monocrotaline and Right Ventricular Dysfunction

Topics: Animals; Disease Models, Animal; Heart Failure; Humans; Hypertension, Pulmonary; Monocrotaline; Pulmonary Artery; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Calcium; Connexin 43; Disease Models, Animal; Fura-2; Glucose; Glucosides; Heart Failure; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Sodium; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Hemoglobins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Inositol Phosphates; Male; Monocrotaline; Myocardial Contraction; Rats; Rats, Wistar; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Apoptosis; Arterial Pressure; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor CHOP; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; X-Box Binding Protein 1

Topics: Animals; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fasting; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Pulmonary Arterial Hypertension; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Anticholesteremic Agents; Antioxidants; Catalase; Echocardiography; Glutathione Peroxidase; Heart; Heart Failure; Hemodynamics; Hypertension, Pulmonary; Lipid Peroxidation; Lovastatin; Lung; Monocrotaline; Myocardium; Organ Size; Oxidative Stress; Probucol; Rats; Superoxide Dismutase; Ventricular Dysfunction, Right

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Pulmonary Artery; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, G-Protein-Coupled; Receptors, Neurotransmitter; Systole; Vasoconstriction; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Arrhythmias, Cardiac; Dantrolene; Disease Models, Animal; Hypertension, Pulmonary; Male; Monocrotaline; Prognosis; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Fluvoxamine; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Atrial Natriuretic Factor; Cytokine Receptor gp130; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fibrosis; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammasomes; Macrophage Activation; Macrophages; Monocrotaline; NLR Family, Pyrin Domain-Containing 3 Protein; Pulmonary Arterial Hypertension; Rats; Ventricular Dysfunction, Right

Topics: Animals; Disease Models, Animal; Echocardiography; Heart Ventricles; Hypertension, Pulmonary; Monocrotaline; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Acylation; Adult; Aged; AMP-Activated Protein Kinases; Animals; Cell Line; Cohort Studies; Colchicine; Diabetes Mellitus; Disease Models, Animal; Echocardiography; Gene Expression Regulation; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hexosamines; Humans; Hypertrophy, Right Ventricular; Male; Metabolome; Middle Aged; Mitochondria; Monocrotaline; Myocytes, Cardiac; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right

Topics: Animals; Antihypertensive Agents; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Monocrotaline; Predictive Value of Tests; Pulmonary Arterial Hypertension; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Synchrotrons; Vasodilation; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Animals; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Heart Failure; Heart Ventricles; Humans; Hypoxia; Indoles; Male; Middle Aged; Monocrotaline; Pulmonary Arterial Hypertension; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; RNA-Seq; Transcriptome; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Arterioles; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Signal Transduction; Soluble Guanylyl Cyclase; Styrenes; Vascular Remodeling; Vasodilation; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Butylene Glycols; Cardiomegaly; Glucosides; Male; Monocrotaline; Oxidative Stress; Rats; Rats, Wistar; Ventricular Dysfunction, Right

Topics: Animals; Autophagy; Beclin-1; Hypertension, Pulmonary; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Hemodynamics; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Rats, Wistar; Receptors, Adrenergic, beta-2; Signal Transduction; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Antimycin A; Electron Transport Complex III; Female; Glycolysis; Humans; Hypertension, Pulmonary; Lung; Male; Mitochondria; Monocrotaline; Rats; Rats, Sprague-Dawley; Vasoconstriction; Ventricular Dysfunction, Right

Topics: Animals; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling; Ventricular Dysfunction, Right

Topics: Animals; Computational Biology; Databases, Genetic; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Lipopolysaccharides; Male; Monocrotaline; Rats, Sprague-Dawley; RNA, Long Noncoding; RNA, Messenger; Transcriptome; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cardiovascular Agents; Disease Models, Animal; Fabaceae; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; JNK Mitogen-Activated Protein Kinases; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Oils; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Signal Transduction; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Arterial Pressure; Beta vulgaris; Dietary Supplements; Disease Models, Animal; Fruit and Vegetable Juices; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide; Plant Roots; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Biomarkers; Disease Models, Animal; Echocardiography; Estradiol; Fibrosis; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Natriuretic Peptide, Brain; Rats, Sprague-Dawley; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

