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monocrotaline pyrrole and Hypertension, Pulmonary

monocrotaline pyrrole has been researched along with Hypertension, Pulmonary in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199018 (30.51)18.7374
1990's21 (35.59)18.2507
2000's8 (13.56)29.6817
2010's9 (15.25)24.3611
2020's3 (5.08)2.80

Authors

AuthorsStudies
Gu, L; Liu, CJ; Liu, HM; Xie, L; Yu, L1
Dong, J; Jiang, P; Jiang, XM; Li, L; Li, M; Luo, J; Ran, H; Xie, DJ; Zhang, PY; Zhou, L1
Bu, D; Chen, S; Du, J; Huang, Y; Jin, H; Kong, W; Liu, X; Tang, C; Tang, X; Tao, Y; Wang, X; Yang, G; Yu, W; Zhang, D; Zhang, H1
Chen, S; Jiang, X; Li, L; Luo, J; Wang, J; Zhang, J; Zhou, L1
Liu, WH; Liu, ZH; Luo, Q; Wang, Y; Xi, QY; Xu, XH; Zhang, HL; Zhao, ZH1
Dupuis, J; Fang, J; Hu, Q; Jing, ZC; Li, J; Lu, Y; Luo, S; Su, Y; Wang, T; Xiao, R; Zhang, J; Zhu, L1
Cheng, G; Lu, Y; Luan, Y; Zhang, Z1
Berry, GJ; Kao, PN; Nishimura, T; Pearl, RG; Qiao, L; Sessions, D; Shi, L; Thrasher, A; Trudell, JR1
Congxin, H; Qingyan, Z; Shengbo, Y; Wei, H; Xiaozhan, W; Xuejun, J; Xule, W; Yanhong, T; Zixuan, D; Zongwen, G1
Dai, Z; Guo, Z; Hu, W; Huang, C; Jiang, X; Tang, Y; Wang, X; Yang, B; Yu, S; Zhang, S; Zhao, Q1
Chen, JZ; Hu, XS; Liu, SK; Ma, CY; Wang, XX; Xia, L; Zeng, CL1
Dony, E; Dumitrascu, R; Ghofrani, HA; Grimminger, F; Koebrich, S; Pullamsetti, SS; Samidurai, A; Savai, R; Schermuly, RT; Seeger, W; Traupe, H; Weissmann, N1
Chen, JZ; Fu, GS; Qiu, FY; Wang, XX; Xia, L; Xie, XD; Yang, Y; Zhu, JH1
Lu, Y; Luan, Y; Wang, YB; Wei, DE; Zhang, ZH1
Chen, D; Chen, F; Dong, L; Ge, J; Guan, L; Qian, J; Zhou, D1
Austin, DJ; Elefteriades, JA; Goldstein, L; Keane, J; Kopf, GS; Lovoulos, C; Rocco, E; Singh, S; Tang, P; Tittle, S1
Gewitz, M; Huang, J; Mathew, R; Patel, K; Sehgal, PB; Shah, M1
Adnot, S; Barlier-Mur, AM; Eddahibi, S; Guignabert, C; Hamon, M; Hanoun, N; Izikki, M; Li, Z; Rodman, D; Tu, LI; Zadigue, P1
Adnot, S; Eddahibi, S; Giraudier, S; Hulin, A; Maitre, B; Marcos, E; Raoul, W; Saber, G; Vainchenker, W; Wagner-Ballon, O1
Mukhopadhyay, S; Patel, K; Sehgal, PB; Shah, M; Tuder, RM; Xu, F1
Bruner, LH; Hilliker, KS; Roth, RA1
Bell, TG; Deyo, JA; Hilliker, KS; Roth, RA1
Gamble, W; Meyrick, B; Reid, L1
Bell, TG; Hilliker, KS; Roth, RA1
Bell, TG; Hilliker, KS; Lorimer, D; Roth, RA1
Okada, K; Okada, M; Yamashita, C4
Pan, LC; Segall, HJ; Wilson, DW1
Emeis, JJ; Roth, RA; Schultze, AE1
Ito, O; Kasukawa, R; Koike, H; Miyata, M; Nishimaki, T; Nishio, S; Sakuma, F; Sekine, H; Ueno, Y1
Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P5
Bittner, HB; Chen, EP; Craig, DM; Davis, RD; Van Trigt, P1
Bittner, HB; Chen, EP; Craig, D; Davis, RD; Tull, F; Van Trigt, P1
Nohara, H; Okada, K; Okada, M; Wakiyama, H; Yamagishi, H; Yamashita, C1
Biswas, SS; Bittner, HB; Chen, EP; Davis, RD; Tull, F; Van Trigt, P1
Kakusaka, I; Kasahara, Y; Kitada, M; Kiyatake, K; Kuriyama, T; Ohmori, S; Sugito, K; Tatsumi, K; Yamagata, S1
Akhter, SA; Bittner, HB; Chen, EP; Davis, RD; Koch, WJ; Van Trigt, P1
Johnson, WD; Lalich, JL; Raczniak, TJ; Shumaker, RC1
Reindel, JF; Roth, RA1
Ganey, PE; Reindel, JF; Roth, RA; Slocombe, RF; Wagner, JG1
Roth, RA; Wagner, JG; White, SM1
Ganey, PE; Roth, RA5
Roth, RA; White, SM1
Altiere, RJ; Gillespie, MN; Olson, JW1
Ganey, PE; Roth, RA; Sprugel, KH; Wagner, JG; White, SM1
Bruner, LH; Johnson, KJ; Roth, RA; Till, GO1
Bruner, LH; Bull, RW; Roth, RA1
Hilliker, KS; Roth, RA1

