monocrotaline pyrrole and Hypertension, Pulmonary
monocrotaline pyrrole has been researched along with Hypertension, Pulmonary in 59 studies
Research
Studies (59)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 18 (30.51) | 18.7374 |
1990's | 21 (35.59) | 18.2507 |
2000's | 8 (13.56) | 29.6817 |
2010's | 9 (15.25) | 24.3611 |
2020's | 3 (5.08) | 2.80 |
Authors
Authors | Studies |
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Gu, L; Liu, CJ; Liu, HM; Xie, L; Yu, L | 1 |
Dong, J; Jiang, P; Jiang, XM; Li, L; Li, M; Luo, J; Ran, H; Xie, DJ; Zhang, PY; Zhou, L | 1 |
Bu, D; Chen, S; Du, J; Huang, Y; Jin, H; Kong, W; Liu, X; Tang, C; Tang, X; Tao, Y; Wang, X; Yang, G; Yu, W; Zhang, D; Zhang, H | 1 |
Chen, S; Jiang, X; Li, L; Luo, J; Wang, J; Zhang, J; Zhou, L | 1 |
Liu, WH; Liu, ZH; Luo, Q; Wang, Y; Xi, QY; Xu, XH; Zhang, HL; Zhao, ZH | 1 |
Dupuis, J; Fang, J; Hu, Q; Jing, ZC; Li, J; Lu, Y; Luo, S; Su, Y; Wang, T; Xiao, R; Zhang, J; Zhu, L | 1 |
Cheng, G; Lu, Y; Luan, Y; Zhang, Z | 1 |
Berry, GJ; Kao, PN; Nishimura, T; Pearl, RG; Qiao, L; Sessions, D; Shi, L; Thrasher, A; Trudell, JR | 1 |
Congxin, H; Qingyan, Z; Shengbo, Y; Wei, H; Xiaozhan, W; Xuejun, J; Xule, W; Yanhong, T; Zixuan, D; Zongwen, G | 1 |
Dai, Z; Guo, Z; Hu, W; Huang, C; Jiang, X; Tang, Y; Wang, X; Yang, B; Yu, S; Zhang, S; Zhao, Q | 1 |
Chen, JZ; Hu, XS; Liu, SK; Ma, CY; Wang, XX; Xia, L; Zeng, CL | 1 |
Dony, E; Dumitrascu, R; Ghofrani, HA; Grimminger, F; Koebrich, S; Pullamsetti, SS; Samidurai, A; Savai, R; Schermuly, RT; Seeger, W; Traupe, H; Weissmann, N | 1 |
Chen, JZ; Fu, GS; Qiu, FY; Wang, XX; Xia, L; Xie, XD; Yang, Y; Zhu, JH | 1 |
Lu, Y; Luan, Y; Wang, YB; Wei, DE; Zhang, ZH | 1 |
Chen, D; Chen, F; Dong, L; Ge, J; Guan, L; Qian, J; Zhou, D | 1 |
Austin, DJ; Elefteriades, JA; Goldstein, L; Keane, J; Kopf, GS; Lovoulos, C; Rocco, E; Singh, S; Tang, P; Tittle, S | 1 |
Gewitz, M; Huang, J; Mathew, R; Patel, K; Sehgal, PB; Shah, M | 1 |
Adnot, S; Barlier-Mur, AM; Eddahibi, S; Guignabert, C; Hamon, M; Hanoun, N; Izikki, M; Li, Z; Rodman, D; Tu, LI; Zadigue, P | 1 |
Adnot, S; Eddahibi, S; Giraudier, S; Hulin, A; Maitre, B; Marcos, E; Raoul, W; Saber, G; Vainchenker, W; Wagner-Ballon, O | 1 |
Mukhopadhyay, S; Patel, K; Sehgal, PB; Shah, M; Tuder, RM; Xu, F | 1 |
Bruner, LH; Hilliker, KS; Roth, RA | 1 |
Bell, TG; Deyo, JA; Hilliker, KS; Roth, RA | 1 |
Gamble, W; Meyrick, B; Reid, L | 1 |
Bell, TG; Hilliker, KS; Roth, RA | 1 |
Bell, TG; Hilliker, KS; Lorimer, D; Roth, RA | 1 |
Okada, K; Okada, M; Yamashita, C | 4 |
Pan, LC; Segall, HJ; Wilson, DW | 1 |
Emeis, JJ; Roth, RA; Schultze, AE | 1 |
Ito, O; Kasukawa, R; Koike, H; Miyata, M; Nishimaki, T; Nishio, S; Sakuma, F; Sekine, H; Ueno, Y | 1 |
Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P | 5 |
Bittner, HB; Chen, EP; Craig, DM; Davis, RD; Van Trigt, P | 1 |
Bittner, HB; Chen, EP; Craig, D; Davis, RD; Tull, F; Van Trigt, P | 1 |