Topics: Adrenergic beta-Antagonists; Animals; Creatine Kinase; Disease Models, Animal; Energy Metabolism; Enzyme Activation; Heart Failure; Hypertension, Pulmonary; Hypoxia; Male; Mitochondria; Monocrotaline; Muscle Cells; Oxygen; Rats; Ventricular Dysfunction, Right

Topics: Animals; Antihypertensive Agents; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Female; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Phenylpropionates; Pneumonectomy; Pulmonary Artery; Pyridazines; Rats; Rats, Sprague-Dawley; Tadalafil; Vascular Remodeling; Vasoconstriction; Ventricular Dysfunction, Right; X-Ray Microtomography

Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Collagen Type I; Connexin 43; Death, Sudden, Cardiac; Drug Therapy, Combination; Epoprostenol; Gene Expression Regulation; Heart; Humans; Hypertension, Pulmonary; Male; Monocrotaline; Organ Culture Techniques; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Ventricular Dysfunction, Right; Ventricular Remodeling; Voltage-Sensitive Dye Imaging

Topics: Animals; Antimicrobial Cationic Peptides; Gene Expression; Hepcidins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Iron, Dietary; Kaplan-Meier Estimate; Lung; Male; Monocrotaline; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; Reverse Transcriptase Polymerase Chain Reaction; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Adaptation, Physiological; Animals; Arteriovenous Shunt, Surgical; Constriction; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Models, Cardiovascular; Monocrotaline; Myocardial Contraction; Physical Exertion; Pulmonary Artery; Rats; Rats, Wistar; Stroke Volume; Time Factors; Ultrasonography; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure

Topics: Animals; Gene Expression Profiling; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hypoxia; Male; Monocrotaline; Proteasome Endopeptidase Complex; Proteolysis; Proteome; Rats; Rats, Wistar; Signal Transduction; Ubiquitination; Ventricular Dysfunction, Right

Topics: Administration, Inhalation; Animals; Becaplermin; Benzimidazoles; Blotting, Western; Cell Proliferation; Cells, Cultured; Hemodynamics; Hypertension, Pulmonary; Large-Conductance Calcium-Activated Potassium Channels; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocrotaline; Myocytes, Smooth Muscle; Oxygen; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right; Ventricular Pressure

Topics: Adult; Aged, 80 and over; Animals; Antihypertensive Agents; Case-Control Studies; Cell Hypoxia; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Enzyme Inhibitors; Familial Primary Pulmonary Hypertension; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Isoenzymes; Male; Mice; Middle Aged; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein-Lysine 6-Oxidase; Pulmonary Artery; Rats; RNA, Messenger; Ventricular Dysfunction, Right; Young Adult

Topics: Animals; Arrhythmias, Cardiac; Elastic Modulus; Excitation Contraction Coupling; Heart Conduction System; Hypertension, Pulmonary; Ion Channel Gating; Ion Channels; Mechanotransduction, Cellular; Monocrotaline; Physical Stimulation; Rats; Rats, Wistar; Stress, Mechanical; Systems Biology; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CCL2; Disease Models, Animal; DNA-Binding Proteins; Endothelin-1; Hemodynamics; HMGB1 Protein; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Interleukin-1beta; Male; Monocrotaline; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vascular Resistance; Ventricular Dysfunction, Right

Topics: Animals; Antihypertensive Agents; Arterial Pressure; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Glycyrrhizic Acid; HMGB1 Protein; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Muscle, Smooth, Vascular; Pneumonia; Pulmonary Artery; Rats, Sprague-Dawley; Time Factors; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Adenosine Triphosphate; Animals; Apoptosis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Isoquinolines; Male; Mitochondria; Mitochondrial Membranes; Monocrotaline; NAD; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-2; Ventricular Dysfunction, Right

Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

Topics: Administration, Inhalation; Animals; Arterial Pressure; Cardiotonic Agents; Disease Models, Animal; Disease Progression; Dobutamine; Energy Metabolism; Heart Failure; Hexokinase; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; L-Lactate Dehydrogenase; Male; Mitochondria, Heart; Monocrotaline; Oxygen; Oxygen Consumption; Protoporphyrins; Pulmonary Artery; Rats, Wistar; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nicorandil; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 5 Inhibitors; Pyridazines; Rats, Wistar; Recovery of Function; Severity of Illness Index; Sildenafil Citrate; Vasodilator Agents; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Antioxidants; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Melatonin; Monocrotaline; Rats; Rats, Long-Evans; Ventricular Dysfunction, Right