Reviews

1 review(s) available for monocrotaline pyrrole and Hypertension, Pulmonary

ArticleYear
Lung vascular injury from monocrotaline pyrrole, a putative hepatic metabolite.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Biotransformation; Endothelium, Vascular; Hypertension, Pulmonary; Liver; Lung; Monocrotaline; Pyrrolizidine Alkaloids

1991

Other Studies

58 other study(ies) available for monocrotaline pyrrole and Hypertension, Pulmonary

ArticleYear
[Pulmonary Vascular Remodeling Characteristics of Pulmonary Arterial Hypertension Mouse Model Induced by Left Pneumonectomy and Jugular Vein Injection of Monocrotaline Pyrrole].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2022, Volume: 53, Issue:5

    Topics: Animals; Disease Models, Animal; Hypertension, Pulmonary; Jugular Veins; Male; Mice; Mice, Inbred C57BL; Monocrotaline; Neointima; Pneumonectomy; Pulmonary Arterial Hypertension; Pulmonary Artery; Vascular Remodeling

2022
Establishment of a canine model of pulmonary arterial hypertension induced by dehydromonocrotaline and ultrasonographic study of right ventricular remodeling.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2023, Dec-31, Volume: 45, Issue:1

    Topics: Animals; Dimethylformamide; Dogs; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Pulmonary Arterial Hypertension; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

2023
Endogenous hydrogen sulfide sulfhydrates IKKβ at cysteine 179 to control pulmonary artery endothelial cell inflammation.
    Clinical science (London, England : 1979), 2019, 10-30, Volume: 133, Issue:20

    Topics: Animals; Cells, Cultured; Cysteine; Cytokines; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Humans; Hydrogen Sulfide; Hypertension, Pulmonary; I-kappa B Kinase; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Male; Monocrotaline; NF-kappa B; Pulmonary Artery; Rats, Wistar; Signal Transduction

2019
Sympathetic innervation of canine pulmonary artery and morphometric and functional analysis in dehydromonocrotaline-induced models after pulmonary artery denervation.
    Interactive cardiovascular and thoracic surgery, 2020, 11-01, Volume: 31, Issue:5

