monorden and Carcinoma--Squamous-Cell

monorden has been researched along with Carcinoma--Squamous-Cell* in 1 studies

Other Studies

1 other study(ies) available for monorden and Carcinoma--Squamous-Cell

ArticleYear
Halohydrin and oxime derivatives of radicicol: synthesis and antitumor activities.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:11

    Novel halohydrin and oxime derivatives of radicicol (1) were prepared and evaluated for their v-src tyrosine kinase inhibitory, antiproliferative, and antitumor activities. Some of the resulting derivatives showed significantly improved antitumor activities than those of 1 in vitro as tested in a cell proliferation assay and in vivo using sc-inoculated human breast carcinoma and epidermoid tumor models. Design and synthesis of radicicol-based novel affinity probes are also described.

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Indicators and Reagents; Lactones; Macrolides; Oximes; src-Family Kinases; Structure-Activity Relationship; Tumor Cells, Cultured

2002