Page last updated: 2024-10-21

monomethylpropion and Brain Disorders

monomethylpropion has been researched along with Brain Disorders in 9 studies

monomethylpropion: metabolite of dimethylpropion; structure given in first source
2-methylamino-1-phenylpropan-1-one : An aromatic ketone that is propiophenone in which the hydrogen alpha- to the keto group has been replaced by a methylamino group.
methcathinone : A racemate comprising equal amounts of (R)- and (S)-methcathinone.

Research Excerpts

ExcerptRelevanceReference
" Seventeen patients initially were treated with trihexyphenidyl in dosage 10 mg daily with switching to biperiden after 3 months."2.78[The use of biperiden (akineton) in patients with ephedrone encephalopathy]. ( Datieva, VK; Levin, OS, 2013)
"Manganese encephalopathy is a known disorder in occupational medicine."1.62Manganese Encephalopathy Caused by Homemade Methcathinone (Ephedrone) Prevalence in Poland. ( Habrat, B; Klimkiewicz, A; Silczuk, A, 2021)
"The patients had a parkinsonian syndrome with symmetrical bradykinesia, dystonias, and postural, gait and speech impairment, with moderate restrictions in activities of daily living."1.56Cognitive profile of patients with manganese-methcathinone encephalopathy. ( Ennok, M; Haldre, S; Sikk, K; Taba, P, 2020)
"A number of cases of severe parkinsonism-dystonia have been recognized and reported following the illicit use of ephedrone prepared from pseudoephedrine and potassium permanganate."1.56Neuropathological Findings in Ephedrone Encephalopathy. ( Dziewulska, D; Fedoryshyn, L; Holton, JL; Kuzyk, P; Lees, AJ; Matviyenko, Y; Sanotsky, Y; Selikhova, M; Semeryak, O, 2020)
"A new form of presumed manganese poisoning has been reported in drug-addicted persons from Russia, Ukraine, and Estonia who have intravenously injected self-prepared methcathinone hydrochloride (Ephedrone)."1.34Manganese-induced Parkinsonism associated with methcathinone (Ephedrone) abuse. ( de Bie, RM; Gladstone, RM; Ko, JH; Lang, AE; Strafella, AP, 2007)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's5 (55.56)2.80

Authors

AuthorsStudies
Ordak, M1
Sloniewicz, N1
Nasierowski, T1
Muszynska, E1
Bujalska-Zadrozny, M1
Habrat, B2
Silczuk, A1
Klimkiewicz, A1
Ennok, M1
Sikk, K1
Haldre, S1
Taba, P1
Sanotsky, Y2
Selikhova, M1
Fedoryshyn, L2
Kuzyk, P1
Matviyenko, Y2
Semeryak, O1
Dziewulska, D1
Holton, JL1
Lees, AJ1
Kałwa, A1
Levin, OS1
Datieva, VK1
Baran-Furga, H1
Sienkiewicz-Jarosz, H1
Sein Anand, J1
Poniatowska, R1
de Bie, RM1
Gladstone, RM1
Strafella, AP1
Ko, JH1
Lang, AE1
Lesyk, R1
Komnatska, I1
Fahn, S1

Reviews

2 reviews available for monomethylpropion and Brain Disorders

ArticleYear
Manganese concentration in patients with encephalopathy following ephedrone use: a narrative review and analysis of case reports.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:1

    Topics: Brain Diseases; Humans; Ions; Manganese; Manganese Poisoning; Propiophenones

2022
[Encephalopathy caused by intravenous potassium permanganate used for illegal production of methcathinone (ephedrone) from medicines containing pseudoephedrine].
    Przeglad lekarski, 2013, Volume: 70, Issue:8

    Topics: Brain Chemistry; Brain Diseases; Chelation Therapy; Humans; Injections, Intravenous; Magnetic Resona

2013

Trials

1 trial available for monomethylpropion and Brain Disorders

ArticleYear
[The use of biperiden (akineton) in patients with ephedrone encephalopathy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2013, Volume: 113, Issue:8

    Topics: Biperiden; Brain Diseases; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Follow-Up S

2013

Other Studies

6 other studies available for monomethylpropion and Brain Disorders

ArticleYear
Manganese Encephalopathy Caused by Homemade Methcathinone (Ephedrone) Prevalence in Poland.
    Nutrients, 2021, Oct-03, Volume: 13, Issue:10

    Topics: Brain Diseases; Humans; Manganese Poisoning; Poland; Prevalence; Propiophenones; Substance Abuse, In

2021
Cognitive profile of patients with manganese-methcathinone encephalopathy.
    Neurotoxicology, 2020, Volume: 76

    Topics: Adolescent; Adult; Brain Diseases; Cognition; Cognitive Dysfunction; Female; Humans; Male; Manganese

2020
Neuropathological Findings in Ephedrone Encephalopathy.
    Movement disorders : official journal of the Movement Disorder Society, 2020, Volume: 35, Issue:10

    Topics: Adult; Brain Diseases; Female; Humans; Manganese Poisoning; Parkinsonian Disorders; Propiophenones

2020
Characteristic of neuropsychological deficits in patients diagnosed with manganese encephalopathy due to ephedrone use - case series analysis.
    Psychiatria polska, 2020, Apr-30, Volume: 54, Issue:2

    Topics: Adult; Brain Diseases; Cognition Disorders; Female; Humans; Male; Manganese Poisoning; Middle Aged;

2020
Manganese-induced Parkinsonism associated with methcathinone (Ephedrone) abuse.
    Archives of neurology, 2007, Volume: 64, Issue:6

    Topics: Adult; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Manganese Poisoning; Parkinsonian D

2007
Manganic encephalopathy due to "ephedrone" abuse.
    Movement disorders : official journal of the Movement Disorder Society, 2007, Jul-15, Volume: 22, Issue:9

    Topics: Adult; Basal Ganglia; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Manganese Poisoning;

2007