Nohara, H; Okada, K; Okada, M; Wakiyama, H; Yamagishi, H; Yamashita, C | 1 |
Biswas, SS; Bittner, HB; Chen, EP; Davis, RD; Tull, F; Van Trigt, P | 1 |
Kakusaka, I; Kasahara, Y; Kitada, M; Kiyatake, K; Kuriyama, T; Ohmori, S; Sugito, K; Tatsumi, K; Yamagata, S | 1 |
Akhter, SA; Bittner, HB; Chen, EP; Davis, RD; Koch, WJ; Van Trigt, P | 1 |
Johnson, WD; Lalich, JL; Raczniak, TJ; Shumaker, RC | 1 |
Reindel, JF; Roth, RA | 1 |
Ganey, PE; Reindel, JF; Roth, RA; Slocombe, RF; Wagner, JG | 1 |
Roth, RA; Wagner, JG; White, SM | 1 |
Ganey, PE; Roth, RA | 5 |
Roth, RA; White, SM | 1 |
Altiere, RJ; Gillespie, MN; Olson, JW | 1 |
Ganey, PE; Roth, RA; Sprugel, KH; Wagner, JG; White, SM | 1 |
Bruner, LH; Johnson, KJ; Roth, RA; Till, GO | 1 |
Bruner, LH; Bull, RW; Roth, RA | 1 |
Hilliker, KS; Roth, RA | 1 |
Reviews
1 review(s) available for monocrotaline pyrrole and Hypertension, Pulmonary
Article | Year |
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Lung vascular injury from monocrotaline pyrrole, a putative hepatic metabolite.
Topics: Animals; Biotransformation; Endothelium, Vascular; Hypertension, Pulmonary; Liver; Lung; Monocrotaline; Pyrrolizidine Alkaloids | 1991 |
Other Studies
58 other study(ies) available for monocrotaline pyrrole and Hypertension, Pulmonary
Article | Year |
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[Pulmonary Vascular Remodeling Characteristics of Pulmonary Arterial Hypertension Mouse Model Induced by Left Pneumonectomy and Jugular Vein Injection of Monocrotaline Pyrrole].
Topics: Animals; Disease Models, Animal; Hypertension, Pulmonary; Jugular Veins; Male; Mice; Mice, Inbred C57BL; Monocrotaline; Neointima; Pneumonectomy; Pulmonary Arterial Hypertension; Pulmonary Artery; Vascular Remodeling | 2022 |
Establishment of a canine model of pulmonary arterial hypertension induced by dehydromonocrotaline and ultrasonographic study of right ventricular remodeling.
Topics: Animals; Dimethylformamide; Dogs; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Pulmonary Arterial Hypertension; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling | 2023 |
Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation.
Topics: Animals; Cells, Cultured; Cysteine; Cytokines; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Humans; Hydrogen Sulfide; Hypertension, Pulmonary; I-kappa B Kinase; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Male; Monocrotaline; NF-kappa B; Pulmonary Artery; Rats, Wistar; Signal Transduction | 2019 |
Sympathetic innervation of canine pulmonary artery and morphometric and functional analysis in dehydromonocrotaline-induced models after pulmonary artery denervation.
Topics: Animals; Disease Models, Animal; Dogs; Hypertension, Pulmonary; Lung; Monocrotaline; Pulmonary Artery; Sympathectomy; Sympathetic Nervous System; Vascular Resistance | 2020 |
Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension.