Topics: Action Potentials; Age Factors; Animals; Calcium Signaling; Disease Models, Animal; Female; Heart Failure; Heart Ventricles; Isometric Contraction; Male; Monocrotaline; Myocardial Contraction; Rats, Wistar; Sex Factors; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Aerosols; Animals; Carbon Dioxide; Cardiovascular Agents; Disease Models, Animal; Hemodynamics; HSP72 Heat-Shock Proteins; Hypertension, Pulmonary; Male; Monocrotaline; Myocardium; Nebulizers and Vaporizers; Nitric Oxide Synthase Type III; Phosphorylation; Rats, Wistar; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Cytokines; Disease Models, Animal; Exercise Therapy; Male; Monocrotaline; Myocardium; Physical Exertion; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Disease Models, Animal; Echocardiography; Fractals; Heart Failure; Hypertension, Pulmonary; Male; Monocrotaline; Myocytes, Cardiac; Rats, Wistar; Reference Values; Reproducibility of Results; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right

Topics: Animals; Diastole; Elasticity; Hypertension, Pulmonary; Male; Monocrotaline; Multivariate Analysis; Rats; Rats, Wistar; ROC Curve; Stroke Volume; Vascular Stiffness; Ventricular Dysfunction, Right; Ventricular Pressure

Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endothelium, Vascular; Genetic Therapy; Hypertension, Pulmonary; Injections, Spinal; Lung; Mitochondrial Proton-Translocating ATPases; Monocrotaline; Neutrophil Infiltration; Oxidative Phosphorylation Coupling Factors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Vascular Remodeling; Ventricular Dysfunction, Right

Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Case-Control Studies; Disease Models, Animal; Disease Progression; Endothelin-1; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Liver; Lung; Male; Middle Aged; Monocrotaline; Niacinamide; Nicotinamide N-Methyltransferase; Nitric Oxide; Rats, Wistar; Signal Transduction; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Activating Transcription Factor 6; Animals; Apoptosis; eIF-2 Kinase; Endoplasmic Reticulum Stress; Heart Ventricles; Heat-Shock Proteins; Hypertension, Pulmonary; Male; Membrane Proteins; Monocrotaline; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptide Fragments; Phenylbutyrates; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor CHOP; Ventricular Dysfunction, Right

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Captopril; Disease Models, Animal; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Wistar; Ventricular Dysfunction, Right

Topics: Animals; Blood Pressure; Body Weight; Endothelin-1; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Organ Size; Ovariectomy; Pulmonary Artery; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Substrate Specificity; Time Factors; Ventricular Dysfunction, Right

Topics: Animals; Blood Pressure; Gene Expression; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Immunohistochemistry; Integrins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Rats; Rats, Wistar; Tenascin; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling

Topics: Animals; Cardiac Pacing, Artificial; Chronic Disease; Disease Models, Animal; Heart Failure; Heart Septum; Hypertension, Pulmonary; In Vitro Techniques; Magnetic Resonance Imaging; Male; Monocrotaline; Myocardial Contraction; Perfusion; Rats; Reproducibility of Results; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure

Topics: Animals; Arterioles; Cardiac Output; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Extracellular Matrix Proteins; Female; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation Mediators; Lung; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Myocardial Contraction; Myocardium; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Wistar; Recovery of Function; RNA, Messenger; Stroke Volume; Time Factors; Transplantation, Homologous; Vascular Endothelial Growth Factor A; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling

Topics: Animals; Calpain; Dystroglycans; Dystrophin-Associated Protein Complex; Heart Failure; Heart Ventricles; Hemodynamics; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Monocrotaline; Myocardium; Rats; Rats, Wistar; Sarcoglycans; Time Factors; Ventricular Dysfunction, Right