    Topics: Animals; Disease Models, Animal; Dogs; Hypertension, Pulmonary; Lung; Monocrotaline; Pulmonary Artery; Sympathectomy; Sympathetic Nervous System; Vascular Resistance

2020
Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:3

    Topics: Animals; Blood Pressure; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Mevalonic Acid; Monocrotaline; Polyisoprenyl Phosphates; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Signal Transduction; Simvastatin; Vascular Remodeling

2018
Monocrotaline pyrrole induces pulmonary endothelial damage through binding to and release from erythrocytes in lung during venous blood reoxygenation.
    American journal of physiology. Lung cellular and molecular physiology, 2019, 05-01, Volume: 316, Issue:5

    Topics: Animals; Endothelial Cells; Endothelium; Erythrocytes; Hypertension, Pulmonary; Lung; Monocrotaline; Oxygen; Rats; Rats, Sprague-Dawley

2019
[Research on effects of bone marrow mononuclear cells implantation on model of experimental pulmonary artery hypertension].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2013, Volume: 30, Issue:3

    Topics: Animals; Bone Marrow Cells; Cell Transplantation; Dogs; Familial Primary Pulmonary Hypertension; Female; Hypertension, Pulmonary; Leukocytes, Mononuclear; Male; Monocrotaline; Rats

2013
Endothelial fate mapping in mice with pulmonary hypertension.
    Circulation, 2014, Feb-11, Volume: 129, Issue:6

    Topics: Actins; Alkylating Agents; Animals; Antigens, CD; Cadherins; Cell Lineage; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Humans; Hypertension, Pulmonary; Integrases; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monocrotaline; Neointima; Pneumonectomy; Pulmonary Artery; von Willebrand Factor

2014
Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension.
    Revista espanola de cardiologia (English ed.), 2015, Volume: 68, Issue:7

    Topics: Angiotensin II; Animals; Collagen; Dimethylformamide; Dinoprostone; Dogs; Echocardiography; Electrocardiography; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Kidney; Lung; Male; Monocrotaline; Neurotransmitter Agents; Random Allocation; Renal Artery; Renin-Angiotensin System; Sympathectomy; Vascular Remodeling

2015
[Beneficial effects of renal denervation on pulmonary vascular remodeling in experimental pulmonary artery hypertension].
    Zhonghua yi xue za zhi, 2015, Apr-14, Volume: 95, Issue:14

    Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dogs; Echocardiography; Endothelin-1; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Kidney; Lung; Monocrotaline; Pulmonary Artery; Sympathectomy; Vascular Remodeling

2015
[Quantitative and functional changes of circulating endothelial progenitor cells in dogs with dehydromonocrotaline-induced pulmonary artery hypertension].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2008, Volume: 31, Issue:5

    Topics: Animals; Cell Count; Cells, Cultured; Disease Models, Animal; Dogs; Endothelial Cells; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Stem Cells

2008
Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury.
    BMC pulmonary medicine, 2008, Dec-17, Volume: 8

    Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Injections, Subcutaneous; Lung; Lung Compliance; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Monocrotaline; Neutrophils; Rats; Rats, Sprague-Dawley; Survival Rate

2008
Senescent endothelial progenitor cells from dogs with pulmonary arterial hypertension: a before-after self-controlled study.
    The journal of physiological sciences : JPS, 2009, Volume: 59, Issue:6

    Topics: Animals; Cell Culture Techniques; Cell Separation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Dogs; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Hypertension, Pulmonary; Male; Monocrotaline; Neovascularization, Physiologic; Stem Cells

2009
Effects of autologous bone marrow mononuclear cells implantation in canine model of pulmonary hypertension.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:4

    Topics: Animals; Bone Marrow Transplantation; Cell Differentiation; Cell Separation; Cell Tracking; Disease Models, Animal; Dogs; Endothelial Cells; Endothelin-1; Flow Cytometry; Fluorescent Antibody Technique; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-6; Monocrotaline; Neovascularization, Physiologic; Pulmonary Artery; RNA, Messenger; Stem Cell Transplantation; Time Factors; Transplantation, Autologous; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Ventricular Function, Right

