Page last updated: 2024-10-21

monomethylpropion and Chemical Dependence

monomethylpropion has been researched along with Chemical Dependence in 29 studies

monomethylpropion: metabolite of dimethylpropion; structure given in first source
2-methylamino-1-phenylpropan-1-one : An aromatic ketone that is propiophenone in which the hydrogen alpha- to the keto group has been replaced by a methylamino group.
methcathinone : A racemate comprising equal amounts of (R)- and (S)-methcathinone.

Research Excerpts

ExcerptRelevanceReference
" This paper describes a case of reiterated coma due to an overdose of methcathinone dissolved in alcohol that was taken with bromazepam."3.73Methcathinone: a new postindustrial drug. ( Belhadj-Tahar, H; Sadeg, N, 2005)
"Methylenedioxymethamphetamine (MDMA) and methcathinone (MCAT) are abused psychostimulant drugs that produce adverse effects in human users that include hepatotoxicity and death."1.56High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone. ( Chen, Y; Hall, FS; Saber, YH; Tran, HTN, 2020)
"A permanent Parkinsonian syndrome occurs in intravenous abusers of the designer psychostimulant methcathinone (ephedrone)."1.43Grey matter abnormalities in methcathinone abusers with a Parkinsonian syndrome. ( Donaghy, M; Ilves, P; Johansen-Berg, H; Juurmaa, J; Menke, RA; Müürsepp, A; Nigul, M; Stagg, CJ; Stepens, A; Taba, P; Tomberg, T; Vila, P, 2016)
"In ephedrone-induced parkinsonism a prominent mixed hyperkinetic-hypokinetic dysarthria occurs that appears related to marked dystonia and bradykinesia and probably reflects manganese induced toxic and neurodegenerative damage to the globus pallidus internus and substantia nigra."1.40A distinct variant of mixed dysarthria reflects parkinsonism and dystonia due to ephedrone abuse. ( Bonnet, C; Brožová, H; Janelidze, M; Khatiashvili, I; Megrelishvili, M; Okujava, M; Rusz, J; Růžička, E; Sekhniashvili, M; Tolosa, E, 2014)
"Patients with ephedrone parkinsonism (EP) show a complex, rapidly progressive, irreversible, and levodopa non-responsive parkinsonian and dystonic syndrome due to manganese intoxication."1.40Eye movements in ephedrone-induced parkinsonism. ( Bergquist, J; Bonnet, C; Botchorishvili, N; Brožová, H; Fiala, O; Gaymard, B; Hanuška, J; Janelidze, M; Jech, R; Kapianidze, M; Khatiashvili, I; Matoušková, O; Megrelishvili, M; Mikeladze, N; Nikolai, T; Okujava, M; Rivaud-Péchoux, S; Roth, J; Rusz, J; Růžička, E; Serranová, T; Sieger, T, 2014)
"A new form of presumed manganese poisoning has been reported in drug-addicted persons from Russia, Ukraine, and Estonia who have intravenously injected self-prepared methcathinone hydrochloride (Ephedrone)."1.34Manganese-induced Parkinsonism associated with methcathinone (Ephedrone) abuse. ( de Bie, RM; Gladstone, RM; Ko, JH; Lang, AE; Strafella, AP, 2007)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (27.59)18.2507
2000's5 (17.24)29.6817
2010's13 (44.83)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Zeng, N1
Zheng, H1
Shi, T1
Zhang, HB1
Wang, LX1
Liang, ZY1
Sun, B1
Liao, Y1
Rao, LL1
Yang, B1
Yuan, TF1
Chen, Y1
Tran, HTN1
Saber, YH1
Hall, FS1
Kałwa, A1
Bonano, JS1
Glennon, RA3
De Felice, LJ1
Banks, ML3
Negus, SS3
Rusz, J2
Megrelishvili, M2
Bonnet, C2
Okujava, M2
Brožová, H2
Khatiashvili, I2
Sekhniashvili, M1
Janelidze, M2
Tolosa, E1
Růžička, E2
Koksal, A2
Keskinkılıc, C1
Sozmen, MV1
Dirican, AC1
Aysal, F1
Altunkaynak, Y1
Baybas, S2
Sieger, T1
Matoušková, O1
Nikolai, T1
Hanuška, J1
Kapianidze, M1
Mikeladze, N1
Botchorishvili, N1
Serranová, T1
Fiala, O1
Roth, J1
Bergquist, J5
Jech, R1
Rivaud-Péchoux, S1
Gaymard, B1
Suyama, JA1
Sakloth, F1
Kolanos, R1
Lazenka, MF1
Asser, A2
Kõks, S1
Snellman, A1
Haaparanta-Solin, M1
Arponen, E1
Grönroos, T1
Nairismägi, J1
Soomets, U1
Piip, P1
Eltermaa, M1
Sauk, M1
Lindmäe, H1
Rinne, JO1
Taba, P5
Dukat, M1
Juurmaa, J1
Menke, RA1
Vila, P1
Müürsepp, A1
Tomberg, T1
Ilves, P1
Nigul, M1
Johansen-Berg, H2
Donaghy, M2
Stagg, CJ2
Stepens, A2
Yildirim, EA1
Eşsizoğlu, A1
Doğu, B1
Gökalp, P1
Sikk, K3
Haldre, S3
Nyholm, D2
Askmark, H1
Danfors, T1
Sörensen, J1
Thurfjell, L1
Raininko, R1
Eriksson, R1
Flink, R1
Färnstrand, C1
Aquilonius, SM3
Platkajis, A1
Boudrias, MH1
McGraw, M1
McGraw, L1
Paris, M1
Roose, Ä1
Petterson, J1
Eriksson, SL1
Belhadj-Tahar, H1
Sadeg, N1
Zjablov, G1
Asser, T1
de Bie, RM1
Gladstone, RM1
Strafella, AP1
Ko, JH1
Lang, AE1
Sanotsky, Y1
Lesyk, R1
Fedoryshyn, L1
Komnatska, I1
Matviyenko, Y1
Fahn, S1
Kaminski, BJ1
Griffiths, RR1
Gorgaslidze, AG1
Saĭfullaeva, MA1
Kuz'mina, MM1
Golitsina, LS1
Smetnev, AS1
Emerson, TS1
Cisek, JE1
Rosen, DS1
Goldstone, MS1
Schechter, MD1
O'Dea, PJ1
Murphy, B1
Balzer, C1
Kochetkova, EA1
Sherstiuk, BV1
Gel'tser, BI1