Topics: Animals; Blood Pressure; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Mevalonic Acid; Monocrotaline; Polyisoprenyl Phosphates; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Signal Transduction; Simvastatin; Vascular Remodeling | 2018 |
Monocrotaline pyrrole induces pulmonary endothelial damage through binding to and release from erythrocytes in lung during venous blood reoxygenation.
Topics: Animals; Endothelial Cells; Endothelium; Erythrocytes; Hypertension, Pulmonary; Lung; Monocrotaline; Oxygen; Rats; Rats, Sprague-Dawley | 2019 |
[Research on effects of bone marrow mononuclear cells implantation on model of experimental pulmonary artery hypertension].
Topics: Animals; Bone Marrow Cells; Cell Transplantation; Dogs; Familial Primary Pulmonary Hypertension; Female; Hypertension, Pulmonary; Leukocytes, Mononuclear; Male; Monocrotaline; Rats | 2013 |
Endothelial fate mapping in mice with pulmonary hypertension.
Topics: Actins; Alkylating Agents; Animals; Antigens, CD; Cadherins; Cell Lineage; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Humans; Hypertension, Pulmonary; Integrases; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monocrotaline; Neointima; Pneumonectomy; Pulmonary Artery; von Willebrand Factor | 2014 |
Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension.
Topics: Angiotensin II; Animals; Collagen; Dimethylformamide; Dinoprostone; Dogs; Echocardiography; Electrocardiography; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Kidney; Lung; Male; Monocrotaline; Neurotransmitter Agents; Random Allocation; Renal Artery; Renin-Angiotensin System; Sympathectomy; Vascular Remodeling | 2015 |
[Beneficial effects of renal denervation on pulmonary vascular remodeling in experimental pulmonary artery hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dogs; Echocardiography; Endothelin-1; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Kidney; Lung; Monocrotaline; Pulmonary Artery; Sympathectomy; Vascular Remodeling | 2015 |
[Quantitative and functional changes of circulating endothelial progenitor cells in dogs with dehydromonocrotaline-induced pulmonary artery hypertension].
Topics: Animals; Cell Count; Cells, Cultured; Disease Models, Animal; Dogs; Endothelial Cells; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Stem Cells | 2008 |
Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Injections, Subcutaneous; Lung; Lung Compliance; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Monocrotaline; Neutrophils; Rats; Rats, Sprague-Dawley; Survival Rate | 2008 |
Senescent endothelial progenitor cells from dogs with pulmonary arterial hypertension: a before-after self-controlled study.
Topics: Animals; Cell Culture Techniques; Cell Separation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Dogs; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Hypertension, Pulmonary; Male; Monocrotaline; Neovascularization, Physiologic; Stem Cells | 2009 |
Effects of autologous bone marrow mononuclear cells implantation in canine model of pulmonary hypertension.
Topics: Animals; Bone Marrow Transplantation; Cell Differentiation; Cell Separation; Cell Tracking; Disease Models, Animal; Dogs; Endothelial Cells; Endothelin-1; Flow Cytometry; Fluorescent Antibody Technique; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-6; Monocrotaline; Neovascularization, Physiologic; Pulmonary Artery; RNA, Messenger; Stem Cell Transplantation; Time Factors; Transplantation, Autologous; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Ventricular Function, Right | 2012 |
Atorvastatin prevents dehydromonocrotaline-induced pulmonary hypertension in beagles.
Topics: Alkylating Agents; Animals; Atorvastatin; Cell Proliferation; Cytokines; Dogs; Endothelium, Vascular; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Pyrroles | 2012 |
Right ventricle-sparing heart transplantation effective against iatrogenic pulmonary hypertension.
Topics: Alkylating Agents; Animals; Dogs; Heart Transplantation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Iatrogenic Disease; Monocrotaline | 2004 |
Disruption of endothelial-cell caveolin-1alpha/raft scaffolding during development of monocrotaline-induced pulmonary hypertension.