2012
Atorvastatin prevents dehydromonocrotaline-induced pulmonary hypertension in beagles.
    Experimental lung research, 2012, Volume: 38, Issue:7

    Topics: Alkylating Agents; Animals; Atorvastatin; Cell Proliferation; Cytokines; Dogs; Endothelium, Vascular; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Pyrroles

2012
Right ventricle-sparing heart transplantation effective against iatrogenic pulmonary hypertension.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004, Volume: 23, Issue:2

    Topics: Alkylating Agents; Animals; Dogs; Heart Transplantation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Iatrogenic Disease; Monocrotaline

2004
Disruption of endothelial-cell caveolin-1alpha/raft scaffolding during development of monocrotaline-induced pulmonary hypertension.
    Circulation, 2004, Sep-14, Volume: 110, Issue:11

    Topics: Animals; Caveolin 1; Caveolins; Disease Models, Animal; DNA-Binding Proteins; Endothelial Cells; Endothelium, Vascular; Heat-Shock Proteins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isomerases; Male; Membrane Microdomains; Mitosis; Monocrotaline; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Pulmonary Artery; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Trans-Activators; von Willebrand Factor

2004
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.
    Circulation research, 2006, May-26, Volume: 98, Issue:10

    Topics: Acute Disease; Animals; Blood Pressure; Blood Vessels; Humans; Hydroxyindoleacetic Acid; Hypertension, Pulmonary; Hypoxia; Lung; Mice; Mice, Transgenic; Monocrotaline; Muscle, Smooth, Vascular; Pulmonary Artery; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution; Transgenes; Vasoconstriction; Ventricular Function, Right

2006
Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice.
    Respiratory research, 2007, Jan-30, Volume: 8

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Disease Models, Animal; Female; Green Fluorescent Proteins; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monocrotaline; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Artery; Stem Cell Transplantation; Stem Cells; Time Factors; Ventricular Function, Right; Ventricular Pressure

2007
Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 294, Issue:3

    Topics: Animals; Cattle; Caveolin 1; Cell Compartmentation; Cells, Cultured; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Lysosomes; Male; Monocrotaline; Muscle, Smooth, Vascular; Protein Disulfide-Isomerases; Protein Transport; Rats; STAT3 Transcription Factor

2008
Pulmonary hypertension and ECG changes from monocrotaline pyrrole in the rat.
    The American journal of physiology, 1983, Volume: 245, Issue:2

    Topics: Animals; Blood Cell Count; Body Weight; Cardiomegaly; Electrocardiography; Heart; Heart Ventricles; Hypertension, Pulmonary; Kinetics; Lung; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

1983
Aggregation of platelets from monocrotaline pyrrole-treated rats.
    Thrombosis research, 1983, Nov-01, Volume: 32, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Hypertension, Pulmonary; Male; Monocrotaline; Platelet Aggregation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Time Factors

1983
Development of Crotalaria pulmonary hypertension: hemodynamic and structural study.
    The American journal of physiology, 1980, Volume: 239, Issue:5

    Topics: Animals; Blood Gas Analysis; Body Temperature; Cardiomegaly; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Pyrroles; Pyrrolizidine Alkaloids; Rats

1980
Monocrotaline pyrrole-induced pulmonary hypertension in fawn-hooded rats with platelet storage pool deficiency: 5-hydroxytryptamine uptake by isolated, perfused lungs.
    Thrombosis and haemostasis, 1983, Dec-30, Volume: 50, Issue:4

    Topics: Animals; Blood Cell Count; Blood Platelets; Heart; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Organ Size; Perfusion; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin

1983
Effects of thrombocytopenia on monocrotaline pyrrole-induced pulmonary hypertension.
    The American journal of physiology, 1984, Volume: 246, Issue:6 Pt 2