Reviews

1 review available for monomethylpropion and Chemical Dependence

ArticleYear
[Cardiorespiratory disorders in drug addiction].
    Terapevticheskii arkhiv, 1998, Volume: 70, Issue:12

    Topics: Adolescent; Adult; Animals; Asthma; Cocaine-Related Disorders; Heart Diseases; Humans; Lung Diseases

1998

Other Studies

28 other studies available for monomethylpropion and Chemical Dependence

ArticleYear
Impaired delay discounting and time sensitivity in methcathinone use disorder.
    European archives of psychiatry and clinical neuroscience, 2022, Volume: 272, Issue:8

    Topics: Decision Making; Delay Discounting; Humans; Impulsive Behavior; Male; Reward; Substance-Related Diso

2022
High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 192

    Topics: Ammonia; Animals; Brain; Central Nervous System Stimulants; Disease Models, Animal; Female; Glutamic

2020
Characteristic of neuropsychological deficits in patients diagnosed with manganese encephalopathy due to ephedrone use - case series analysis.
    Psychiatria polska, 2020, Apr-30, Volume: 54, Issue:2

    Topics: Adult; Brain Diseases; Cognition Disorders; Female; Humans; Male; Manganese Poisoning; Middle Aged;

2020
Abuse-related and abuse-limiting effects of methcathinone and the synthetic "bath salts" cathinone analogs methylenedioxypyrovalerone (MDPV), methylone and mephedrone on intracranial self-stimulation in rats.
    Psychopharmacology, 2014, Volume: 231, Issue:1

    Topics: Animals; Benzodioxoles; Brain; Conditioning, Operant; Data Interpretation, Statistical; Designer Dru

2014
A distinct variant of mixed dysarthria reflects parkinsonism and dystonia due to ephedrone abuse.
    Journal of neural transmission (Vienna, Austria : 1996), 2014, Volume: 121, Issue:6

    Topics: Acoustics; Adult; Analysis of Variance; Antiparkinson Agents; Dysarthria; Dystonia; Humans; Magnetic

2014
Evaluation of cognitive characteristics of patients developing manifestations of parkinsonism secondary to long-term ephedrone use.
    European neurology, 2014, Volume: 71, Issue:3-4

    Topics: Adult; Cognition Disorders; Humans; Male; Manganese Poisoning; Neuropsychological Tests; Parkinsonia

2014
Eye movements in ephedrone-induced parkinsonism.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Adult; Basal Ganglia; Brain; Eye Movements; Female; Humans; Male; Manganese; Middle Aged; Parkinsoni

2014
Abuse-Related Neurochemical Effects of Para-Substituted Methcathinone Analogs in Rats: Microdialysis Studies of Nucleus Accumbens Dopamine and Serotonin.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 356, Issue:1

    Topics: Amphetamine; Animals; Behavior, Animal; Designer Drugs; Dopamine; Dopamine Plasma Membrane Transport

2016
Increased striatal VMAT2 binding in mice after chronic administration of methcathinone and manganese.
    Brain research, 2016, 12-01, Volume: 1652

    Topics: Animals; Autoradiography; Biomechanical Phenomena; Carbon Radioisotopes; Central Nervous System Stim