Topics: Animals; Caveolin 1; Caveolins; Disease Models, Animal; DNA-Binding Proteins; Endothelial Cells; Endothelium, Vascular; Heat-Shock Proteins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isomerases; Male; Membrane Microdomains; Mitosis; Monocrotaline; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Pulmonary Artery; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Trans-Activators; von Willebrand Factor | 2004 |
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.
Topics: Acute Disease; Animals; Blood Pressure; Blood Vessels; Humans; Hydroxyindoleacetic Acid; Hypertension, Pulmonary; Hypoxia; Lung; Mice; Mice, Transgenic; Monocrotaline; Muscle, Smooth, Vascular; Pulmonary Artery; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution; Transgenes; Vasoconstriction; Ventricular Function, Right | 2006 |
Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Disease Models, Animal; Female; Green Fluorescent Proteins; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monocrotaline; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Artery; Stem Cell Transplantation; Stem Cells; Time Factors; Ventricular Function, Right; Ventricular Pressure | 2007 |
Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.
Topics: Animals; Cattle; Caveolin 1; Cell Compartmentation; Cells, Cultured; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Lysosomes; Male; Monocrotaline; Muscle, Smooth, Vascular; Protein Disulfide-Isomerases; Protein Transport; Rats; STAT3 Transcription Factor | 2008 |
Pulmonary hypertension and ECG changes from monocrotaline pyrrole in the rat.
Topics: Animals; Blood Cell Count; Body Weight; Cardiomegaly; Electrocardiography; Heart; Heart Ventricles; Hypertension, Pulmonary; Kinetics; Lung; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1983 |
Aggregation of platelets from monocrotaline pyrrole-treated rats.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Hypertension, Pulmonary; Male; Monocrotaline; Platelet Aggregation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Development of Crotalaria pulmonary hypertension: hemodynamic and structural study.
Topics: Animals; Blood Gas Analysis; Body Temperature; Cardiomegaly; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Pyrroles; Pyrrolizidine Alkaloids; Rats | 1980 |
Monocrotaline pyrrole-induced pulmonary hypertension in fawn-hooded rats with platelet storage pool deficiency: 5-hydroxytryptamine uptake by isolated, perfused lungs.
Topics: Animals; Blood Cell Count; Blood Platelets; Heart; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Organ Size; Perfusion; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin | 1983 |
Effects of thrombocytopenia on monocrotaline pyrrole-induced pulmonary hypertension.
Topics: Animals; Blood Platelets; Body Weight; Hypertension, Pulmonary; Immune Sera; Lung; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Thrombocytosis | 1984 |
[Pulmonary lobe transplantation in pulmonary hypertensive dogs under cardiopulmonary bypass].
Topics: Animals; Cardiopulmonary Bypass; Dogs; Hypertension, Pulmonary; Lung Transplantation; Monocrotaline | 1995 |
Establishment of canine pulmonary hypertension with dehydromonocrotaline. Importance of larger animal model for lung transplantation.
Topics: Animals; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Pulmonary; Lung Transplantation; Monocrotaline; Pulmonary Artery; Rats | 1995 |
A dehydromonocrotaline-induced pulmonary hypertension model in the beagle.
Topics: Animals; Disease Models, Animal; Dogs; Hypertension, Pulmonary; Monocrotaline | 1995 |
Role of endothelin-1 in beagles with dehydromonocrotaline-induced pulmonary hypertension.
Topics: Animals; Azepines; Dogs; Endothelins; Hemodynamics; Hypertension, Pulmonary; Indoles; Monocrotaline; Peptides, Cyclic; Viper Venoms | 1995 |
Endothelin receptor antagonists in a beagle model of pulmonary hypertension: contribution to possible potential therapy?
Topics: Alprostadil; Animals; Azepines; Dogs; Endothelin Receptor Antagonists; Hemodynamics; Hypertension, Pulmonary; Indoles; Monocrotaline; Nitroglycerin; Peptides, Cyclic; Pulmonary Circulation | 1995 |
Strain differences in the response of Fischer 344 and Sprague-Dawley rats to monocrotaline induced pulmonary vascular disease.