    Topics: Animals; Blood Platelets; Body Weight; Hypertension, Pulmonary; Immune Sera; Lung; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Thrombocytosis

1984
[Pulmonary lobe transplantation in pulmonary hypertensive dogs under cardiopulmonary bypass].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1995, Volume: 43, Issue:5

    Topics: Animals; Cardiopulmonary Bypass; Dogs; Hypertension, Pulmonary; Lung Transplantation; Monocrotaline

1995
Establishment of canine pulmonary hypertension with dehydromonocrotaline. Importance of larger animal model for lung transplantation.
    Transplantation, 1995, Jul-15, Volume: 60, Issue:1

    Topics: Animals; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Pulmonary; Lung Transplantation; Monocrotaline; Pulmonary Artery; Rats

1995
A dehydromonocrotaline-induced pulmonary hypertension model in the beagle.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:2

    Topics: Animals; Disease Models, Animal; Dogs; Hypertension, Pulmonary; Monocrotaline

1995
Role of endothelin-1 in beagles with dehydromonocrotaline-induced pulmonary hypertension.
    Circulation, 1995, Jul-01, Volume: 92, Issue:1

    Topics: Animals; Azepines; Dogs; Endothelins; Hemodynamics; Hypertension, Pulmonary; Indoles; Monocrotaline; Peptides, Cyclic; Viper Venoms

1995
Endothelin receptor antagonists in a beagle model of pulmonary hypertension: contribution to possible potential therapy?
    Journal of the American College of Cardiology, 1995, Volume: 25, Issue:5

    Topics: Alprostadil; Animals; Azepines; Dogs; Endothelin Receptor Antagonists; Hemodynamics; Hypertension, Pulmonary; Indoles; Monocrotaline; Nitroglycerin; Peptides, Cyclic; Pulmonary Circulation

1995
Strain differences in the response of Fischer 344 and Sprague-Dawley rats to monocrotaline induced pulmonary vascular disease.
    Toxicology, 1993, Mar-30, Volume: 79, Issue:1

    Topics: Animals; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Species Specificity; Weight Gain

1993
Cellular fibronectin and von Willebrand factor concentrations in plasma of rats treated with monocrotaline pyrrole.
    Biochemical pharmacology, 1996, Jan-26, Volume: 51, Issue:2

    Topics: Animals; Endothelium, Vascular; Fibronectins; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Time Factors; von Willebrand Factor

1996
Protective effect of beraprost sodium, a stable prostacyclin analogue, in development of monocrotaline-induced pulmonary hypertension.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:1

    Topics: Alprostadil; Animals; Endothelium, Vascular; Epoprostenol; Hypertension, Pulmonary; Interleukin-1; Interleukin-6; Male; Mice; Monocrotaline; Platelet Aggregation Inhibitors; Poisons; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vasodilator Agents

1996
Right ventricular failure--insights provided by a new model of chronic pulmonary hypertension.
    Transplantation, 1997, Jan-27, Volume: 63, Issue:2

    Topics: Administration, Inhalation; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Infusions, Intravenous; Milrinone; Monocrotaline; Nitric Oxide; Pulmonary Artery; Pyridones; Vascular Resistance; Vasodilator Agents; Ventricular Dysfunction, Right; Ventricular Function, Right

1997
Pulmonary hemodynamics and blood flow characteristics in chronic pulmonary hypertension.
    The Annals of thoracic surgery, 1997, Volume: 63, Issue:3

    Topics: Animals; Blood Flow Velocity; Chronic Disease; Disease Models, Animal; Dogs; Fourier Analysis; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Pulmonary Wedge Pressure; Signal Processing, Computer-Assisted; Ultrasonography; Vascular Resistance

1997
Milrinone improves pulmonary hemodynamics and right ventricular function in chronic pulmonary hypertension.
    The Annals of thoracic surgery, 1997, Volume: 63, Issue:3

