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monoisoamyl-2,3-dimercaptosuccinate and Arsenic Encephalopathy

monoisoamyl-2,3-dimercaptosuccinate has been researched along with Arsenic Encephalopathy in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (47.37)29.6817
2010's8 (42.11)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Flora, SJS; Jain, K; Panghal, A; Patwa, J1
Flora, SJS; Kumar, P; Naqvi, S1
Flora, SJS; Kushwaha, P; Samim, M; Yadav, A1
Flora, SJ; Ram Kumar, M; Reddy, GR1
Babbar, AK; Flora, SJ; Kaushik, MP; Kushwaha, P; Lomash, V; Mathur, R; Mishra, AK; Pathak, U; Samim, M; Yadav, A1
Flora, SJ; Gupta, R; Kushwah, P; Mishra, D; Pant, SC; Satish, HT1
Bhatt, K; Dwivedi, N; Flora, SJ; Kushwah, PK; Pachauri, V1
Binukumar, BK; Dwivedi, N; Flora, SJ; Gill, KD; Mehta, A; Yadav, A1
Bhadauria, S; Flora, SJ; Pachauri, V; Yadav, A1
Acharya, S; Basu, AK; Bhattacharya, D; Chatterjee, S; Chaudhuri, S; Dasgupta, S; Flora, SJ; Kumar, P; Singh, MK1
Flora, SJ; Mehta, A; Mishra, D; Pachauri, V1
Flora, SJ; Jaiswal, DK; Kannan, GM; Pant, BP1
Bhaskar, AS; Dube, SN; Flora, SJ; Kannan, GM; Mehta, A; Pant, BP; Rao, PV1
Flora, SJ; Kannan, GM1
Bhadauria, S; Flora, SJ2
Bhadauria, S; Dhaked, RK; Flora, SJ; Pant, SC1
Flora, SJ; Modi, M1
Bhadauria, S; Flora, SJ; Kannan, GM; Singh, N1

Reviews

2 review(s) available for monoisoamyl-2,3-dimercaptosuccinate and Arsenic Encephalopathy

ArticleYear
Chemistry, Pharmacology, and Toxicology of Monoisoamyl Dimercaptosuccinic Acid: A Chelating Agent for Chronic Metal Poisoning.
    Chemical research in toxicology, 2022, 10-17, Volume: 35, Issue:10

    Topics: Animals; Antidotes; Antioxidants; Arsenic; Arsenic Poisoning; Cadmium; Chelating Agents; Heavy Metal Poisoning; Mercury; Rats; Rats, Wistar; Succimer

2022
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
    Journal of environmental biology, 2007, Volume: 28, Issue:2 Suppl

    Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation Therapy; Dimercaprol; Drug Therapy, Combination; Environmental Pollutants; Humans; Melatonin; Oxidative Stress; Plant Extracts; Selenium; Succimer; Taurine; Thioctic Acid; Vitamin E; Zinc

2007

Other Studies

17 other study(ies) available for monoisoamyl-2,3-dimercaptosuccinate and Arsenic Encephalopathy

ArticleYear
Comparative efficacy of Nano and Bulk Monoisoamyl DMSA against arsenic-induced neurotoxicity in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 132

    Topics: Animals; Antioxidants; Arsenic Poisoning; Arsenites; Behavior, Animal; Biomarkers; Brain; Chelating Agents; Disease Models, Animal; Drug Compounding; Lipids; Male; Motor Activity; Nanoparticles; Oxidative Stress; Rats, Transgenic; Sodium Compounds; Succimer

2020
Combinatorial drug delivery strategy employing nano-curcumin and nano-MiADMSA for the treatment of arsenic intoxication in mouse.
    Chemico-biological interactions, 2018, Apr-25, Volume: 286

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Arsenic; Arsenic Poisoning; Curcumin; Deoxyguanosine; Drug Carriers; Drug Synergism; Enzymes; Glutathione; Liver; Male; Mice; Nanoparticles; Oxidative Stress; Reactive Oxygen Species; Succimer

2018
Monoisoamyl 2,3-dimercaptosuccinic acid attenuates arsenic induced toxicity: behavioral and neurochemical approach.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:1

    Topics: Animals; Arsenic Poisoning; Behavior, Animal; Brain; Catalase; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hand Strength; Male; Maze Learning; Mitochondria; Motor Activity; Neuroprotective Agents; Rats; Rats, Wistar; Succimer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2013
Nanoencapsulation of DMSA monoester for better therapeutic efficacy of the chelating agent against arsenic toxicity.
    Nanomedicine (London, England), 2014, Volume: 9, Issue:4

    Topics: Animals; Arsenic; Arsenic Poisoning; Brain; Chelating Agents; Drug Carriers; Kidney; Liver; Male; Mice; Nanoparticles; Rabbits; Rats; Rats, Wistar; Succimer

2014
Co-administration of monoisoamyl dimercaptosuccinic acid and Moringa oleifera seed powder protects arsenic-induced oxidative stress and metal distribution in mice.
    Toxicology mechanisms and methods, 2009, Volume: 19, Issue:2

    Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Body Weight; Brain; Chelating Agents; Drinking; Eating; Free Radicals; Glutathione; Kidney; Liver; Male; Metals; Mice; Moringa oleifera; Oxidative Stress; Seeds; Succimer; Tissue Distribution

