morin has been researched along with Atherosclerosis* in 2 studies
2 other study(ies) available for morin and Atherosclerosis
| Article | Year |
|---|---|
The anti-inflammatory effects of Morin hydrate in atherosclerosis is associated with autophagy induction through cAMP signaling.
Although the previous trials of inflammation have indicated that morin hydrate (MO) hold considerable promise, understanding the distinct mechanism of MO against inflammation remains a challenge.. Our results suggest that anti-AS and anti-inflammatory effects of MO are largely associated with its induction of autophagy through stimulation of cAMP-PKA-AMPK-SIRT1 signaling pathway. Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Autophagy; Cells, Cultured; Cyclic AMP; Flavonoids; Lipids; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Tumor Necrosis Factor-alpha | 2017 |
Influence of flavonols as in vitro on low density lipoprotein glycation.
The non-enzymatic glycation of Low density lipoprotein (LDL) is a naturally occurring chemical modification of apolipoprotein B as a result of condensation between lysine residues and glucose. Glycated LDL is poorly recognized by LDL receptors and initiates different processes that can be considered proatherogenic. Thus, LDL glycation may contribute in the increased atherosclerotic risk of patients with diabetes. The objective of this study was to investigate the effect of naturally occurring flavonols on LDL glycation in vitro.. In this study, LDL was isolated from EDTA-plasma by ultracentrifugation using a single step discontinuous gradient. Then, glucose was added to LDL and LDL glycation level was estimated in absence and presence of flavonols by sodium periodate assay.. This study was showed that five flavonols: quercetin, myricetin, kaempferol, rutin and morin decreased LDL glycation in a dose-dependent manner. Also, it was demonstrated this nutrients decreased electrophoretic mobility of glycated LDL.. The results of this investigation show that flavonols probably with their antioxidant properties inhibited LDL glycation and thus may have a role in ameliorating atherosclerotic risk of patients with diabetes mellitus. Topics: Adult; Antioxidants; Atherosclerosis; Diabetic Angiopathies; Flavonoids; Flavonols; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Kaempferols; Lipoproteins, LDL; Male; Quercetin; Rutin | 2007 |