Topics: Animals; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Species Specificity; Weight Gain | 1993 |
Cellular fibronectin and von Willebrand factor concentrations in plasma of rats treated with monocrotaline pyrrole.
Topics: Animals; Endothelium, Vascular; Fibronectins; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Time Factors; von Willebrand Factor | 1996 |
Protective effect of beraprost sodium, a stable prostacyclin analogue, in development of monocrotaline-induced pulmonary hypertension.
Topics: Alprostadil; Animals; Endothelium, Vascular; Epoprostenol; Hypertension, Pulmonary; Interleukin-1; Interleukin-6; Male; Mice; Monocrotaline; Platelet Aggregation Inhibitors; Poisons; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1996 |
Right ventricular failure--insights provided by a new model of chronic pulmonary hypertension.
Topics: Administration, Inhalation; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Infusions, Intravenous; Milrinone; Monocrotaline; Nitric Oxide; Pulmonary Artery; Pyridones; Vascular Resistance; Vasodilator Agents; Ventricular Dysfunction, Right; Ventricular Function, Right | 1997 |
Pulmonary hemodynamics and blood flow characteristics in chronic pulmonary hypertension.
Topics: Animals; Blood Flow Velocity; Chronic Disease; Disease Models, Animal; Dogs; Fourier Analysis; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Pulmonary Wedge Pressure; Signal Processing, Computer-Assisted; Ultrasonography; Vascular Resistance | 1997 |
Milrinone improves pulmonary hemodynamics and right ventricular function in chronic pulmonary hypertension.
Topics: Animals; Cardiotonic Agents; Chronic Disease; Dogs; Fourier Analysis; Hypertension, Pulmonary; Milrinone; Monocrotaline; Pulmonary Circulation; Pulmonary Wedge Pressure; Pyridones; Signal Processing, Computer-Assisted; Ultrasonography; Vascular Resistance; Vasodilator Agents; Ventricular Function, Right | 1997 |
Nitric oxide improves pulmonary vascular impedance, transpulmonary efficiency, and left ventricular filling in chronic pulmonary hypertension.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Fourier Analysis; Hemodynamics; Hypertension, Pulmonary; Lung; Monocrotaline; Nitric Acid; Pulmonary Artery; Regional Blood Flow; Ventricular Function, Left | 1997 |
Single lung transplantation for canine pulmonary hypertension.
Topics: Animals; Cardiopulmonary Bypass; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Pulmonary; Lung Transplantation; Monocrotaline; Organ Size; Pulmonary Circulation; Reproducibility of Results | 1997 |
An adult canine model of chronic pulmonary hypertension for cardiopulmonary transplantation.
Topics: Age Factors; Animals; Catheterization, Swan-Ganz; Chronic Disease; Disease Models, Animal; Dogs; Heart-Lung Transplantation; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Reproducibility of Results; Ventricular Function | 1997 |
Hemodynamic and inotropic effects of nitric oxide in pulmonary hypertension.
Topics: Animals; Body Weight; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Myocardial Contraction; Nitric Oxide; Pulmonary Circulation; Regional Blood Flow; Vascular Resistance | 1997 |
Bioactivation of monocrotaline by P-450 3A in rat liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Heart; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Immunoglobulin G; Liver; Male; Microsomes, Liver; Monocrotaline; Orchiectomy; Organ Size; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Sex Factors; Ventricular Pressure | 1997 |
Pulmonary vascular impedance and recipient chronic pulmonary hypertension following cardiac transplantation.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Electric Impedance; Fourier Analysis; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Poisons; Prospective Studies; Pulmonary Artery | 1997 |
Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension.
Topics: Animals; Dogs; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Milrinone; Monocrotaline; Myocardial Contraction; Phosphodiesterase Inhibitors; Pulmonary Circulation; Pyridones; Ventricular Dysfunction, Right; Ventricular Function, Right | 1998 |
Molecular and functional mechanisms of right ventricular adaptation in chronic pulmonary hypertension.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Chronic Disease; Dogs; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Myocardium; Pulmonary Circulation; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stroke Volume; Ventricular Function, Right | 1999 |
Fibrin thrombosis in monocrotaline pyrrole-induced cor pulmonale in rats.
