monocrotaline has been researched along with Hypertrophy in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.50) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 7 (29.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Kaisho, M; Okada, M; Otani, K; Sugiyama, A; Yamawaki, H | 1 |
| Huang, Y; Jing, ZC; Li, J; Liu, YW; Meng, J; Pan, HZ; Wang, PH; Xiang, L; Yang, J; Zhang, H; Zhang, XL | 1 |
| Fuji, S; Hiramatsu, Y; Hyodo, K; Kubota, M; Matsushita, S; Miyakawa, K; Osaka, M; Sakamoto, H; Tanioka, K; Tokunaga, C | 1 |
| Dingendorf, A; Dumitrascu, R; Ghofrani, HA; Grimminger, F; Hackemack, S; Kaulen, C; Klepetko, W; Kolosionek, E; Middendorff, R; Mittendorf, J; Müller, D; Pullamsetti, SS; Schermuly, RT; Schlüter, KD; Seeger, W; Stasch, JP; Weissmann, N | 1 |
| Iino, K; Ito, H; Koyama, T; Murakami, M; Ohba, T; Ono, K; Watanabe, H | 1 |
| Jin, M; Li, L; Li, M; Shi, X; Zhang, Y; Zheng, Y | 1 |
| de Man, FS; Handoko, ML; Mouchaers, KT; van der Laarse, WJ; Vonk-Noordegraaf, A; Wong, YY | 1 |
| das Neves, LA; Gralinski, MR; Huang, J; Nikula, KJ; Senese, PB; Zopf, DA | 1 |
| Arons, E; Christou, H; Khalil, RA; Kourembanas, S; Mam, V; Mitsialis, SA; Reslan, OM; Tanbe, AF; Touma, M; Vitali, SH | 1 |
| Han, DD; Liu, JR; Wang, HL; Wang, Y; Zhang, XH | 1 |
| Ermert, L; Ghofrani, HA; Grimminger, F; Kreisselmeier, KP; Pullamsetti, S; Samidurai, A; Schermuly, RT; Schudt, C; Seeger, W; Weissmann, N | 1 |
| Ikeda, U; Ito, T; Kume, A; Mimuro, J; Miyashita, H; Mizukami, H; Okada, T; Ozawa, K; Sakata, Y; Shimada, K; Takahashi, M; Uchibori, R; Urabe, M | 1 |
| Altiere, RJ; Gillespie, MN; Hacker, AD; Olson, JW | 1 |
| Will, JA | 1 |
| Gunaga, KP; Hoorn, CM; Moorehead, WR; Roth, RA; Schultze, AE; Wagner, JG | 1 |
| Harada, Y; Inoue, M; Mori, C; Tanaka, O; Watanabe, K | 1 |
| Kakusaka, I; Kasahara, Y; Kitada, M; Kiyatake, K; Kuriyama, T; Ohmori, S; Sugito, K; Tatsumi, K; Yamagata, S | 1 |
| Bernstein, ML; Botney, MD; Okada, K; Schuster, DP; Zhang, W | 1 |
| Inoue, M; Iwamoto, A; Kanda, T; Kobayashi, I; Nagai, R; Sumino, H; Takahashi, T | 1 |
| Block, N; Brock, TA; Chen, SJ; Chen, YF; Dixon, RA; Munsch, CL; Sherwood, SJ; Tilton, RG; Wu, C | 1 |
| Brodde, OE; Leineweber, K; Seyfarth, T | 1 |
| Dodo, H; Keeley, FW; McCready, L; Rabinovitch, M; Todorovich-Hunter, L; Ye, C | 1 |
| Schraufnagel, DE | 1 |
| Bruner, LH; Bull, RW; Roth, RA | 1 |
24 other study(ies) available for monocrotaline and Hypertrophy
| Article | Year |
|---|---|
Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling.
Topics: Animals; Body Weight; Cardiotonic Agents; Collagen Type IV; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Kidney; Lung; Male; Monocrotaline; Organ Size; Peptide Fragments; Rats; Rats, Wistar; Recombinant Proteins; Ventricular Remodeling | 2020 |
Transthoracic Pulmonary Artery Denervation for Pulmonary Arterial Hypertension.
Topics: Adolescent; Aldosterone; Animals; Child, Preschool; Cytokines; Disease Progression; Female; Fibrosis; Gene Expression Regulation; Humans; Hypertrophy; Lung; Male; Middle Aged; Monocrotaline; Neurotransmitter Agents; Oxidative Stress; Pulmonary Arterial Hypertension; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Renin-Angiotensin System; Sympathectomy; Sympathetic Nervous System | 2019 |
Association between endothelial function and micro-vascular remodeling measured by synchrotron radiation pulmonary micro-angiography in pulmonary arterial hypertension.
Topics: Angiography; Animals; Arterial Pressure; Arterioles; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Synchrotrons; Thrombosis; Vascular Endothelial Growth Factor A; Vascular Remodeling | 2016 |
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Guanylate Cyclase; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Immunohistochemistry; Mice; Monocrotaline; Pulmonary Artery; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2008 |
Molecular and electrical remodeling of L- and T-type Ca(2+) channels in rat right atrium with monocrotaline-induced pulmonary hypertension.
Topics: Animals; Calcium Channels, L-Type; Calcium Channels, T-Type; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Atria; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Monocrotaline; Patch-Clamp Techniques; Rats; Rats, Wistar; RNA, Messenger | 2009 |
The effects and mechanisms of mycophenolate mofetil on pulmonary arterial hypertension in rats.
Topics: Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypertrophy; Immunosuppressive Agents; Male; Monocrotaline; Muscle, Smooth, Vascular; Mycophenolic Acid; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2010 |
Reduced mechanical efficiency of rat papillary muscle related to degree of hypertrophy of cardiomyocytes.