    Topics: Animals; Cardiotonic Agents; Chronic Disease; Dogs; Fourier Analysis; Hypertension, Pulmonary; Milrinone; Monocrotaline; Pulmonary Circulation; Pulmonary Wedge Pressure; Pyridones; Signal Processing, Computer-Assisted; Ultrasonography; Vascular Resistance; Vasodilator Agents; Ventricular Function, Right

1997
Nitric oxide improves pulmonary vascular impedance, transpulmonary efficiency, and left ventricular filling in chronic pulmonary hypertension.
    The Journal of thoracic and cardiovascular surgery, 1997, Volume: 113, Issue:5

    Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Fourier Analysis; Hemodynamics; Hypertension, Pulmonary; Lung; Monocrotaline; Nitric Acid; Pulmonary Artery; Regional Blood Flow; Ventricular Function, Left

1997
Single lung transplantation for canine pulmonary hypertension.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1997, Volume: 16, Issue:5

    Topics: Animals; Cardiopulmonary Bypass; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Pulmonary; Lung Transplantation; Monocrotaline; Organ Size; Pulmonary Circulation; Reproducibility of Results

1997
An adult canine model of chronic pulmonary hypertension for cardiopulmonary transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1997, Volume: 16, Issue:5

    Topics: Age Factors; Animals; Catheterization, Swan-Ganz; Chronic Disease; Disease Models, Animal; Dogs; Heart-Lung Transplantation; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Reproducibility of Results; Ventricular Function

1997
Hemodynamic and inotropic effects of nitric oxide in pulmonary hypertension.
    The Journal of surgical research, 1997, Volume: 69, Issue:2

    Topics: Animals; Body Weight; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Myocardial Contraction; Nitric Oxide; Pulmonary Circulation; Regional Blood Flow; Vascular Resistance

1997
Bioactivation of monocrotaline by P-450 3A in rat liver.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Heart; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Immunoglobulin G; Liver; Male; Microsomes, Liver; Monocrotaline; Orchiectomy; Organ Size; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Sex Factors; Ventricular Pressure

1997
Pulmonary vascular impedance and recipient chronic pulmonary hypertension following cardiac transplantation.
    Chest, 1997, Volume: 112, Issue:6

    Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Electric Impedance; Fourier Analysis; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Poisons; Prospective Studies; Pulmonary Artery

1997
Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1998, Volume: 17, Issue:7

    Topics: Animals; Dogs; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Milrinone; Monocrotaline; Myocardial Contraction; Phosphodiesterase Inhibitors; Pulmonary Circulation; Pyridones; Ventricular Dysfunction, Right; Ventricular Function, Right

1998
Molecular and functional mechanisms of right ventricular adaptation in chronic pulmonary hypertension.
    The Annals of thoracic surgery, 1999, Volume: 67, Issue:4

    Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Chronic Disease; Dogs; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Myocardium; Pulmonary Circulation; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stroke Volume; Ventricular Function, Right

1999
Fibrin thrombosis in monocrotaline pyrrole-induced cor pulmonale in rats.
    Archives of pathology & laboratory medicine, 1977, Volume: 101, Issue:2

    Topics: Animals; Cardiomegaly; Endothelium; Fibrin; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pulmonary Embolism; Pulmonary Heart Disease; Pyrroles; Pyrrolizidine Alkaloids; Rats

1977
Development of morphologic, hemodynamic, and biochemical changes in lungs of rats given monocrotaline pyrrole.
    Toxicology and applied pharmacology, 1990, Volume: 106, Issue:2

    Topics: Animals; Biomarkers; Body Weight; Bronchoalveolar Lavage Fluid; Dimethylformamide; Hemodynamics; Hypertension, Pulmonary; Injections, Intravenous; L-Lactate Dehydrogenase; Lung; Male; Monocrotaline; Organ Size; Proteins; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Time Factors

1990
Effects of altered platelet number on pulmonary hypertension and platelet sequestration in monocrotaline pyrrole-treated rats.
    Toxicology and applied pharmacology, 1989, Jun-15, Volume: 99, Issue:2