Topics: Animals; Cardiomegaly; Endothelium; Fibrin; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pulmonary Embolism; Pulmonary Heart Disease; Pyrroles; Pyrrolizidine Alkaloids; Rats | 1977 |
Development of morphologic, hemodynamic, and biochemical changes in lungs of rats given monocrotaline pyrrole.
Topics: Animals; Biomarkers; Body Weight; Bronchoalveolar Lavage Fluid; Dimethylformamide; Hemodynamics; Hypertension, Pulmonary; Injections, Intravenous; L-Lactate Dehydrogenase; Lung; Male; Monocrotaline; Organ Size; Proteins; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Effects of altered platelet number on pulmonary hypertension and platelet sequestration in monocrotaline pyrrole-treated rats.
Topics: Animals; Blood Platelets; Body Weight; Dimethylformamide; Hemoglobins; Hypertension, Pulmonary; Indium Radioisotopes; Injections, Intravenous; Lung; Male; Monocrotaline; Platelet Count; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Splenectomy | 1989 |
Arachidonic acid metabolites and the mechanisms of monocrotaline pneumotoxicity.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Hypertension, Pulmonary; Leukotriene B4; Lung; Monocrotaline; Pyrrolizidine Alkaloids; Rats; SRS-A; Thromboxane A2 | 1987 |
Thromboxane does not mediate pulmonary vascular response to monocrotaline pyrrole.
Topics: Animals; Cyclooxygenase Inhibitors; Dibenzothiepins; Hypertension, Pulmonary; Ibuprofen; Imidazoles; Male; Monocrotaline; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane-A Synthase; Thromboxanes | 1987 |
Pulmonary platelet sequestration is increased following monocrotaline pyrrole treatment of rats.
Topics: Animals; Blood Platelets; Cardiomegaly; Cell Survival; Hemoglobins; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344 | 1988 |
Altered pulmonary vascular smooth muscle responsiveness in monocrotaline-induced pulmonary hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Isoproterenol; Male; Monocrotaline; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Pulmonary Artery; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Vasoconstriction | 1986 |
Pulmonary hypertension due to monocrotaline pyrrole is reduced by moderate thrombocytopenia.
Topics: Animals; Blood Platelets; Blood Pressure; Hypertension, Pulmonary; Immunization, Passive; L-Lactate Dehydrogenase; Male; Monocrotaline; Platelet-Derived Growth Factor; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Thrombocytopenia | 1988 |
6-Ketoprostaglandin F1 alpha and thromboxane B2 in isolated, blood-perfused lungs from monocrotaline pyrrole-treated rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Thromboxane B2 | 1988 |
Complement is not involved in monocrotaline pyrrole-induced pulmonary injury.
Topics: Animals; Complement Activation; Dimethylformamide; Elapid Venoms; Hemolysis; Hypertension, Pulmonary; Isoenzymes; L-Lactate Dehydrogenase; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1988 |
5-Hydroxytryptamine and thromboxane in platelets from rats treated with monocrotaline pyrrole.
Topics: Animals; Blood Platelets; Hypertension, Pulmonary; Male; Monocrotaline; Platelet Aggregation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin; Thromboxane B2; Thromboxanes; Time Factors | 1987 |
The effect of immunosuppressants and adoptive transfer in monocrotaline pyrrole pneumotoxicity.
Topics: Animals; Antilymphocyte Serum; Body Weight; Bronchoalveolar Lavage Fluid; Cyclosporins; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy; Immunization, Passive; Immunosuppressive Agents; L-Lactate Dehydrogenase; Lung; Lymphocytes; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1987 |
Elevated serum copper concentration in monocrotaline pyrrole treated rats with pulmonary hypertension.
Topics: Animals; Copper; Hypertension, Pulmonary; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1987 |
Increased vascular responsiveness in lungs of rats with pulmonary hypertension induced by monocrotaline pyrrole.
Topics: Angiotensin II; Animals; Blood Vessels; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Male; Monocrotaline; Perfusion; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin | 1985 |