Topics: Animals; Biomechanical Phenomena; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy; Male; Monocrotaline; Muscle Relaxation; Myocardial Contraction; Myocytes, Cardiac; Oxygen; Papillary Muscles; Rats; Rats, Wistar | 2010 |
C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats.
Topics: Animals; Arterioles; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood Proteins; Familial Primary Pulmonary Hypertension; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Male; Monocrotaline; Phenothiazines; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.
Topics: Acetylcholine; Acidosis, Respiratory; Airway Remodeling; Ammonium Chloride; Animals; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Cholinergic Agonists; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; In Vitro Techniques; Lung; Male; Monocrotaline; Nitroprusside; Organ Size; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2012 |
Fluoxetine protects against monocrotaline-induced pulmonary arterial remodeling by inhibition of hypoxia-inducible factor-1α and vascular endothelial growth factor.
Topics: Animals; Antihypertensive Agents; Cell Proliferation; Disease Models, Animal; Fluoxetine; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Hypoxia-Inducible Factor 1, alpha Subunit; Lung; Male; MAP Kinase Signaling System; Monocrotaline; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Endothelial Growth Factor A | 2012 |
Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Therapy, Combination; Gelatinases; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Iloprost; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Muscle, Smooth, Vascular; Naphthyridines; Oxygen; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Gas Exchange; Pulmonary Heart Disease; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Ventricular Remodeling | 2004 |
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cell Line; Cytochrome P-450 Enzyme System; Dependovirus; Epoprostenol; Feasibility Studies; Gene Transfer Techniques; Genetic Vectors; Heart Rate; Humans; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Injections, Intramuscular; Intramolecular Oxidoreductases; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Wistar; Survival Analysis | 2007 |
Polyamines and the development of monocrotaline-induced pulmonary hypertension.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood Pressure; Eflornithine; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Kinetics; Lung; Male; Monocrotaline; Ornithine; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines; Putrescine; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio; Spermidine; Spermine | 1984 |
Monocrotaline also causes medial hypertrophy of pulmonary veins.
Topics: Animals; Hypertrophy; Monocrotaline; Plants, Toxic; Pulmonary Veins; Pyrrolizidine Alkaloids; Rats; Senecio | 1981 |
Lactate dehydrogenase activity and isozyme patterns in tissues and bronchoalveolar lavage fluid from rats treated with monocrotaline pyrrole.
Topics: Animals; Bronchoalveolar Lavage Fluid; Electrophoresis; Endothelium, Vascular; Erythrocytes; Heart Ventricles; Hypertrophy; Isoenzymes; L-Lactate Dehydrogenase; Lung; Macrophages; Male; Monocrotaline; Neutrophils; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1994 |
The effect of nifedipine on monocrotaline-induced pulmonary hypertension in rats.
Topics: Acute Disease; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Injections, Intraperitoneal; Monocrotaline; Nifedipine; Organ Size; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley | 1993 |
Bioactivation of monocrotaline by P-450 3A in rat liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Heart; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Immunoglobulin G; Liver; Male; Microsomes, Liver; Monocrotaline; Orchiectomy; Organ Size; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Sex Factors; Ventricular Pressure | 1997 |
Angiotensin-converting enzyme inhibition delays pulmonary vascular neointimal formation.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Cell Division; Disease Models, Animal; Elastic Tissue; Feasibility Studies; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; In Situ Hybridization; Male; Monocrotaline; Organ Size; Pneumonectomy; Poisons; Procollagen; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Tropoelastin; Tunica Intima; Tunica Media | 1998 |
Endothelin converting enzyme inhibitor protects development of right ventricular overload and medial thickening of pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
Topics: Animals; Aspartic Acid Endopeptidases; Blood Pressure; Endothelin-Converting Enzymes; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Male; Metalloendopeptidases; Monocrotaline; Organ Size; Poisons; Pulmonary Artery; Rats; Rats, Wistar; Tetracyclines | 1998 |
Attenuation of pulmonary vascular hypertension and cardiac hypertrophy with sitaxsentan sodium, an orally active ET(A) receptor antagonist.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Isoxazoles; Male; Monocrotaline; Oxygen; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Thiophenes; Vasoconstriction; Weight Gain | 2000 |
Chamber-specific alterations of noradrenaline uptake (uptake(1)) in right ventricles of monocrotaline-treated rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Heart Failure; Heart Ventricles; Hypertrophy; In Vitro Techniques; Male; Membranes; Monocrotaline; Norepinephrine; Piperazines; Rats; Rats, Wistar; Tritium | 2000 |
Increased pulmonary artery elastolytic activity in adult rats with monocrotaline-induced progressive hypertensive pulmonary vascular disease compared with infant rats with nonprogressive disease.
Topics: Age Factors; Animals; Collagen; Elastin; Hypertension, Pulmonary; Hypertrophy; Male; Monocrotaline; Pancreatic Elastase; Pulmonary Artery; Rats; Rats, Inbred Strains | 1992 |
Monocrotaline-induced angiogenesis. Differences in the bronchial and pulmonary vasculature.
Topics: Animals; Capillaries; Female; Hypertrophy; Lung; Microcirculation; Microscopy, Electron, Scanning; Monocrotaline; Neovascularization, Pathologic; Plants, Toxic; Pulmonary Artery; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio | 1990 |
The effect of immunosuppressants and adoptive transfer in monocrotaline pyrrole pneumotoxicity.
Topics: Animals; Antilymphocyte Serum; Body Weight; Bronchoalveolar Lavage Fluid; Cyclosporins; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy; Immunization, Passive; Immunosuppressive Agents; L-Lactate Dehydrogenase; Lung; Lymphocytes; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1987 |