    Topics: Animals; Blood Platelets; Body Weight; Dimethylformamide; Hemoglobins; Hypertension, Pulmonary; Indium Radioisotopes; Injections, Intravenous; Lung; Male; Monocrotaline; Platelet Count; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Splenectomy

1989
Arachidonic acid metabolites and the mechanisms of monocrotaline pneumotoxicity.
    The American review of respiratory disease, 1987, Volume: 136, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Hypertension, Pulmonary; Leukotriene B4; Lung; Monocrotaline; Pyrrolizidine Alkaloids; Rats; SRS-A; Thromboxane A2

1987
Thromboxane does not mediate pulmonary vascular response to monocrotaline pyrrole.
    The American journal of physiology, 1987, Volume: 252, Issue:4 Pt 2

    Topics: Animals; Cyclooxygenase Inhibitors; Dibenzothiepins; Hypertension, Pulmonary; Ibuprofen; Imidazoles; Male; Monocrotaline; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane-A Synthase; Thromboxanes

1987
Pulmonary platelet sequestration is increased following monocrotaline pyrrole treatment of rats.
    Toxicology and applied pharmacology, 1988, Volume: 96, Issue:3

    Topics: Animals; Blood Platelets; Cardiomegaly; Cell Survival; Hemoglobins; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344

1988
Altered pulmonary vascular smooth muscle responsiveness in monocrotaline-induced pulmonary hypertension.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:2

    Topics: Acetylcholine; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Isoproterenol; Male; Monocrotaline; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Pulmonary Artery; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Vasoconstriction

1986
Pulmonary hypertension due to monocrotaline pyrrole is reduced by moderate thrombocytopenia.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Animals; Blood Platelets; Blood Pressure; Hypertension, Pulmonary; Immunization, Passive; L-Lactate Dehydrogenase; Male; Monocrotaline; Platelet-Derived Growth Factor; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Thrombocytopenia

1988
6-Ketoprostaglandin F1 alpha and thromboxane B2 in isolated, blood-perfused lungs from monocrotaline pyrrole-treated rats.
    Journal of toxicology and environmental health, 1988, Volume: 23, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Thromboxane B2

1988
Complement is not involved in monocrotaline pyrrole-induced pulmonary injury.
    The American journal of physiology, 1988, Volume: 254, Issue:2 Pt 2

    Topics: Animals; Complement Activation; Dimethylformamide; Elapid Venoms; Hemolysis; Hypertension, Pulmonary; Isoenzymes; L-Lactate Dehydrogenase; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

1988
5-Hydroxytryptamine and thromboxane in platelets from rats treated with monocrotaline pyrrole.
    Toxicology and applied pharmacology, 1987, Volume: 88, Issue:2

    Topics: Animals; Blood Platelets; Hypertension, Pulmonary; Male; Monocrotaline; Platelet Aggregation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin; Thromboxane B2; Thromboxanes; Time Factors

1987
The effect of immunosuppressants and adoptive transfer in monocrotaline pyrrole pneumotoxicity.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:1

    Topics: Animals; Antilymphocyte Serum; Body Weight; Bronchoalveolar Lavage Fluid; Cyclosporins; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy; Immunization, Passive; Immunosuppressive Agents; L-Lactate Dehydrogenase; Lung; Lymphocytes; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Inbred Strains

1987
Elevated serum copper concentration in monocrotaline pyrrole treated rats with pulmonary hypertension.
    Biochemical pharmacology, 1987, Oct-15, Volume: 36, Issue:20

    Topics: Animals; Copper; Hypertension, Pulmonary; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

1987
Increased vascular responsiveness in lungs of rats with pulmonary hypertension induced by monocrotaline pyrrole.
    The American review of respiratory disease, 1985, Volume: 131, Issue:1

    Topics: Angiotensin II; Animals; Blood Vessels; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Male; Monocrotaline; Perfusion; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin

1985
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