyl ether (10) exhibited remarkable inhibitory effects on mouse skin tumor promotion in an in vivo two-stage carcinogenesis test. Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Female; Flavonoids; Herpesvirus 4, Human; Lymphocytes; Mice; Mice, Inbred ICR; Models, Chemical; Papilloma; Quercetin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2001 |