Topics: Animals; Antioxidants; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Organometallic Compounds; Rats; Rats, Wistar; Reactive Oxygen Species; Salicylates; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Autoradiography; Disease Models, Animal; Disease Progression; Gallium Radioisotopes; Gene Expression Profiling; Heart Failure; Hypertrophy, Right Ventricular; Immunochemistry; Inflammation; Male; Monocrotaline; Myocardium; Neutrophil Activation; Peroxidase; Radionuclide Imaging; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Right

Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Body Weight; Fluorobenzenes; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Organ Size; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Signal Transduction; Sulfonamides; Ventricular Dysfunction, Right

Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelin-1; Everolimus; Female; Hypertension, Pulmonary; Monocrotaline; Nitroprusside; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sirolimus; Sulfones; Vasoconstrictor Agents; Vasodilator Agents; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Bone Marrow Cells; Hemodynamics; Hypertension, Pulmonary; Injections, Subcutaneous; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right

Topics: Animals; Calcium; Disease Models, Animal; Excitation Contraction Coupling; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Microscopy, Confocal; Monocrotaline; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Remodeling

Topics: Animals; Calcium; Calcium-Binding Proteins; Disease Models, Animal; Dogs; Heart Ventricles; Monocrotaline; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Dysfunction, Right; Ventricular Pressure

Topics: Animals; Citrate (si)-Synthase; Gene Expression; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Male; Mitochondria, Muscle; Monocrotaline; Muscle, Skeletal; Nuclear Respiratory Factor 1; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Wistar; RNA-Binding Proteins; Sirtuin 1; Transcription Factors; Ventricular Dysfunction, Right

Topics: Animals; Apoptosis; Heart Failure; Monocrotaline; Muscle, Skeletal; Muscular Atrophy; Myosin Heavy Chains; Rats; Rats, Sprague-Dawley; Sphingosine; Thalidomide; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Right

Topics: Animals; Blood Pressure; Cardiac Output; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Male; Monocrotaline; Organ Size; Rats; Rats, Wistar; Stroke Volume; Time Factors; Ventricular Dysfunction, Right; Ventricular Pressure

Topics: Adenoviridae; Animals; Cells, Cultured; Disease Models, Animal; DNA, Complementary; Femoral Vein; Genetic Therapy; Genetic Vectors; Humans; Hypertension, Pulmonary; Injections, Intravenous; Male; Mesenchymal Stem Cell Transplantation; Monocrotaline; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right

Topics: Animals; Disease Models, Animal; Disease Progression; Heart Failure; Male; Monocrotaline; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Ultrasonography; Ventricular Dysfunction, Right

Topics: Animals; Blood Pressure; GATA6 Transcription Factor; Gene Expression Regulation; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ventricular Dysfunction, Right

Topics: Animals; Animals, Genetically Modified; Arterioles; Bone Marrow Cells; Bone Marrow Transplantation; Capillaries; Cell Differentiation; Disease Models, Animal; Femoral Artery; Green Fluorescent Proteins; Hypertension, Pulmonary; Male; Monocrotaline; Pneumonectomy; Pulmonary Artery; Pulmonary Embolism; Rats; Rats, Sprague-Dawley; Thrombosis; Tunica Intima; Ventricular Dysfunction, Right

Topics: Animals; Biomarkers; Biomechanical Phenomena; Electron Transport Complex II; Heart Ventricles; Hypoxia-Inducible Factor 1, alpha Subunit; Luminescence; Male; Membrane Glycoproteins; Microscopy, Fluorescence; Mitochondria, Heart; Monocrotaline; Myocardium; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; rac1 GTP-Binding Protein; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Ubiquinone; Ventricular Dysfunction, Right

Topics: Administration, Inhalation; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Infusions, Intravenous; Milrinone; Monocrotaline; Nitric Oxide; Pulmonary Artery; Pyridones; Vascular Resistance; Vasodilator Agents; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Dogs; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Milrinone; Monocrotaline; Myocardial Contraction; Phosphodiesterase Inhibitors; Pulmonary Circulation; Pyridones; Ventricular Dysfunction, Right; Ventricular Function, Right

Topics: Animals; Anticholesteremic Agents; Blood Pressure; Diet; Disease Progression; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Probucol; Rats; Rats, Wistar; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure