monocrotophos has been researched along with Abnormalities--Drug-Induced* in 2 studies
2 other study(ies) available for monocrotophos and Abnormalities--Drug-Induced
Article | Year |
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Teratism induced in the developing chick by RPR-V, an organophosphate.
Fertile White Leghorn chicken eggs were injected on day 4 of incubation with 0, 0.25, 0.50 or 1.00 mg RPR-V/egg and opened on day 20 or allowed to hatch. The following parameters were examined: hatchability, growth and development, external malformations and skeletal deformities. As the dose was increased, the hatchability decreased, and the incidence of deformities increased. Staining of the skeleton with Alizarin red showed clear deformities in the embryos. The results suggest that RPR-V has teratogenic effects on chick embryos when injected on day 4 of incubation. Topics: Abnormalities, Drug-Induced; Animals; Anthraquinones; Chick Embryo; Dose-Response Relationship, Drug; Insecticides; Monocrotophos; Sulfhydryl Compounds; Teratogens | 1992 |
Temporal, morphological, and genetic responses of avian embryos to Azodrin, an organophosphate insecticide.
The effect of Azodrin on avian development was studied using a bobwhite quail line and two chicken lines--a single comb White Leghorn (SCWL) and an Australorp line. The bobwhite quail embryos did not respond to injections of Azodrin until stages 22 to 23 (6 days of incubation); the SCWL embryos, not until stage 18 (3 days of incubation) with increasing susceptibility through stage 20. The threshold concentration, at stage 19, for the SCWL was 0.4 mg/kg, for the Australorp, less. Within one hour of treatment stage-20 embryo shape was altered. There was, however, no immediate response from embryos treated earlier. The effect appeared as a reduced growth rate in the cervical flexure, and may be mediated by interference with the normal energy balance. The response, once initiated, was continuous through 10 days of incubation. Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Dose-Response Relationship, Drug; Eggs; Insecticides; Monocrotophos; Quail; Species Specificity; Time Factors | 1977 |