montelukast and Glioma

montelukast has been researched along with Glioma* in 1 studies

Other Studies

1 other study(ies) available for montelukast and Glioma

Article	Year
[Effects of agonist and antagonist of cysteinyl leukotriene receptors on differentiation of rat glioma C6 cells]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2011, Volume: 40, Issue:2 To investigate the role of cysteinyl leukotriene (CysLT) receptors in the differentiation of rat glioma C6 cells.. Rat glioma C6 cells were treated with the agonist LTD(4), the CysLT(1) receptor antagonist montelukast and the differentiation inducer forskolin. Cell morphology and GFAP protein expression were determined after treatments.. Forskolin (10 μmol/L) induced morphological changes and GFAP protein expression (cell differentiation) in C6 cells, but LTD(4) (0.1-100 nmol/L) did not induce these changes. Montelukast (1 μmol/L) alone did not affect C6 cell differentiation, while it induced the differentiation when combined with the LTD(4) (100 nmol/L).. The CysLT(2) receptor may modulate the differentiation of rat glioma C6 cells. Topics: Acetates; Animals; Cell Differentiation; Cell Line, Tumor; Colforsin; Cyclopropanes; Cysteine; Glioma; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Quinolines; Rats; Receptors, Leukotriene; Sulfides	2011

Article

Year

[Effects of agonist and antagonist of cysteinyl leukotriene receptors on differentiation of rat glioma C6 cells].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2011, Volume: 40, Issue:2

To investigate the role of cysteinyl leukotriene (CysLT) receptors in the differentiation of rat glioma C6 cells.. Rat glioma C6 cells were treated with the agonist LTD(4), the CysLT(1) receptor antagonist montelukast and the differentiation inducer forskolin. Cell morphology and GFAP protein expression were determined after treatments.. Forskolin (10 μmol/L) induced morphological changes and GFAP protein expression (cell differentiation) in C6 cells, but LTD(4) (0.1-100 nmol/L) did not induce these changes. Montelukast (1 μmol/L) alone did not affect C6 cell differentiation, while it induced the differentiation when combined with the LTD(4) (100 nmol/L).. The CysLT(2) receptor may modulate the differentiation of rat glioma C6 cells.

Topics: Acetates; Animals; Cell Differentiation; Cell Line, Tumor; Colforsin; Cyclopropanes; Cysteine; Glioma; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Quinolines; Rats; Receptors, Leukotriene; Sulfides

2011