2009
Co-administration of meso 2,3-dimercaptosuccinic acid monoesters reduces arsenic concentration and oxidative stress in gallium arsenide exposed rats.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:7

    Topics: Aminolevulinic Acid; Animals; Arsenic; Arsenic Poisoning; Arsenicals; Catalase; Copper; Gallium; Glutathione; Heme; Kidney; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Superoxide Dismutase; Transaminases; Zinc

2011
MiADMSA reverses impaired mitochondrial energy metabolism and neuronal apoptotic cell death after arsenic exposure in rats.
    Toxicology and applied pharmacology, 2011, Nov-01, Volume: 256, Issue:3

    Topics: Animals; Apoptosis; Arsenic Poisoning; Brain; Cells, Cultured; Chelating Agents; Electron Transport; Electron Transport Complex IV; Energy Metabolism; Male; Membrane Potential, Mitochondrial; Mitochondria; NADH Dehydrogenase; Neurons; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Succinate Dehydrogenase

2011
Monoisoamyl 2, 3-dimercaptosuccinic acid (MiADMSA) demonstrates higher efficacy by oral route in reversing arsenic toxicity: a pharmacokinetic approach.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:5

    Topics: Administration, Oral; Animals; Arsenic; Arsenic Poisoning; Chelating Agents; Chronic Disease; Copper; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Kidney; Liver; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer; Zinc

2012
Therapeutic profile of T11TS vs. T11TS+MiADMSA: a hunt for a more effective therapeutic regimen for arsenic exposure.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:6

    Topics: Animals; Apoptosis; Arsenic; Arsenic Poisoning; CD2 Antigens; Cell Transformation, Neoplastic; Chelating Agents; Chelation Therapy; Cytokines; Drug Therapy, Combination; Environmental Exposure; Lymphocytes; Mice; Oxidative Stress; Succimer

2012
Arsenic induced neuronal apoptosis in guinea pigs is Ca2+ dependent and abrogated by chelation therapy: role of voltage gated calcium channels.
    Neurotoxicology, 2013, Volume: 35

    Topics: Animals; Apoptosis; Arsenic Poisoning; Arsenites; bcl-2-Associated X Protein; Calcium; Calcium Channels, L-Type; Caspase 3; Chelating Agents; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; Guinea Pigs; Kinetics; Male; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sodium Compounds; Succimer

2013
The efficacy of monoisoamyl ester of dimercaptosuccinic acid in chronic experimental arsenic poisoning in mice.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2003, Volume: 38, Issue:1

    Topics: Administration, Oral; Animals; Arsenic Poisoning; Disease Models, Animal; Infusions, Parenteral; Kidney; Liver; Male; Mice; Oxidative Stress; Succimer

2003
Therapeutic potential of monoisoamyl and monomethyl esters of meso 2,3-dimercaptosuccinic acid in gallium arsenide intoxicated rats.
    Toxicology, 2004, Feb-15, Volume: 195, Issue:2-3

    Topics: Aminolevulinic Acid; Animals; Antidotes; Arsenic Poisoning; Arsenicals; Biomarkers; Chelating Agents; Chelation Therapy; Comet Assay; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Gallium; Injections, Intraperitoneal; Liver; Male; Protoporphyrins; Rats; Rats, Wistar; Succimer; Treatment Outcome

2004
Chronic arsenic poisoning in the rat: treatment with combined administration of succimers and an antioxidant.
    Ecotoxicology and environmental safety, 2004, Volume: 58, Issue:1

    Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Brain Chemistry; Chelating Agents; Drug Interactions; Drug Therapy, Combination; Heme; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer; Tissue Distribution

2004
Arsenic induced inhibition of delta-aminolevulinate dehydratase activity in rat blood and its response to meso 2,3-dimercaptosuccinic acid and monoisoamyl DMSA.
    Biomedical and environmental sciences : BES, 2004, Volume: 17, Issue:1

    Topics: Administration, Oral; Animals; Arsenic Poisoning; Arsenicals; Enzyme Inhibitors; Injections, Intraperitoneal; Male; Mice; Porphobilinogen Synthase; Rats; Succimer

2004
Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats.
    Life sciences, 2005, Sep-16, Volume: 77, Issue:18

    Topics: 5-Aminolevulinate Synthetase; Animals; Arsenic; Arsenic Poisoning; Chelating Agents; DNA Damage; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Male; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Unithiol

2005
Response of arsenic-induced oxidative stress, DNA damage, and metal imbalance to combined administration of DMSA and monoisoamyl-DMSA during chronic arsenic poisoning in rats.
    Cell biology and toxicology, 2007, Volume: 23, Issue:2

    Topics: Animals; Antidotes; Arsenic Poisoning; Chelating Agents; Copper; DNA Damage; Drug Therapy, Combination; Erythrocytes; Kidney; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer; Zinc

2007
Combined administration of iron and monoisoamyl-DMSA in the treatment of chronic arsenic intoxication in mice.
    Cell biology and toxicology, 2007, Volume: 23, Issue:6

    Topics: Animals; Arsenic; Arsenic Poisoning; Brain; Chronic Disease; Drug Therapy, Combination; Iron; Kidney; Liver; Male; Mice; Oxidative Stress; Succimer; Zinc

2007