2016
Decoding the Structure of Abuse Potential for New Psychoactive Substances: Structure-Activity Relationships for Abuse-Related Effects of 4-Substituted Methcathinone Analogs.
    Current topics in behavioral neurosciences, 2017, Volume: 32

    Topics: Amphetamine; Animals; Behavior, Animal; Dopamine Plasma Membrane Transport Proteins; Fenfluramine; H

2017
Structure-Activity Relationships of Synthetic Cathinones.
    Current topics in behavioral neurosciences, 2017, Volume: 32

    Topics: Adrenergic Uptake Inhibitors; Alkaloids; Amphetamines; Animals; Central Nervous System Stimulants; D

2017
Grey matter abnormalities in methcathinone abusers with a Parkinsonian syndrome.
    Brain and behavior, 2016, Volume: 6, Issue:11

    Topics: Adult; Atrophy; Brain; Case-Control Studies; Female; Gray Matter; Humans; Magnetic Resonance Imaging

2016
[Chronic manganese intoxication due to methcathinone (ephedron) abuse: a case report].
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2009,Fall, Volume: 20, Issue:3

    Topics: Adult; Antisocial Personality Disorder; Back Pain; Basal Ganglia Diseases; Conversion Disorder; Diag

2009
Clinical, neuroimaging and neurophysiological features in addicts with manganese-ephedrone exposure.
    Acta neurologica Scandinavica, 2010, Volume: 121, Issue:4

    Topics: Adult; Basal Ganglia Diseases; Corpus Striatum; Female; Humans; Magnetic Resonance Imaging; Male; Ma

2010
White matter abnormalities in methcathinone abusers with an extrapyramidal syndrome.
    Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 12

    Topics: Adult; Basal Ganglia Diseases; Brain; Data Interpretation, Statistical; Diffusion Magnetic Resonance

2010
Bath salts: not as harmless as they sound.
    Journal of emergency nursing, 2012, Volume: 38, Issue:6

    Topics: Adult; Alkaloids; Central Nervous System Stimulants; Drug and Narcotic Control; Emergencies; Househo

2012
Manganese-induced parkinsonism in methcathinone abusers: bio-markers of exposure and follow-up.
    European journal of neurology, 2013, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Biomarkers; Cohort Studies; Estonia; Female; Follow-Up Studies; Hair; Humans; Mal

2013
Methcathinone: a new postindustrial drug.
    Forensic science international, 2005, Oct-04, Volume: 153, Issue:1

    Topics: Adult; Amphetamines; Anti-Anxiety Agents; Bromazepam; Central Nervous System Depressants; Central Ne

2005
Irreversible motor impairment in young addicts--ephedrone, manganism or both?
    Acta neurologica Scandinavica, 2007, Volume: 115, Issue:6

    Topics: Adult; Brain; Central Nervous System Stimulants; Disability Evaluation; Disease Progression; Dyskine

2007
Manganese-induced Parkinsonism associated with methcathinone (Ephedrone) abuse.
    Archives of neurology, 2007, Volume: 64, Issue:6

    Topics: Adult; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Manganese Poisoning; Parkinsonian D

2007
Manganic encephalopathy due to "ephedrone" abuse.
    Movement disorders : official journal of the Movement Disorder Society, 2007, Jul-15, Volume: 22, Issue:9

    Topics: Adult; Basal Ganglia; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Manganese Poisoning;

2007
Intravenous self-injection of methcathinone in the baboon.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Illicit Drugs; Injections, Int

1994
[Cardiac arrhythmia and myocardial contraction in opium and ephedrone addiction].
    Kardiologiia, 1993, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Echocardiography; Electrocardiography; Electrocardiography,

1993
Methcathinone: a Russian designer amphetamine infiltrates the rural midwest.
    Annals of emergency medicine, 1993, Volume: 22, Issue:12

    Topics: Adult; Animals; Designer Drugs; Female; Humans; Lethal Dose 50; Male; Mice; Michigan; Poisoning; Pro

1993
Methcathinone.
    The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 1993, Volume: 14, Issue:6

    Topics: Adult; Humans; Michigan; Propiophenones; Substance-Related Disorders

1993
'Cat': methcathinone--a new drug of abuse.
    JAMA, 1993, May-19, Volume: 269, Issue:19

    Topics: Humans; Propiophenones; Substance-Related Disorders

1993
Drug-drug discrimination: stimulus properties of drugs of abuse upon a serotonergic-dopaminergic continuum.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:1

    Topics: Amphetamine; Animals; Discrimination, Psychological; Dopamine; Dopamine Agonists; Dopamine Uptake In

1997
Traffic and illegal production of drugs in rural America.
    NIDA research monograph, 1997, Volume: 168

    Topics: Cannabis; Crack Cocaine; Humans; Methamphetamine; Propiophenones; Rural Health; Substance-Related Di

1997